InternationalJournalofAgricultural

Size: px
Start display at page:

Download "InternationalJournalofAgricultural"

Transcription

1 IJASVM InternationalJournalofAgricultural SciencesandVeterinaryMedicine ISSN: Vol.5,No.1,February2017

2 Int. J. Agric.Sc & Vet.Med Arthi A and Tresamol P V, 2017 Research Paper ISSN Vol. 5, No. 1, February All Rights Reserved MOLECULAR IDENTIFICATION OF BABESIA CANIS VOGELI AND ITS THERAPEUTIC MANAGEMENT WITH IMIDOCARB Arthi A 1* and Tresamol P V 2 *Corresponding Author: Arthi A, arthivet@gmail.com A one and a half year old female Labrador was presented with a history of anorexia and vomiting. Hematological abnormalities were thrombocytopenia and monocytosis. Babesia canis piroplasms were detected on blood smear examination and the dog was treated with injection imidocarb at a dose of 6 mg/ kg body weight subcutaneously (SC) twice, with a two week interval. Hematology was performed on day s three and fourteen to assess the improvement. The present communication deals with the identification of the species/subspecies B. canis vogeli by Polymerase Chain Reaction (PCR) and the therapeutic management of the same. Keywords: B. canis vogeli, Imidocarb, Polymerase chain reaction, Thrombocytopenia INTRODUCTION Babesiosis is a tick borne hemoprotozoal disease and two species of babesia affect dogs. Babesia canis the large piroplasm is mainly transmitted by the brown dog tick Rhipicephalus sanguineous and has three subspecies. The three subspecies (currently claimed to be distinct species) of B. canis: B. rossi, B. canis and B. vogeli are morphologically identical but vary in geographic distribution, vector specificity, genetic characteristics and the clinical signs which they induce in dogs (Matjila et al., 2004). Transmission is also possible through iatrogenic means (contaminated needles and surgical instruments) and in utero from dam to puppies (Ayoob et al., 2006). Following is the molecular detection of babesiae subspecies and therapeutic management of canine babesiosis with injection imidocarb. MATERIALS AND METHODS A one and a half year old female Labrador was presented to the University Veterinary Hospital, Kokkalai, Thrissur with a history of anorexia and vomiting since few days. Clinical examination revealed lymphadenopathy, pyrexia (102.8 o F) and 1 M.V.Sc Scholar, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, Thrissur , Kerala Veterinary and Animal Sciences University, Kerala, India. 2 Professor and Head, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, Thrissur , Kerala Veterinary and Animal Sciences University, Kerala, India. 87

3 Int. J. Agric.Sc & Vet.Med Arthi A and Tresamol P V, 2017 palor of mucous membranes. Other vital parameters like pulse, heart rate and respiration rate were within the normal ranges. On abdominal palpation there was splenomegaly. Figure 3: Ethidium Bromide Stained Agarose Gel Electrophoresis of PCR Products from B canis vogeli (Lane 2) Peripheral blood smear examination revealed the presence of B.canis piroplasms within the red blood cells (Figure 1). Anemia, severe thrombocytopenia and monocytosis were evident on hematology. Ultrasonography of the abdomen revealed moderate splenomegaly (Figure 2) and Figure 1: B. canis piroplasms Within the Red Blood Cells Figure 2: Ultrasonography Showing Moderate Splenomegaly the liver and kidneys retained their normal size and architecture. DNA was extracted from 100 µl EDTA-anticoagulated whole blood using the commercial QIAGEN blood and tissue DNA extraction kit as prescribed by the manufacturer. Using the specific forward primer BAB1 (5 0 -GTG AAC CTT ATC ACT TAA AGG-3 0 ) and reverse primer BAB4 (5 0 -CAA CTC CTC CAC GCA ATC G-3 0 ) PCR was performed to amplify an approximately 590 bp B.c. vogeli fragment of the 18S rrna gene of babesiae (Duarte et al., 2008). Amplification conditions were: 2 min at 94 C, 35 cycles each of 94 C for 30 s, 56 C for 30 s, and 72 C for 1 min, with the addition of a final extension period of 6 min at 72 C. The PCR amplicons were visualized by electrophoresis in 88

4 Int. J. Agric.Sc & Vet.Med Arthi A and Tresamol P V, % agarose gel stained with ethidium bromide under UV transillumination (Figure 3). Results were captured and recorded using a digital documentation system. RESULTS AND DISCUSSION The dog was treated with Inj. Imicarb (Imidocarb) at a dose rate of 6 mg/kg SC two doses with a two week interval. Blood for hematology was collected periodically and remarkable improvement was noticed in the platelet counts. A slight reduction in the erythrocyte count and hemoglobin values was noticed. Blood smear examination was repeated after two weeks and four weeks to check for parasitemia. No piroplasms could be detected after treatment. The dog did not show any adverse effects towards the drug. The dog s appetite gradually improved and after third day of treatment remarkable improvement was noticed in the condition. The subspecies was confirmed to be B. canis vogeli which usually causes a mild or moderate clinical disease with hemolytic regenerative anemia (Solano-Gallego et al., 2011). Thrombocytopenia and monocytosis were observed in the current case which correlates with the reports of Salem et al. (2014) as they were the most commonly observed hematological abnormalities. Moderate to marked thrombocytopenia is a common finding as in this case which is mostly immune-mediated or due to splenic sequestration of platelets. The sequestration and destruction of infected and non-infected erythrocytes takes place in the spleen resulting in splenomegaly. Hence the spleen acts as the defense system against babesia infection. Elevations in the platelet count post treatment in our case suggest that the therapeutic response to imidocarb is faster when compared to other anti-babesial drugs. This is also supported by the findings of Mathe and coworkers (Mathe et al., 2006) where the urine colour of hemoglobinuric dogs changes to normal, forty eight hours after imidocarb administration. CONCLUSION The hemolytic syndrome which is an important feature of babesiosis is due to intravascular and extravascular hemolysis caused by parasite destruction and also by auto antibodies directed towards both infected and non-infected red cells. Imidocarb at the above mentioned dose offers prophylaxis for a period of two weeks against B. canis infection. Even though the side effects of imidocarb like hypersalivation, tachycardia, dyspnea, vomiting and diarrhea were reported (Abdullah et al., 1984), no such findings were encountered in the present case. Side effects of imidocarb can be controlled by giving atropine at a dose of mg/kg SC prior to imidocarb administration. REFERENCES 1. Abdullah A S, Sheikh-Omar A R, Baggot J D and Zamri M (1984), Adverse Effects of Imidocarb dipropionate (Imizol ) in a Dog, Vet Res Comm., Vol. 8, pp Ayoob A L, Hackner S G and Prittie J (2010), Clinical Management of Canine Babesiosis, J. Vet. Emergency and Critical Care, Vol. 20, pp Duarte S C, Linhares G F C, Romanowsky T N, da SilveiraNeto O J and Borges L M F (2008), Assessment of Primers Designed for the Subspecies-Specific Discrimination among Babesia canis canis, Babesia canis vogeli and Babesia canis rossi 89

5 Int. J. Agric.Sc & Vet.Med Arthi A and Tresamol P V, 2017 by PCR Assay, Vet. Parasitol, Vol. 152, pp Matjila P T, Penzhorn B L, Bekker C P J, Nijhof A M and Jongejan F (2004), Confirmation of Occurrence of Babesia canis vogeli in Domestic Dogs in South Africa, Vet. Parasitol., Vol. 122, pp Mathe A, Voros K, Papp L and Reiczigel J (2006), Clinical Manifestations of Canine Babesiosis in Hungary (63 Cases), Acta Veterinaria Hungarica, Vol. 54, pp Salem N Y and Farag H S (2014), Clinical, Hematologic, and Molecular Findings in Naturally Occurring Babesia canis vogeli in Egyptian Dogs, Vet. Med. Intern. 7. Solano-Gallego L and Baneth G (2011), Babesiosis in Dogs and Cats Expanding Parasitological and Clinical Spectra, Vet. Parasitol., Vol. 181, pp APPENDIX Table 1: Hematology on Day 0, 3 and 14 Parameter Day 0 Day 3 Day 14 Ref. Range Hb (g/dl) RBC/mm W BC/mm VPRC (%) M CV (fl) M CH (pg) MCHC (%) Platelet count (lacs/mm 3 ) Lymphocytes M onocytes Granulocytes

6

Case Report Peritoneal Effusion in a Dog due to Babesia gibsoni Infection

Case Report Peritoneal Effusion in a Dog due to Babesia gibsoni Infection Case Reports in Veterinary Medicine, Article ID 807141, 4 pages http://dx.doi.org/10.1155/2014/807141 Case Report Peritoneal Effusion in a Dog due to Babesia gibsoni Infection Suresh Gonde, 1 Sushma Chhabra,

More information

An Overview of Canine Babesiosis

An Overview of Canine Babesiosis Page 1 of 6 C. Wyatt Cleveland, DVM; David S. Peterson, DVM, PhD; and Kenneth S. Latimer, DVM, PhD Class of 2002 (Cleveland), Department of Medical Microbiology and Parasitology (Peterson), and Department

More information

PCR detection of Leptospira in. stray cat and

PCR detection of Leptospira in. stray cat and PCR detection of Leptospira in 1 Department of Pathology, School of Veterinary Medicine, Islamic Azad University, Shahrekord Branch, Shahrekord, Iran 2 Department of Microbiology, School of Veterinary

More information

Pathogenesis of E. canis

Pathogenesis of E. canis Tick-born disease Rhipicephalus sanguineus brown dog tick Rickettsia Ehrlichia canis Ehrlichia platys Anaplasma platys Pathogenesis of E. canis Incubation period: 8 20 days Mononuclear cells Liver, spleen,

More information

INFLUENCE OF ANAEMIA ON AZOTAEMIA IN DOGS INFECTED WITH BABESIA CANIS IN POLAND

INFLUENCE OF ANAEMIA ON AZOTAEMIA IN DOGS INFECTED WITH BABESIA CANIS IN POLAND Bull Vet Inst Pulawy 53, 663-668, 2009 INFLUENCE OF ANAEMIA ON AZOTAEMIA IN DOGS INFECTED WITH BABESIA CANIS IN POLAND WOJCIECH ZYGNER AND HALINA WĘDRYCHOWICZ 1, 2 1 Division of Parasitology and Parasitic

More information

The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA

The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA Veterinary Parasitology 146 (2007) 316 320 www.elsevier.com/locate/vetpar The detection of Cytauxzoon felis in apparently healthy free-roaming cats in the USA Marion D. Haber a, Melissa D. Tucker a, Henry

More information

Clinicopathological findings in dogs naturally infected dogs with Babesia

Clinicopathological findings in dogs naturally infected dogs with Babesia Albanian j. agric. sci. 2013;12 (2): 185-189 Agricultural University of Tirana RESEARCH ARTICLE Correspondence: egon Andoni, Affiliation; Agricultural University of Tirana Email: egon-andoni@yahoo.com

More information

Ehrlichiosis, Anaplasmosis and other Vector Borne Diseases You May Not Be Thinking About Richard E Goldstein Cornell University Ithaca NY

Ehrlichiosis, Anaplasmosis and other Vector Borne Diseases You May Not Be Thinking About Richard E Goldstein Cornell University Ithaca NY Ehrlichiosis, Anaplasmosis and other Vector Borne Diseases You May Not Be Thinking About Richard E Goldstein Cornell University Ithaca NY Canine Monocytic Ehrlichiosis Ehrlichia canis The common etiologic

More information

Canine babesiosis is an emerging hemoprotozoan

Canine babesiosis is an emerging hemoprotozoan J Vet Intern Med 2010;24:127 131 Babesiosis Caused by a Large Babesia Species in 7 Immunocompromised Dogs L.E. Sikorski, A.J. Birkenheuer, M.K. Holowaychuk, A.L. McCleary-Wheeler, J.M. Davis, and M.P.

More information

DIAGNOSIS AND MANAGEMENT OF CHOLECYSTITIS IN DOGS

DIAGNOSIS AND MANAGEMENT OF CHOLECYSTITIS IN DOGS Int. J. Agric.Sc & Vet.Med. 2014 K Satish Kumar and D Srikala, 2014 Research Paper ISSN 2320-3730 www.ijasvm.com Vol. 2, No. 3, August 2014 2014 www.ijasvm.com. All Rights Reserved DIAGNOSIS AND MANAGEMENT

More information

Ehrlichia and Anaplasma: What Do We Need to Know in NY State Richard E Goldstein DVM DACVIM DECVIM-CA The Animal Medical Center New York, NY

Ehrlichia and Anaplasma: What Do We Need to Know in NY State Richard E Goldstein DVM DACVIM DECVIM-CA The Animal Medical Center New York, NY Ehrlichia and Anaplasma: What Do We Need to Know in NY State Richard E Goldstein DVM DACVIM DECVIM-CA The Animal Medical Center New York, NY Learning Objectives The attendees will be familiar with the

More information

Canine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys

Canine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys Canine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys It takes just hours for an infected tick to transmit Anaplasma organisms to a dog. What is canine anaplasmosis? Canine anaplasmosis is a disease

More information

Veterinary Parasitology

Veterinary Parasitology Veterinary Parasitology 186 (2012) 159 164 Contents lists available at SciVerse ScienceDirect Veterinary Parasitology jo u rn al hom epa ge : www.elsevier.com/locate/vetpar The therapeutic efficacy of

More information

Tick-borne Disease Testing in Shelters What Does that Blue Dot Really Mean?

Tick-borne Disease Testing in Shelters What Does that Blue Dot Really Mean? Tick-borne Disease Testing in Shelters What Does that Blue Dot Really Mean? 2017 ASPCA. All Rights Reserved. Your Presenter Stephanie Janeczko, DVM, MS, DABVP, CAWA Senior Director of Shelter Medical Programs

More information

MURDOCH RESEARCH REPOSITORY

MURDOCH RESEARCH REPOSITORY MURDOCH RESEARCH REPOSITORY http://researchrepository.murdoch.edu.au/20636/ Irwin, P.J. (2007) Blood, bull terriers and babesiosis: a review of canine babesiosis. In: 32nd Annual World Small Animal Veterinary

More information

International Journal of Science, Environment and Technology, Vol. 6, No 6, 2017,

International Journal of Science, Environment and Technology, Vol. 6, No 6, 2017, International Journal of Science, Environment and Technology, Vol. 6, No 6, 2017, 3362 3366 ISSN 2278-3687 (O) 2277-663X (P) CONCURRENT HAEMOPROTOZOAN AND ENDOPARASITIC INFECTION IN GOATS *Subramanian

More information

1. Babesia bigemina. 2. Anaplasma marginale. 3. Theileria orientalis. 4. Trypanosoma evansi. Vector: Rhipicephalus (Boophilus) microplus.

1. Babesia bigemina. 2. Anaplasma marginale. 3. Theileria orientalis. 4. Trypanosoma evansi. Vector: Rhipicephalus (Boophilus) microplus. 1. Babesia bigemina. Vector: Rhipicephalus (Boophilus) microplus. 2. Anaplasma marginale. Vector: Rhipicephalus (Boophilus) microplus. 3. Theileria orientalis. Vector: Rhipicephalus (Boophilus) microplus.

More information

COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS

COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS The European Agency for the Evaluation of Medicinal Products Veterinary Medicines and Information Technology EMEA/CVMP/005/00-FINAL-Rev.1 COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS GUIDELINE FOR THE TESTING

More information

How to talk to clients about heartworm disease

How to talk to clients about heartworm disease Client Communication How to talk to clients about heartworm disease Detecting heartworm infection early generally allows for a faster and more effective response to treatment. Answers to pet owners most

More information

Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles

Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles. Blood Cells of Reptiles INTRODUCTION TO REPTILE HEMATOLOGY & CYTOLOGY DVM. PhD Dec 14 2014 Leukocytes Thrombocytes Similar diagnostic principles as Mammals. Similar in function as Avian. Much more unknowns and variables in Reptiles.

More information

Use of Artemisinin to Treat Mycoplasma haemolamae Infection in Llamas

Use of Artemisinin to Treat Mycoplasma haemolamae Infection in Llamas Use of Artemisinin to Treat Mycoplasma haemolamae Infection in Llamas Jessica Puccetti BioResource Research, Susan Tornquist DVM, PhD. Biomedical Sciences, College of Veterinary Medicine Objective The

More information

Heartworm Disease in Dogs

Heartworm Disease in Dogs Customer Name, Street Address, City, State, Zip code Phone number, Alt. phone number, Fax number, e-mail address, web site Heartworm Disease in Dogs Basics OVERVIEW Disease caused by infestation with heartworms

More information

Comparison of Resistance to Theileria sergenti Infection between Holstein and Japanese Black Cattle under Grazing Conditions

Comparison of Resistance to Theileria sergenti Infection between Holstein and Japanese Black Cattle under Grazing Conditions JARQ 31, 19-3 (1997) Comparison of Resistance to Theileria sergenti Infection between Holstein and Japanese Black Cattle under Grazing Conditions Yutaka TERADA* 1, Yoshihiro KARIYA*, Shinichi TERUI* 3,

More information

SUMMARY Of the PhD thesis entitled RESEARCH ON THE EPIDEMIOLOGY, DIAGNOSIS AND CONTROL OF CANINE BABESIOSIS IN WESTERN ROMANIA

SUMMARY Of the PhD thesis entitled RESEARCH ON THE EPIDEMIOLOGY, DIAGNOSIS AND CONTROL OF CANINE BABESIOSIS IN WESTERN ROMANIA This thesis contains: Summaries (Romanian, English, French) Extended general part 55 pages; Extended own research part 137 pages; Tables: 11; Figures full color: 111; References: 303 references. SUMMARY

More information

Blood protozoan: Plasmodium

Blood protozoan: Plasmodium Blood protozoan: Plasmodium Dr. Hala Al Daghistani The causative agent of including Plasmodium vivax P. falciparum P. malariae P. ovale. malaria in humans: four species are associated The Plasmodium spp.

More information

Double-Blind, Placebo-Controlled, Randomized Study of Dipyrone as a Treatment for Pyrexia in Horses

Double-Blind, Placebo-Controlled, Randomized Study of Dipyrone as a Treatment for Pyrexia in Horses Double-Blind, Placebo-Controlled, Randomized Study of Dipyrone as a Treatment for Pyrexia in Horses Emily Sundman, DVM Ming Yin, PhD Tianhua Hu, PhD Melinda Poole, DVM Disclosures Sundman, Yin, Hu, and

More information

A2-year-old neutered. Diagnosing FHM in anemic patients

A2-year-old neutered. Diagnosing FHM in anemic patients Diagnosing FHM in anemic patients Feline hemotrophic mycoplasmosis can be a difficult disease to pinpoint, but there are ways to make a successful diagnosis. By Jennifer Jellison, DVM Contributing Author

More information

Suggested vector-borne disease screening guidelines

Suggested vector-borne disease screening guidelines Suggested vector-borne disease screening guidelines SNAP Dx Test Screen your dog every year with the SNAP Dx Test to detect exposure to pathogens that cause heartworm disease, ehrlichiosis, Lyme disease

More information

Blood protozoan: Plasmodium

Blood protozoan: Plasmodium Blood protozoan: Plasmodium The causative agent of including Plasmodium vivax P. falciparum P. malariae P. ovale. malaria in humans:four species are associated The Plasmodium spp. life cycle can be divided

More information

The Epidemiological Survey and Analysis of Canine Babesiosis in Xi an City, China

The Epidemiological Survey and Analysis of Canine Babesiosis in Xi an City, China Animal and Veterinary Sciences 2018; 6(3): 43-50 http://www.sciencepublishinggroup.com/j/avs doi: 10.11648/j.avs.20180603.12 ISSN: 2328-5842 (Print); ISSN: 2328-5850 (Online) Report The Epidemiological

More information

A Theileria sp. was detected by PCR in blood samples collected from dogs in the

A Theileria sp. was detected by PCR in blood samples collected from dogs in the Chapter 6: Detection of Theileria sp. infections in dogs in South Africa. 6.1. Abstract A Theileria sp. was detected by PCR in blood samples collected from dogs in the Pietermaritzburg area and also found

More information

Review on status of babesiosis in humans and animals in Iran

Review on status of babesiosis in humans and animals in Iran Review on status of babesiosis in humans and animals in Iran Mousa Tavassoli, Sepideh Rajabi Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Babesiosis is a zoonotic

More information

Adopting a dog from Spain comes with some risks of which you should be aware.

Adopting a dog from Spain comes with some risks of which you should be aware. LHB Galgo Rescue Information for your Vet Adopting a dog from Spain comes with some risks of which you should be aware. Nearly all Spanish shelters test for Babesia, Ehrlichia, Leishmania and heartworm

More information

Title. Author(s)Shiranaga, Nobuyuki; Inokuma, Hisashi. CitationJapanese Journal of Veterinary Research, 66(3): 221- Issue Date DOI.

Title. Author(s)Shiranaga, Nobuyuki; Inokuma, Hisashi. CitationJapanese Journal of Veterinary Research, 66(3): 221- Issue Date DOI. Title Effects of low-dose diminazene aceturate injection followed by clindamycin administration for treating Author(s)Shiranaga, Nobuyuki; Inokuma, Hisashi CitationJapanese Journal of Veterinary Research,

More information

both are fatal diseases. In babesiosis blood comes out with the urine and hence it is also known as Red water disease. Theileria vaccines are not

both are fatal diseases. In babesiosis blood comes out with the urine and hence it is also known as Red water disease. Theileria vaccines are not 1.1 INTRODUCTION Animal husbandry plays an important role in Indian agriculture. Indians by large are vegetarian and as such the only source of animal protein is milk and milk products. With the increasing

More information

INCIDENCE OF CANINE DISTEMPER INFECTION IN AND AROUND MHOW REGION OF MADHYA PRADESH

INCIDENCE OF CANINE DISTEMPER INFECTION IN AND AROUND MHOW REGION OF MADHYA PRADESH Int. J. Agric.Sc & Vet.Med. 2013 Jyoti Dongre et al., 2013 Research Paper ISSN 2320-3730 www.ijasvm.com Vol. 1, No. 4, November 2013 2013 www.ijasvm.com. All Rights Reserved INCIDENCE OF CANINE DISTEMPER

More information

Topics. Ticks on dogs in North America. Ticks and tick-borne diseases: emerging problems? Andrew S. Peregrine

Topics. Ticks on dogs in North America. Ticks and tick-borne diseases: emerging problems? Andrew S. Peregrine Ticks and tick-borne diseases: emerging problems? Andrew S. Peregrine E-mail: aperegri@ovc.uoguelph.ca Topics Ticks on dogs in Ontario and the pathogens they transmit? Should dogs be routinely screened

More information

Veterinary Parasitology

Veterinary Parasitology Veterinary Parasitology 172 (2010) 311 316 Contents lists available at ScienceDirect Veterinary Parasitology journal homepage: www.elsevier.com/locate/vetpar Identification and genetic characterization

More information

Tick-Borne Disease Diagnosis: Moving from 3Dx to 4Dx AND it s MUCH more than Blue Dots! indications implications

Tick-Borne Disease Diagnosis: Moving from 3Dx to 4Dx AND it s MUCH more than Blue Dots! indications implications Tick-Borne Disease Diagnosis: Moving from 3Dx to 4Dx Richard B. Ford, DVM, MS Professor of Medicine Diplomate ACVIM and (Hon) ACVPM North Carolina State University Raleigh, NC In just the past 3 to 5 years,

More information

Blood Cell Characteristics and Some Hematological Values of American Pit-bull Terriers in Thailand

Blood Cell Characteristics and Some Hematological Values of American Pit-bull Terriers in Thailand World Applied Sciences Journal 2 (3): 158-162, 2007 ISSN 1818-4952 IDOSI Publications, 2007 Blood Cell Characteristics and Some Hematological Values of American Pit-bull Terriers in Thailand W. Aengwanich,

More information

Tackle Ticks: Babesiosis

Tackle Ticks: Babesiosis Vet Times The website for the veterinary profession https://www.vettimes.co.uk Tackle Ticks: Babesiosis Author : Simon Tappin Categories : Canine, Companion animal, Feline, General, Practical, RVNs, Species,

More information

however, the mild weather and moisture we have had these past couple of weeks have been

however, the mild weather and moisture we have had these past couple of weeks have been Be on the lookout for anaplasmosis in cattle Carla L. Huston, DVM, PhD, ACVPM Dept. of Pathobiology and Population Medicine Mississippi State University College of Veterinary Medicine Submitted to Cattle

More information

PLASMODIUM MODULE 39.1 INTRODUCTION OBJECTIVES 39.2 MALARIAL PARASITE. Notes

PLASMODIUM MODULE 39.1 INTRODUCTION OBJECTIVES 39.2 MALARIAL PARASITE. Notes Plasmodium MODULE 39 PLASMODIUM 39.1 INTRODUCTION Malaria is characterized by intermittent fever associated with chills and rigors in the patient. There may be enlargement of the liver and spleen in the

More information

Ticks and tick-borne diseases

Ticks and tick-borne diseases Occupational Diseases Ticks and tick-borne diseases Ticks Ticks are small, blood sucking arthropods related to spiders, mites and scorpions. Ticks are only about one to two millimetres long before they

More information

RICKETTSIA SPECIES AMONG TICKS IN AN AREA OF JAPAN ENDEMIC FOR JAPANESE SPOTTED FEVER

RICKETTSIA SPECIES AMONG TICKS IN AN AREA OF JAPAN ENDEMIC FOR JAPANESE SPOTTED FEVER RICKETTSIA SPECIES AMONG TICKS IN AN AREA OF JAPAN ENDEMIC FOR JAPANESE SPOTTED FEVER Makoto Kondo 1, Katsuhiko Ando 2, Keiichi Yamanaka 1 and Hitoshi Mizutani 1 1 Department of Dermatology, 2 Department

More information

Screening for vector-borne disease. SNAP 4Dx Plus Test clinical reference guide

Screening for vector-borne disease. SNAP 4Dx Plus Test clinical reference guide Screening for vector-borne disease SNAP 4Dx Plus Test clinical reference guide Every dog, every year The Companion Animal Parasite Council (CAPC) Guidelines recommend annual comprehensive screening for

More information

What s Your Diagnosis?

What s Your Diagnosis? What s Your Diagnosis? Signalment: Maine Coone (8 month old, female intact) Presenting complaint: Lethargy, inappetence, serosanguinous vaginal discharge History: Lives with 11 other Maine Coone cats (males

More information

International Journal of Science, Environment and Technology, Vol. 7, No 3, 2018,

International Journal of Science, Environment and Technology, Vol. 7, No 3, 2018, International Journal of Science, Environment and Technology, Vol. 7, No 3, 2018, 872 876 ISSN 2278-3687 (O) 2277-663X (P) SURGICAL MANAGEMENT OF INTESTINAL OBSTRUCTION DUE TO BRISTLES OF SWEEP BROOM IN

More information

EHRLICHIOSIS IN DOGS IMPORTANCE OF TESTING FOR CONTRIBUTING AUTHORS CASE 1: SWIGGLES INTRODUCTION WITH PERSISTENT LYMPHOCYTOSIS

EHRLICHIOSIS IN DOGS IMPORTANCE OF TESTING FOR CONTRIBUTING AUTHORS CASE 1: SWIGGLES INTRODUCTION WITH PERSISTENT LYMPHOCYTOSIS THE IMPORTANCE OF TESTING FOR EHRLICHIOSIS IN DOGS WITH PERSISTENT LYMPHOCYTOSIS Contributing Authors: Mary Anna Thrall, DVM, MS, DACVP Diana Scorpio, DVM, MS, DACLAM Ross University School of Veterinary

More information

Biology 120 Lab Exam 2 Review

Biology 120 Lab Exam 2 Review Biology 120 Lab Exam 2 Review Student Learning Services and Biology 120 Peer Mentors Sunday, November 26 th, 2017 4:00 pm Arts 263 Important note: This review was written by your Biology Peer Mentors (not

More information

Screening for vector-borne disease. SNAP 4Dx Plus Test clinical reference guide

Screening for vector-borne disease. SNAP 4Dx Plus Test clinical reference guide Screening for vector-borne disease SNAP 4Dx Plus Test clinical reference guide Every dog, every year The Companion Animal Parasite Council (CAPC) Guidelines recommend annual comprehensive screening for

More information

PREVALENCE OF RENAL DISORDERS IN DOGS A CLINICAL STUDY

PREVALENCE OF RENAL DISORDERS IN DOGS A CLINICAL STUDY Int. J. Agric.Sc & Vet.Med. 2014 Satish Kumar Karlapudi and Srikanth Kandula, 2014 Research Paper ISSN 2320-3730 www.ijasvm.com Vol. 2, No. 3, August 2014 2014 www.ijasvm.com. All Rights Reserved PREVALENCE

More information

Acute Hemorrhagic Diarrhea Syndrome (AHDS) A Cause of Bloody Feces in Dogs

Acute Hemorrhagic Diarrhea Syndrome (AHDS) A Cause of Bloody Feces in Dogs Acute Hemorrhagic Diarrhea Syndrome (AHDS) A Cause of Bloody Feces in Dogs No dog parent wants to clean up diarrhea. Cleaning up bloody diarrhea is even more unpleasant. Unfortunately, the development

More information

Medical Genetics and Diagnosis Lab #3. Gel electrophoresis

Medical Genetics and Diagnosis Lab #3. Gel electrophoresis Medical Genetics and Diagnosis Lab #3 Gel electrophoresis Background Information Gel electrophoresis is the standard lab procedure for separating DNA by size (e.g. length in base pairs) for visualization

More information

CERTIFIED REFERENCE MATERIAL IRMM 313

CERTIFIED REFERENCE MATERIAL IRMM 313 EUROPEAN COMMISSION JOINT RESEARCH CENTRE Institute for Reference Materials and Measurements (Geel) CERTIFIED REFERENCE MATERIAL IRMM 313 CERTIFICATE OF ANALYSIS PFGE AGAROSE PLUGS Certified value 2) SmaI

More information

Correspondence should be addressed to King Shimumbo Nalubamba;

Correspondence should be addressed to King Shimumbo Nalubamba; Journal of Parasitology Research Volume 2015, Article ID 985015, 9 pages http://dx.doi.org/10.1155/2015/985015 Research Article A Study of Naturally Acquired Canine Babesiosis Caused by Single and Mixed

More information

Copper-Storage Liver Disease Basics

Copper-Storage Liver Disease Basics Copper-Storage Liver Disease Basics OVERVIEW Abnormal accumulation of copper in the liver, causing sudden (acute) inflammation of the liver (hepatitis) or long-term (chronic) hepatitis and eventually progressive

More information

Annual Screening for Vector-borne Disease. The SNAP 4Dx Plus Test Clinical Reference Guide

Annual Screening for Vector-borne Disease. The SNAP 4Dx Plus Test Clinical Reference Guide Annual Screening for Vector-borne Disease The SNAP Dx Plus Test Clinical Reference Guide Every dog, every year For healthier pets and so much more. The benefits of vector-borne disease screening go far

More information

Acute Pyelonephritis POAC Guideline

Acute Pyelonephritis POAC Guideline Acute Pyelonephritis POAC Guideline Refer full regional pathway http://aucklandregion.healthpathways.org.nz/33444 EXCLUSION CRITERIA: COMPLICATED PYELONEPHRITIS Discuss with relevant specialist for advice

More information

Multiplex real-time PCR for the passive surveillance of ticks, tick-bites, and tick-borne pathogens

Multiplex real-time PCR for the passive surveillance of ticks, tick-bites, and tick-borne pathogens Multiplex real-time PCR for the passive surveillance of ticks, tick-bites, and tick-borne pathogens Guang Xu, Stephen Rich Laboratory of Medical Zoology University of Massachusetts Amherst TICKS ARE VECTORS

More information

Fact sheet. A u s t r a l i a n w ildlife. Introductory statement. Aetiology. Natural hosts. World distribution. Occurrences in Australia

Fact sheet. A u s t r a l i a n w ildlife. Introductory statement. Aetiology. Natural hosts. World distribution. Occurrences in Australia P iroplasms ( B abesia s p p. a n d T h e ileria s p p. ) in A u s t r a l i a n w ildlife Fact sheet Introductory statement Babesia spp. and Theileria spp. are protozoan haemoparasites which invade the

More information

Diseases of the Travelling Pet Part 4

Diseases of the Travelling Pet Part 4 Diseases of the Travelling Pet Part 4 Emerging Diseases and Chemoprophylaxis Ian Wright BVMS, MSc, MRCVS www.vet-ecpd.com www.centralcpd.co.uk Diseases of the travelling pet Ian Wright BVMS.Bsc. Msc. MRCVS

More information

NA 100 R. Multi-functional electrophoresis device

NA 100 R. Multi-functional electrophoresis device NA 100 R Multi-functional electrophoresis device No need for UV transilluminator and darkroom You can see DNA bands after 2 or 3 minutes of electrophoresis You can check 80 PCR products at a time. No need

More information

New Insights into the Treatment of Leishmaniasis

New Insights into the Treatment of Leishmaniasis New Insights into the Treatment of Leishmaniasis Eric Zini Snow meeting, 14 March 2009 Few drugs available for dogs Initially developed to treat human leishmaniasis, later adopted in dogs None eradicates

More information

MEDICAL MANAGEMENT OF THEILERIOSIS WITH ABOMASAL IMPACTION IN A CALF Prasanth CR 1 and Ajithkumar S 2

MEDICAL MANAGEMENT OF THEILERIOSIS WITH ABOMASAL IMPACTION IN A CALF Prasanth CR 1 and Ajithkumar S 2 International Journal of Science, Environment and Technology, Vol. 5, No 6, 2016, 3838 3842 ISSN 2278-3687 (O) 2277-663X (P) MEDICAL MANAGEMENT OF THEILERIOSIS WITH ABOMASAL IMPACTION IN A CALF Prasanth

More information

Detection of Babesia canis vogeli, Babesia gibsoni and Ehrlichia canis by multiplex PCR in naturally infected dogs in South India

Detection of Babesia canis vogeli, Babesia gibsoni and Ehrlichia canis by multiplex PCR in naturally infected dogs in South India . Veterinarski Arhiv 88 (2), 215-224, 2018 DOI: 10.24099/vet.arhiv.161229 Detection of Babesia canis vogeli, Babesia gibsoni and Ehrlichia canis by multiplex PCR in naturally infected dogs in South India

More information

Molecular Characterization of Staphylococcus aureus of Camel (Camelus dromedarius) Skin Origin

Molecular Characterization of Staphylococcus aureus of Camel (Camelus dromedarius) Skin Origin International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 01 (2018) Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2018.701.410

More information

Outlines. Introduction Prevalence Resistance Clinical presentation Diagnosis Management Prevention Case presentation Achievements

Outlines. Introduction Prevalence Resistance Clinical presentation Diagnosis Management Prevention Case presentation Achievements Amal Meas Al-Anizi, PharmD Candidate KSU, Infectious Disease Rotation 2014 Outlines Introduction Prevalence Resistance Clinical presentation Diagnosis Management Prevention Case presentation Achievements

More information

The relationship between the degree of thrombocytopenia and infection with Ehrlichia canis in an endemic area

The relationship between the degree of thrombocytopenia and infection with Ehrlichia canis in an endemic area The relationship between the degree of thrombocytopenia and infection with Ehrlichia canis in an endemic area Camilo Bulla, Regina Takahira, João Pessoa Araújo Jr., Luzia Aparecidatrinca, Raimundo Lopes,

More information

What s Your Diagnosis? By Sohaila Jafarian, Class of 2018

What s Your Diagnosis? By Sohaila Jafarian, Class of 2018 Signalment: Greeley, 3 yo MC DSH Presenting Complaint: ADR History: What s Your Diagnosis? By Sohaila Jafarian, Class of 2018 Patient is an indoor/outdoor cat. Previously healthy and up to date on vaccines

More information

Outline 4/25/2009. Cytauxzoonosis: A tick-transmitted parasite of domestic and wild cats in the southeastern U.S. What is Cytauxzoonosis?

Outline 4/25/2009. Cytauxzoonosis: A tick-transmitted parasite of domestic and wild cats in the southeastern U.S. What is Cytauxzoonosis? Cytauxzoonosis: A tick-transmitted parasite of domestic and wild cats in the southeastern U.S. Michelle Rosen Center for Wildlife Health Department of Forestry, Wildlife, & Fisheries What is Cytauxzoonosis?

More information

6/10/2015. Multi Purpose Canine (MPC) Restraint and Physical Examination PFN: Terminal Learning Objective. Hours: Instructor:

6/10/2015. Multi Purpose Canine (MPC) Restraint and Physical Examination PFN: Terminal Learning Objective. Hours: Instructor: Multi Purpose Canine (MPC) Restraint and Physical Examination PFN: Hours: Instructor: Slide 1 Slide 2 Terminal Learning Objective Action: Communicate knowledge of Multi Purpose Canine (MPC) restraint and

More information

Review article CANINE BABESIOSIS: WHERE DO WE STAND? BILIĆ Petra 1, KULEŠ Josipa 2, BARIĆ RAFAJ Renata 3 1, 2* , MRLJAK Vladimir INTRODUCTION

Review article CANINE BABESIOSIS: WHERE DO WE STAND? BILIĆ Petra 1, KULEŠ Josipa 2, BARIĆ RAFAJ Renata 3 1, 2* , MRLJAK Vladimir INTRODUCTION Review article CANINE BABESIOSIS: WHERE DO WE STAND? Acta Veterinaria-Beograd 2018, 68 (2), 127-160 UDK: 636.7.09:616.993.19 DOI: 10.2478/acve-2018-0011 BILIĆ Petra 1, KULEŠ Josipa 2, BARIĆ RAFAJ Renata

More information

Veterinary Parasitology

Veterinary Parasitology Veterinary Parasitology 196 (2013) 44 49 Contents lists available at SciVerse ScienceDirect Veterinary Parasitology jou rn al h om epa ge: www.elsevier.com/locate/vetpar Tick-borne pathogens and disease

More information

SHE SINGS ALONG TO EVERY SONG...

SHE SINGS ALONG TO EVERY SONG... Prevention. Protection. SHE SINGS ALONG TO EVERY SONG... Protect your best friend with the 5-IN-1 HEARTWORM MEDICINE THAT USES LUFENURON TO STOP FLEAS BEFORE THEY START. Prevention. Protection. POWERED

More information

Fatal Babesia canis canis infection in a splenectomized Estonian dog

Fatal Babesia canis canis infection in a splenectomized Estonian dog DOI 10.1186/s13028-016-0189-4 Acta Veterinaria Scandinavica CASE REPORT Open Access Fatal Babesia canis canis infection in a splenectomized Estonian dog Valentina Tiškina 1*, Valentina Capligina 2, Külli

More information

NUMBER: /2005

NUMBER: /2005 Purpose PAGE 1 OF 7 The purpose of this policy is to describe the procedures for keeping and maintaining animal medical records. This procedure is approved by the Creighton University Institutional Animal

More information

CURRICULUM VITAE. Piyanan Taweethavonsawat. University, Bangkok, Thailand M.Sc. (Pathobiology) Faculty of Veterinary Medicine,

CURRICULUM VITAE. Piyanan Taweethavonsawat. University, Bangkok, Thailand M.Sc. (Pathobiology) Faculty of Veterinary Medicine, CURRICULUM VITAE Personal Data Name Piyanan Taweethavonsawat Date of Birth July 11, 1974 Place of Birth Civil status Nationality Bangkok, Thailand Single Thai Academic qualifications 1991-1996 D.V.M. Faculty

More information

A Possible Treatment Strategy and Clinical Factors to Estimate the Treatment Response in Bebesia gibsoni Infection

A Possible Treatment Strategy and Clinical Factors to Estimate the Treatment Response in Bebesia gibsoni Infection NOTE Internal Medicine A Possible Treatment Strategy and Clinical Factors to Estimate the Treatment Response in Bebesia gibsoni Infection Koretoki SUZUKI 1), Haruna WAKABAYASHI 1), Masashi TAKAHASHI 1,3),

More information

a pit-bull terrier pup recently imported into South Africa.

a pit-bull terrier pup recently imported into South Africa. Chapter 7: Molecular characterization of Babesia gibsoni infection from a pit-bull terrier pup recently imported into South Africa. 7.1. Abstract Canine babesiosis caused by Babesia gibsoni was diagnosed

More information

*Corresponding Author:

*Corresponding Author: Original Research Article DOI: 10.18231/2394-5478.2017.0098 Prevalence and factors associated with the nasal colonization of Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus among

More information

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Veterinary Emergency and Critical Care Paper 1

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Veterinary Emergency and Critical Care Paper 1 Australian and New Zealand College of Veterinary Scientists Membership Examination June 2014 Veterinary Emergency and Critical Care Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours

More information

Outbreaks of Anaplasmosis in Dairy Cattle in Punjab, India

Outbreaks of Anaplasmosis in Dairy Cattle in Punjab, India DOI: 10.5958/2277-940X.2017.00135.8 Journal of Animal Research: v.7 n.5, p. 885-889. October 2017 Outbreaks of Anaplasmosis in Dairy Cattle in Punjab, India Mandeep Singh Bal 1*, Vishal Mahajan 1, Gursimarn

More information

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Veterinary Anaesthesia and Critical Care Paper 1

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Veterinary Anaesthesia and Critical Care Paper 1 Australian and New Zealand College of Veterinary Scientists Membership Examination June 2015 Veterinary Anaesthesia and Critical Care Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours

More information

Molecular diagnosis of Theileria infections in wildlife from Southern Africa ~ implications for accurate diagnosis.

Molecular diagnosis of Theileria infections in wildlife from Southern Africa ~ implications for accurate diagnosis. Molecular diagnosis of Theileria infections in wildlife from Southern Africa ~ implications for accurate diagnosis. Ronel Pienaar Parasites Vectors and Vector-borne Diseases Onderstepoort Veterinary Institute

More information

Infection with a Proposed New Subspecies of Babesia canis, Babesia canis subsp. presentii, in Domestic Cats

Infection with a Proposed New Subspecies of Babesia canis, Babesia canis subsp. presentii, in Domestic Cats JOURNAL OF CLINICAL MICROBIOLOGY, Jan. 2004, p. 99 105 Vol. 42, No. 1 0095-1137/04/$08.00 0 DOI: 10.1128/JCM.42.1.99 105.2004 Copyright 2004, American Society for Microbiology. All Rights Reserved. Infection

More information

The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs

The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs The ability of an oral formulation of afoxolaner to block the transmission of Babesia canis by Dermacentor reticulatus ticks to dogs Frederic Beugnet 1* * Corresponding author Email: Frederic.beugnet@merial.com

More information

NUMBER: R&C-ARF-10.0

NUMBER: R&C-ARF-10.0 1. PURPOSE PAGE 1 OF 6 This policy describes the procedures for keeping and maintaining animal medical records. This procedure is approved by the Creighton University Institutional Animal Care and Use

More information

Vaccines for Cats. 2. Feline viral rhinotracheitis, FVR caused by FVR virus, also known as herpes virus type 1, FHV-1

Vaccines for Cats. 2. Feline viral rhinotracheitis, FVR caused by FVR virus, also known as herpes virus type 1, FHV-1 Vaccines for Cats Recent advances in veterinary medical science have resulted in an increase in the number and type of vaccines that are available for use in cats, and improvements are continuously being

More information

MINISTRY OF HEALTH, MALAYSIA

MINISTRY OF HEALTH, MALAYSIA LAMPIRAN C Ref. No : Photo 4 x 6 ( Part I : Personal information ) 1. FULL NAME ( FIRST NAME) : ( FATHER'S NAME) : 2. MALE/FEMALE : 3. AGE : 7. NAME OF EMPLOYER / RECRUITING AGENCY : 8. ADDRESS OF EMPLOYER

More information

Parasitology Division, National Veterinary Research Institute, PMB 01 Vom Plateau State, Nigeria * Association

Parasitology Division, National Veterinary Research Institute, PMB 01 Vom Plateau State, Nigeria * Association !" #$%$ &'()*+# Parasitology Division, National Veterinary Research Institute, PMB 0 Vom Plateau State, Nigeria * shapumani@yahoo.com +23470355775 + Association of parasitic infection of dogs with packed

More information

370 JFMS CLINICAL PRACTICE

370 JFMS CLINICAL PRACTICE Feline haemoplasma species Mycoplasma haemofelis Often associated with haemolytic anaemia during acute infection. Candidatus Mycoplasma haemominutum May result in a fall in red blood cell parameters, but

More information

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Medicine of Cats Paper 1

Australian and New Zealand College of Veterinary Scientists. Membership Examination. Medicine of Cats Paper 1 Australian and New Zealand College of Veterinary Scientists Membership Examination June 2016 Medicine of Cats Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours after perusal Answer

More information

BOX 1. NAME OF THE VETERINARY MEDICINAL PRODUCT. Hymatil 300 mg/ml solution for injection for cattle and sheep Tilmicosin

BOX 1. NAME OF THE VETERINARY MEDICINAL PRODUCT. Hymatil 300 mg/ml solution for injection for cattle and sheep Tilmicosin BOX 1. NAME OF THE VETERINARY MEDICINAL PRODUCT Hymatil 300 mg/ml solution for injection for cattle and sheep Tilmicosin 2. STATEMENT OF ACTIVE AND OTHER SUBSTANCES Each ml contains: Tilmicosin 300 mg;

More information

Molecular characterization of tick-borne pathogens of domestic dogs from communal areas in Botswana

Molecular characterization of tick-borne pathogens of domestic dogs from communal areas in Botswana Molecular characterization of tick-borne pathogens of domestic dogs from communal areas in Botswana by Donald Ray Sibanda Submitted in partial fulfilment of the requirements for the degree Master of Science

More information

Clinical Manifestations and Treatment of Plague Dr. Jacky Chan. Associate Consultant Infectious Disease Centre, PMH

Clinical Manifestations and Treatment of Plague Dr. Jacky Chan. Associate Consultant Infectious Disease Centre, PMH Clinical Manifestations and Treatment of Plague Dr. Jacky Chan Associate Consultant Infectious Disease Centre, PMH Update of plague outbreak situation in Madagascar A large outbreak since 1 Aug 2017 As

More information

B. PACKAGE LEAFLET 1

B. PACKAGE LEAFLET 1 B. PACKAGE LEAFLET 1 PACKAGE LEAFLET FOR: Cadorex 300 mg/ml solution for injection for cattle, sheep and pigs 1. NAME AND ADDRESS OF THE MARKETING AUTHORISATION HOLDER AND OF THE MANUFACTURING AUTHORISATION

More information

Research Note. A novel method for sexing day-old chicks using endoscope system

Research Note. A novel method for sexing day-old chicks using endoscope system Research Note A novel method for sexing day-old chicks using endoscope system Makoto Otsuka,,1 Osamu Miyashita,,1 Mitsuru Shibata,,1 Fujiyuki Sato,,1 and Mitsuru Naito,2,3 NARO Institute of Livestock and

More information

Is Robenacoxib Superior to Meloxicam in Improving Patient Comfort in Dog Diagnosed With a Degenerative Joint Process?

Is Robenacoxib Superior to Meloxicam in Improving Patient Comfort in Dog Diagnosed With a Degenerative Joint Process? Is Robenacoxib Superior to Meloxicam in Improving Patient Comfort in Dog Diagnosed With a Degenerative Joint Process? A Knowledge Summary by Adam Swallow BVSc MRCVS 1* 1 University of Bristol * Corresponding

More information

NSAID Toxicity in Dogs & Cats Beware of Ibuprofen!

NSAID Toxicity in Dogs & Cats Beware of Ibuprofen! NSAID Toxicity in Dogs & Cats Beware of Ibuprofen! One of the most common drug toxicities in companion animal medicine is accidental ingestion of over-the-counter non-steroid anti-inflammatory (NSAID)

More information