RETROSPECTIVE STUDY OF GRAM NEGATIVE BACILLI ISOLATES AMONG DIFFERENT CLINICAL SAMPLES FROM A DIAGNOSTIC CENTER OF KANPUR
|
|
- Sabina Campbell
- 5 years ago
- Views:
Transcription
1 Original article RETROSPECTIVE STUDY OF GRAM NEGATIVE BACILLI ISOLATES AMONG DIFFERENT CLINICAL SAMPLES FROM A DIAGNOSTIC CENTER OF KANPUR R.Sujatha 1,Nidhi Pal 2, Deepak S 3 1. Professor & Head, Department of Microbiology, Rama Medical college Hospital & research center, Kanpur 2. Ph.D. Scholar, Department of Microbiology, Rama Medical college Hospital & research center, Kanpur 3. PG students, Department of Microbiology, Rama Medical college Hospital & research center, Kanpur ABSTRACT Background: Gram negative bacilli with multiple drug resistance pose a greater risk for potentially untreatable infections with increased morbidity and mortality. Herein, this study was done to know the distribution of gram negative bacilli among different clinical samples and its antibiotic resistance pattern from a diagnostic center of Kanpur. Material &Methods: In this retrospective study, total 655 clinical samples details were taken from previous records of a diagnostic center of Kanpur Results: Among 655 clinical samples, 85.9% urine samples were received followed by pus(7.6%), sputum(3.2%), ear swab (2.2%) and semen (1.1%). E.coli was predominantly isolated from urine samples. K.pneumoniae, P.aeruginosa was commonly isolates from pus and sputum samples respectively. Imipenem and colistin was found to be the most sensitive drug for multidrug resistant gram negative bacilli. 32.1% of P.aeruginosa was found to be ESBL followed by K.pneumonieae (28.7%,), Citrobacter sp.(28.5%) and E.coli(24.5%). Conclusion: Hence to prevent the spread of the resistant bacteria, it is necessary to have antibiogram for hospitals to know the common organisms and their susceptibility patterns. Keywords: Gram negative bacilli, Antibiotic resistant pattern. INTRODUCTION There is numerous microorganism that cause increase morbidity. Among these microorganisms large number of gram negative bacilli belonging particularly to the members of the family Enterobacteriaceae and non-fermenting gram negative bacilli contributes to cause urinary tract infections, respiratory infections, bacteremia and nosocomial infections [1,2]. The major public health problem is increasing antimicrobial resistance among 1
2 gram negative bacilli, which limits the choice of antibiotics. Lack of local antibiotic policy in most of the setting is further exerting a selective antibiotic pressure for selecting out resistant strains [3]. This study was conducted to know distribution of gram negative bacilli among different clinical samples and antibiotic resistant pattern from a diagnostic center of Kanpur. MATERIAL AND METHODS This was a retrospective study, data was collected from a diagnostic center of Kanpur, over a period of six months (December 2016 to May 2017) sample details were recorded. Total 655 positive growth samples were noted. RESULT Among 655 clinical samples, 85.9% urine samples were received followed by pus and sputum. [Table 1] E.coli was the predominant gram negative bacilli followed by K.pneumoniae and P.aeruginosa.[Table 2] E.coli was commonly isolated from urine samples. In pus, K.pneumoniae was predominant isolates and P.aeruginosa was most commonly isolated from sputum samples. Other gram negative bacilli isolation from different samples was mentioned in [Table 3]. Antibiotic resistant pattern of isolated gram negative bacilli was showed in [Table 4]. 32.1% of P.aeruginosa was found to be extended spectrum β- lactamase followed by K.pneumineae, Citrobacter sp. and E.coli of 28.7%, 28.5% and 24.5% respectively [Table 5]. Table 1: Distribution of samples Samples No. of Percent samples (%) Urine Pus Sputum Ear swabs Semen Total 655 Table 2: Distribution of Gram negative bacilli Organism No. of Percent samples (%) E.coli K.pneumoniae P.aeruginosa K.oxytoca Citrobacter
3 Table 3:Distribution of gram negative bacilli among different clinical samples Samples E.coli K.pneumoniae P.aeruginosa K.oxytoca Citrobacter Total Urine Pus Sputum Ear swabs Semen Total Table 4: Antibiotic resistant pattern of gram negative bacilli Antibiotics E.coli N=534 K.pneumoniae N=72 P.aeruginosa N=28 K.oxytoca N=14 Citrobacter sp. N=7 AMP CTX CFS AK GEN CIP COT NIT IPM PB
4 Table 5 ESBL producing Gram negative bacilli Microorganism Percent E.coli 24.5% K.pneumoniae 28.7% P.aeruginosa 32.1% Citrobacter sp. 28.5% DISCUSSION The microbial pathogens, as well as their antibiotic sensitivity patterns may change from time to time and place to place. Members of the family Enterobacteriaceae are among the most important bacterial human pathogens accounting for the majority of bacteria isolated from clinical samples [4]. In our study majority of the Gram negative isolates belonged to enterobacteriacea. Similar results were observed in a study by Balan K et al. [5] and only 4.2% of P.aeruginosa was isolated. In a study by Vipin Kumar et al. [6] 52 (58.42%) isolates of Escherichia coli were found to be the most common organisms followed by Klebsiella pneumoniae 18 (20.22%), Pseudomonas aeruginosa 11 (12.35%), Proteus vulgaris 3 (3.37%), Proteus mirabilis 2 (2.24%), Enterobacter aerogenes 2 (2.24%). Similar results were observed in our study but no Proteus species and Enterobacter aerogenes were isolated. That may be because of less sample population in this study and only diagnostic sample were included. In the present study Carbapenems were found to be most effective drugs against gram negative rods. This was comparable to a study conducted in India which showed the pattern as follows: E. coli (MRP; 95.45% and IMP; 98.45%), P. aeruginosa (MRP; 100% and IMP; 95.00%) [7]. In another study conducted in Iran.othe study showed 91.7% sensitivity against E.coli [8]. E. coli isolates were found to be imipenem (34.42%) resistant, P. aeruginosa (IMP; 42.14%) resistant, results are shown to be highly resistant in our study. K.pneumoniae show 38.06% of resistant for imipenem similarly a study in Saudi Arabia showed about higher resistant [9]. The rise in resistance of organisms to aminoglycosides and amoxicillin in this study may be due to increased consumption. The common form of resistance is mediated by lack of drug penetration (i.e., porin mutations and efflux pumps) and/or carbapenem-hydrolyzing - lactamases. In present study non lactose fermenting isolates, P.aeruginosa showed decreased 4
5 susceptibility to cefotaxime and ceftriazone were defined as extended spectrum β - lactamase (ESBL) phenotypes. Similarly, other gram negative bacilli i.e E.coli, K.pneumoniae and citrobacter species also show ESBL production (24.5%, 28.7% and 28.5% respectively ). No K.oxytoca was produced ESBL enzyme. Thus this study highlights the trends of multidrug resistance among gram negative isolates, therefore indicating an alarm of threat of emergence of drug resistant pathogens CONCLUSION Gram negative isolates are the most common cause of infections. High amount of antibiotic resistance is noted among the isolates. REFERENCES 1. Leng B, Meyers BR, Hirschman SZ, Keusch GT; Susceptibilities of gramnegative bacteria to combinations of antimicrobial agents in vitro.antimicrob. Agents Chemother., 1975; 8(2): Lockhart SR, Abramson MA, Beekmann SE, Gallagher G, Riedel S, Diekema DJ et al.; Antimicrobial Resistance among Gram-Negative Bacilli Causing Infections in Intensive Care Unit Patients in the United States between 1993 and J Clin Microbiol., 2007; 45(10): Antibiogram of clinical isolates from a Healthcare Infection Control Practices Advisory Committee (HICPAC). Central for Disease Control and Prevention (CDC). Management of Multidrug-Resistant Organisms in Healthcare Settings; Available from O/MDROGuideline2006.p df 4. Ekta G, Srujana M, Seema S, Benu D, Bimal KD, Arti K; Emerging resistance to carbapenems in a tertiary care hospital in north India. Indian J Med Res., 2006; 124(1): Balan K, Sujitha K, Vijayalakshmi TS; Antibiotic Susceptibility Pattern of Gram Negative Clinical Isolates in a Teaching Tertiary Care Hospital. Sch J App Med Sci., 2013; 1(2): Vipin K, Rohit K M, Avantika C, Pramila G; Incidence of β-lactamase producing gram-negative clinical isolates and their antibiotic 5
6 susceptibility pattern: A case study in Allahabad. International Journal of Research in Pure and Applied Microbiology, 2011; 1(3): Devanand Prakash and Ramchandra Sahai Saxena. Distribution and Antimicrobial Susceptibility Pattern of Bacterial Pathogens Causing Urinary Tract Infection in Urban Community of Meerut City, India ISRN Microbiology. 2013: Mohammadi MM, Feizabadi M. Antimicrobial resistance pattern of gram-negative bacilli isolated from patients at icus of army hospitals in Iran. Iranian journal of microbiology. 2011;3(1): A. J. Al-Zahran and N. Akhtar. Susceptibility patterns of extended spectrum beta-lactamase (ESBL)- producing Escherichia coli and Klebsiella pneumoniae isolated in a teaching hospital. Pakistan Journal of Medical Research,2005;44: CORRESPONDING AUTHOR: Dr. R.Sujatha Professor and Head of Department of Microbiology Rama Medical College Hospital& Research Centre,Mandhana, Kanpur, U.P. ID: drsujatha152@gmail.com 6
Key words: Urinary tract infection, Antibiotic resistance, E.coli.
Original article MICROBIOLOGICAL STUDY OF URINE ISOLATES IN OUT PATIENTS AND ITS RESISTANCE PATTERN AT A TERTIARY CARE HOSPITAL IN KANPUR. R.Sujatha 1,Deepak S 2, Nidhi P 3, Vaishali S 2, Dilshad K 2 1.
More informationAerobic bacterial infections in a burns unit of Sassoon General Hospital, Pune
Original article Aerobic bacterial infections in a burns unit of Sassoon General Hospital, Pune Patil P, Joshi S, Bharadwaj R. Department of Microbiology, B.J. Medical College, Pune, India. Corresponding
More information2012 ANTIBIOGRAM. Central Zone Former DTHR Sites. Department of Pathology and Laboratory Medicine
2012 ANTIBIOGRAM Central Zone Former DTHR Sites Department of Pathology and Laboratory Medicine Medically Relevant Pathogens Based on Gram Morphology Gram-negative Bacilli Lactose Fermenters Non-lactose
More informationDetection of ESBL Producing Gram Negative Uropathogens and their Antibiotic Resistance Pattern from a Tertiary Care Centre, Bengaluru, India
ISSN: 2319-7706 Volume 4 Number 12 (2015) pp. 578-583 http://www.ijcmas.com Original Research Article Detection of ESBL Producing Gram Negative Uropathogens and their Antibiotic Resistance Pattern from
More informationANTIBIOTIC RESISTANCE OF FLUOROQUINOLONES AMONG THE GRAM NEGATIVE BACTERIAL UROPATHOGENS AT A TERITIARY CARE CENTRE. R.Sujatha 1, Nidhi Pal 2
Original Article ANTIBIOTIC RESISTANCE OF FLUOROQUINOLONES AMONG THE GRAM NEGATIVE BACTERIAL UROPATHOGENS AT A TERITIARY CARE CENTRE R.Sujatha 1, Nidhi Pal 2 1. Professor & Head, Department of Microbiology,
More informationInternational Journal of Pharma and Bio Sciences ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ESBL PRODUCING GRAM NEGATIVE BACILLI ABSTRACT
Research Article Microbiology International Journal of Pharma and Bio Sciences ISSN 0975-6299 ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ESBL PRODUCING GRAM NEGATIVE BACILLI * PRABHAKAR C MAILAPUR, DEEPA
More informationESBL- and carbapenemase-producing microorganisms; state of the art. Laurent POIREL
ESBL- and carbapenemase-producing microorganisms; state of the art Laurent POIREL Medical and Molecular Microbiology Unit Dept of Medicine University of Fribourg Switzerland INSERM U914 «Emerging Resistance
More informationPrevalence of Metallo-Beta-Lactamase Producing Pseudomonas aeruginosa and its antibiogram in a tertiary care centre
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 4 Number 9 (2015) pp. 952-956 http://www.ijcmas.com Original Research Article Prevalence of Metallo-Beta-Lactamase
More informationDetection of Inducible AmpC β-lactamase-producing Gram-Negative Bacteria in a Teaching Tertiary Care Hospital in North India
Original Article Vol. 25 No. 3 Ampc β-lactamase Production in Gram-Negative Bacilli:-Chaudhary U, et al. 129 Detection of Inducible AmpC β-lactamase-producing Gram-Negative Bacteria in a Teaching Tertiary
More informationPrevalence of Extended Spectrum Beta- Lactamase Producers among Various Clinical Samples in a Tertiary Care Hospital: Kurnool District, India
International Journal of Current Microbiology and Applied Sciences ISSN: 319-77 Volume Number (17) pp. 57-3 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/1.5/ijcmas.17..31
More informationESBL Positive E. coli and K. pneumoneae are Emerging as Major Pathogens for Urinary Tract Infection
ESBL Positive E. coli and K. pneumoneae are Emerging as Major Pathogens for Urinary Tract Infection Muhammad Abdur Rahim*, Palash Mitra*. Tabassum Samad*. Tufayel Ahmed Chowdhury*. Mehruba Alam Ananna*.
More informationESBL Producers An Increasing Problem: An Overview Of An Underrated Threat
ESBL Producers An Increasing Problem: An Overview Of An Underrated Threat Hicham Ezzat Professor of Microbiology and Immunology Cairo University Introduction 1 Since the 1980s there have been dramatic
More informationA retrospective analysis of urine culture results issued by the microbiology department, Teaching Hospital, Karapitiya
A retrospective analysis of urine culture results issued by the microbiology department, Teaching Hospital, Karapitiya LU Edirisinghe 1, D Vidanagama 2 1 Senior Registrar in Medicine, 2 Consultant Microbiologist,
More informationPrevalence of Extended-spectrum β-lactamase Producing Enterobacteriaceae Strains in Latvia
Prevalence of Extended-spectrum β-lactamase Producing Enterobacteriaceae Strains in Latvia Ruta Paberza 1, Solvita Selderiņa 1, Sandra Leja 1, Jelena Storoženko 1, Lilija Lužbinska 1, Aija Žileviča 2*
More informationAntimicrobial Cycling. Donald E Low University of Toronto
Antimicrobial Cycling Donald E Low University of Toronto Bad Bugs, No Drugs 1 The Antimicrobial Availability Task Force of the IDSA 1 identified as particularly problematic pathogens A. baumannii and
More informationAntimicrobial resistance at different levels of health-care services in Nepal
Antimicrobial resistance at different levels of health-care services in Nepal K K Kafle* and BM Pokhrel** Abstract Infectious diseases are major health problems in Nepal. Antimicrobial resistance (AMR)
More informationBacterial Pathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern from a Teaching Hospital, Bengaluru, India
ISSN: 2319-7706 Volume 4 Number 11 (2015) pp. 731-736 http://www.ijcmas.com Original Research Article Bacterial Pathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern from a Teaching
More informationComparison of Antibiotic Resistance and Sensitivity with Reference to Ages of Elders
Daffodil International University Institutional Repository DIU Journal of Science and Technology Volume 10, Issue 1-2, July 2015 2016-06-16 Comparison of Antibiotic Resistance and Sensitivity with Reference
More informationInt.J.Curr.Microbiol.App.Sci (2017) 6(3):
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 3 (2017) pp. 891-895 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2017.603.104
More informationSamantha Trumm, Pharm.D. PGY-1 Resident Avera McKennan Hospital and University Center
Samantha Trumm, Pharm.D. PGY-1 Resident Avera McKennan Hospital and University Center I have had no financial relationship over the past 12 months with any commercial sponsor with a vested interest in
More informationIntrinsic, implied and default resistance
Appendix A Intrinsic, implied and default resistance Magiorakos et al. [1] and CLSI [2] are our primary sources of information on intrinsic resistance. Sanford et al. [3] and Gilbert et al. [4] have been
More informationAntimicrobial susceptibility
Antimicrobial susceptibility PATTERNS Microbiology Department Canterbury ealth Laboratories and Clinical Pharmacology Department Canterbury District ealth Board March 2011 Contents Preface... Page 1 ANTIMICROBIAL
More informationInternationally indexed journal
www.ijpbs.net Internationally indexed journal Indexed in Chemical Abstract Services (USA), Index coppernicus, Ulrichs Directory of Periodicals, Google scholar, CABI,DOAJ, PSOAR, EBSCO, Open J gate, Proquest,
More information2009 ANTIBIOGRAM. University of Alberta Hospital and the Stollery Childrens Hospital
2009 ANTIBIOGRAM University of Alberta Hospital and the Stollery Childrens Hospital Division of Medical Microbiology Department of Laboratory Medicine and Pathology 2 Table of Contents Page Introduction.....
More informationInternational Journal of Health Sciences and Research ISSN:
International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Original Research Article Antibiotic Susceptibility Pattern of Pseudomonas Aeruginosa Isolated From Various Clinical
More informationInternational Journal of Pharma and Bio Sciences
Research Article Microbiology International Journal of Pharma and Bio Sciences ISSN 0975-6299 PREVALENCE OF EXTENDED SPECTRUM BETA LACTAMASES AMONG GRAM NEGATIVE CLINICAL ISOLATES FROM A TERTIARY CARE
More information2015 Antibiogram. Red Deer Regional Hospital. Central Zone. Alberta Health Services
2015 Antibiogram Red Deer Regional Hospital Central Zone Alberta Health Services Introduction. This antibiogram is a cumulative report of the antimicrobial susceptibility rates of common microbial pathogens
More informationAvailable online at ISSN No:
Available online at www.ijmrhs.com ISSN No: 2319-5886 International Journal of Medical Research & Health Sciences, 2017, 6(4): 36-42 Comparative Evaluation of In-Vitro Doripenem Susceptibility with Other
More information2015 Antimicrobial Susceptibility Report
Gram negative Sepsis Outcome Programme (GNSOP) 2015 Antimicrobial Susceptibility Report Prepared by A/Professor Thomas Gottlieb Concord Hospital Sydney Jan Bell The University of Adelaide Adelaide On behalf
More informationDo clinical microbiology laboratory data distort the picture of antibiotic resistance in humans and domestic animals?
Do clinical microbiology laboratory data distort the picture of antibiotic resistance in humans and domestic animals? Scott Weissman, MD 2 June 2018 scott.weissman@seattlechildrens.org Disclosures I have
More informationPrevalenceofAntimicrobialResistanceamongGramNegativeIsolatesinanAdultIntensiveCareUnitataTertiaryCareCenterinSaudiArabia
: K Interdisciplinary Volume 17 Issue 4 Version 1.0 Year 2017 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Inc. (USA) Online ISSN: 2249-4618 & Print ISSN:
More informationMili Rani Saha and Sanya Tahmina Jhora. Department of Microbiology, Sir Salimullah Medical College, Mitford, Dhaka, Bangladesh
Detection of extended spectrum beta-lactamase producing Gram-negative organisms: hospital prevalence and comparison of double disc synergy and E-test methods Mili Rani Saha and Sanya Tahmina Jhora Original
More information2010 ANTIBIOGRAM. University of Alberta Hospital and the Stollery Children s Hospital
2010 ANTIBIOGRAM University of Alberta Hospital and the Stollery Children s Hospital Medical Microbiology Department of Laboratory Medicine and Pathology Table of Contents Page Introduction..... 2 Antibiogram
More informationJMSCR Vol. 03 Issue 08 Page August 2015
www.jmscr.igmpublication.org Impact Factor 3.79 ISSN (e)-2347-176x DOI: http://dx.doi.org/10.18535/jmscr/v3i8.07 Isolation of Extended Spectrum Β-Lactamases in Urine Samples Authors Sukesh Kumar B Y 1,
More informationMulti-drug resistant microorganisms
Multi-drug resistant microorganisms Arzu TOPELI Director of MICU Hacettepe University Faculty of Medicine, Ankara-Turkey Council Member of WFSICCM Deaths in the US declined by 220 per 100,000 with the
More informationMechanism of antibiotic resistance
Mechanism of antibiotic resistance Dr.Siriwoot Sookkhee Ph.D (Biopharmaceutics) Department of Microbiology Faculty of Medicine, Chiang Mai University Antibiotic resistance Cross-resistance : resistance
More informationMono- versus Bitherapy for Management of HAP/VAP in the ICU
Mono- versus Bitherapy for Management of HAP/VAP in the ICU Jean Chastre, www.reamedpitie.com Conflicts of interest: Consulting or Lecture fees: Nektar-Bayer, Pfizer, Brahms, Sanofi- Aventis, Janssen-Cilag,
More informationGENERAL NOTES: 2016 site of infection type of organism location of the patient
GENERAL NOTES: This is a summary of the antibiotic sensitivity profile of clinical isolates recovered at AIIMS Bhopal Hospital during the year 2016. However, for organisms in which < 30 isolates were recovered
More informationESCMID Online Lecture Library. by author
Expert rules in susceptibility testing EUCAST-ESGARS-EPASG Educational Workshop Linz, 16 19 September, 2014 Dr. Rafael Cantón Hospital Universitario Ramón y Cajal SERVICIO DE MICROBIOLOGÍA Y PARASITOLOGÍA
More informationSafe Patient Care Keeping our Residents Safe Use Standard Precautions for ALL Residents at ALL times
Safe Patient Care Keeping our Residents Safe 2016 Use Standard Precautions for ALL Residents at ALL times #safepatientcare Do bugs need drugs? Dr Deirdre O Brien Consultant Microbiologist Mercy University
More informationDr Vivien CHUANG Associate Consultant Infection Control Branch, Centre for Health Protection/ Infectious Disease Control and Training Center,
Dr Vivien CHUANG Associate Consultant Infection Control Branch, Centre for Health Protection/ Infectious Disease Control and Training Center, Hospital Authority NDM-1, which stands for New Delhi Metallo-beta-lactamase-1
More informationIsolation of Urinary Tract Pathogens and Study of their Drug Susceptibility Patterns
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 4 (2016) pp. 897-903 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.504.101
More informationBACTERIOLOGICALL STUDY OF MICROORGANISMS ON MOBILES AND STETHOSCOPES USED BY HEALTH CARE WORKERS IN EMERGENCY AND ICU S
Research Article Harika A,, 2013; Volume 2(3): 290-297 ISSN: 2277-8713 BACTERIOLOGICALL STUDY OF MICROORGANISMS ON MOBILES AND STETHOSCOPES USED BY HEALTH CARE WORKERS IN EMERGENCY AND ICU S HARIKAA A,
More informationEXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) TESTING
EXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) TESTING CHN61: EXTENDED-SPECTRUM BETA-LACTAMASE (ESBL) TESTING 1.1 Introduction A common mechanism of bacterial resistance to beta-lactam antibiotics is the production
More informationAntimicrobial Stewardship Strategy: Antibiograms
Antimicrobial Stewardship Strategy: Antibiograms A summary of the cumulative susceptibility of bacterial isolates to formulary antibiotics in a given institution or region. Its main functions are to guide
More information2017 Antibiogram. Central Zone. Alberta Health Services. including. Red Deer Regional Hospital. St. Mary s Hospital, Camrose
2017 Antibiogram Central Zone Alberta Health Services including Red Deer Regional Hospital St. Mary s Hospital, Camrose Introduction This antibiogram is a cumulative report of the antimicrobial susceptibility
More informationAerobic Bacterial Profile and Antimicrobial Susceptibility Pattern of Pus Isolates in a Tertiary Care Hospital in Hadoti Region
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 5 (2017) pp. 2866-2873 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2017.605.326
More informationAberdeen Hospital. Antibiotic Susceptibility Patterns For Commonly Isolated Organisms For 2015
Aberdeen Hospital Antibiotic Susceptibility Patterns For Commonly Isolated s For 2015 Services Laboratory Microbiology Department Aberdeen Hospital Nova Scotia Health Authority 835 East River Road New
More informationSurveillance of Antimicrobial Resistance among Bacterial Pathogens Isolated from Hospitalized Patients at Chiang Mai University Hospital,
Original Article Vol. 28 No. 1 Surveillance of Antimicrobial Resistance:- Chaiwarith R, et al. 3 Surveillance of Antimicrobial Resistance among Bacterial Pathogens Isolated from Hospitalized Patients at
More informationIrrational use of antimicrobial agents often
Antibiotic Resistance of Isolated Bacteria in 1 and Abdo-Rabbo A. 2 Irrational use of antimicrobial agents often leads to the multi-drug resistance microorganisms. This study is aimed at investigating
More informationAn evaluation of the susceptibility patterns of Gram-negative organisms isolated in cancer centres with aminoglycoside usage
Journal of Antimicrobial Chemotherapy (1991) 27, Suppl. C, 1-7 An evaluation of the susceptibility patterns of Gram-negative organisms isolated in cancer centres with aminoglycoside usage J. J. Muscato",
More informationJOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH How to cite this article: SHOBHA K L, RAMACHANDRA L, RAO G, MAJUMDER S, RAO S P. EXTENDED SPECTRUM BETA-LACTAMASES (ESBL) IN GRAM NEGATIVE BACILLI AT A TERTIARY
More informationLearning Points. Raymond Blum, M.D. Antimicrobial resistance among gram-negative pathogens is increasing
Raymond Blum, M.D. Learning Points Antimicrobial resistance among gram-negative pathogens is increasing Infection with antimicrobial-resistant pathogens is associated with increased mortality, length of
More informationAntimicrobial Susceptibility Profile of E. coli Isolates Causing Urosepsis: Single Centre Experience
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 05 (2018) Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2018.705.298
More informationAppropriate antimicrobial therapy in HAP: What does this mean?
Appropriate antimicrobial therapy in HAP: What does this mean? Jaehee Lee, M.D. Kyungpook National University Hospital, Korea KNUH since 1907 Presentation outline Empiric antimicrobial choice: right spectrum,
More informationStudy of Bacteriological Profile of Corneal Ulcers in Patients Attending VIMS, Ballari, India
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 7 (2016) pp. 200-205 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.507.020
More informationSepsis is the most common cause of death in
ADDRESSING ANTIMICROBIAL RESISTANCE IN THE INTENSIVE CARE UNIT * John P. Quinn, MD ABSTRACT Two of the more common strategies for optimizing antimicrobial therapy in the intensive care unit (ICU) are antibiotic
More informationFlorida Health Care Association District 2 January 13, 2015 A.C. Burke, MA, CIC
Florida Health Care Association District 2 January 13, 2015 A.C. Burke, MA, CIC 11/20/2014 1 To describe carbapenem-resistant Enterobacteriaceae. To identify laboratory detection standards for carbapenem-resistant
More informationESBL producing GNBs in burn wound infections An alarming situation
Original article: ESBL producing GNBs in burn wound infections An alarming situation Vishakha Shikhare, Pranita Palekar, Neeta Jangale, Meena Ramteerthakar, Pankaj Joshi Department of Microbiology, Govt.
More information2016 Antibiogram. Central Zone. Alberta Health Services. including. Red Deer Regional Hospital. St. Mary s Hospital, Camrose
2016 Antibiogram Central Zone Alberta Health Services including Red Deer Regional Hospital St. Mary s Hospital, Camrose Introduction This antibiogram is a cumulative report of the antimicrobial susceptibility
More informationEnterobacter aerogenes
Enterobacter aerogenes Enterobacter sp. Enterobacter sp. Species: Enterobacter aerogenes Enterobacter agglomerans Enterobacter cloacae causes UTI, enterotoxigenic Often found in the normal intestinal flora,
More informationINCIDENCE OF BACTERIAL COLONISATION IN HOSPITALISED PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS
INCIDENCE OF BACTERIAL COLONISATION IN HOSPITALISED PATIENTS WITH DRUG-RESISTANT TUBERCULOSIS 1 Research Associate, Drug Utilisation Research Unit, Nelson Mandela University 2 Human Sciences Research Council,
More informationOccurrence of Extended-Spectrum Beta-Lactamases Among Blood Culture Isolates of Gram-Negative Bacteria
Original Article Vol. 21 No. 2 ESBL producers among blood culture isolates:- Kapoor L, Deb M. 53 Occurrence of Extended-Spectrum Beta-Lactamases Among Blood Culture Isolates of Gram-Negative Bacteria Lata
More informationA hospital based surveillance of metallo beta lactamase producing gram negative bacteria in Nepal by imipenem EDTA disk method
DOI 10.1186/s13104-017-2640-7 BMC Research Notes RESEARCH ARTICLE Open Access A hospital based surveillance of metallo beta lactamase producing gram negative bacteria in Nepal by imipenem EDTA disk method
More informationComparative Assessment of b-lactamases Produced by Multidrug Resistant Bacteria
Comparative Assessment of b-lactamases Produced by Multidrug Resistant Bacteria Juhee Ahn Department of Medical Biomaterials Engineering Kangwon National University October 23, 27 Antibiotic Development
More informationHospital ID: 831. Bourguiba Hospital. Tertiary hospital
Global Point Prevalence Survey of Antimicrobial Consumption and Resistance in hospitals worldwide Hospital ID: 831 Habib Bourguiba Hospital Tertiary hospital Tunisia Point Prevalence Survey Habib 2017
More informationDR. MICHAEL A. BORG DIRECTOR OF INFECTION PREVENTION & CONTROL MATER DEI HOSPITAL - MALTA
DR. MICHAEL A. BORG DIRECTOR OF INFECTION PREVENTION & CONTROL MATER DEI HOSPITAL - MALTA The good old days The dread (of) infections that used to rage through the whole communities is muted Their retreat
More informationETHIOLOGICAL AND THERAPEUTICAL PARTICULARITIES OF URINARY INFECTIONS IN UROLOGICAL PATIENTS
Bulletin of the Transilvania University of Braşov Series VI: Medical Sciences Vol. 7 (56) No. 1-2014 ETHIOLOGICAL AND THERAPEUTICAL PARTICULARITIES OF URINARY INFECTIONS IN UROLOGICAL PATIENTS G.G. MATEESCU
More informationBLA-NDM-1 IN CLINICAL ISOLATES OF Acinetobacter baumannii FROM NORTH INDIA
ISSN: 0976-2876 (Print) ISSN: 2250-0138(Online) BLA-NDM-1 IN CLINICAL ISOLATES OF Acinetobacter baumannii FROM NORTH INDIA NIDHI PAL a, R. SUJATHA b AND ANIL KUMAR 1c a Department of Microbiology, Rama
More informationPreventing Multi-Drug Resistant Organism (MDRO) Infections. For National Patient Safety Goal
Preventing Multi-Drug Resistant Organism (MDRO) Infections For National Patient Safety Goal 07.03.01 2009 Methicillin Resistant Staphlococcus aureus (MRSA) About 3-8% of the population at large is a carrier
More informationStudy of drug resistance pattern of principal ESBL producing urinary isolates in an urban hospital setting in Eastern India
Research article Study of drug resistance pattern of principal ESBL producing urinary isolates in an urban hospital setting in Eastern India Mitali Chatterjee, 1 M. Banerjee, 1 S. Guha, 2 A.Lahiri, 3 K.Karak
More informationMicrobiology. Multi-Drug-Resistant bacteria / MDR: laboratory diagnostics and prevention. Antimicrobial resistance / MDR:
Microbiology Multi-Drug-Resistant bacteria / MDR: laboratory diagnostics and prevention June 2017 MeshHp (VS) Medical Care Center Dr. Eberhard & Partner Dortmund (ÜBAG) www.labmed.de MVZ Dr. Eberhard &
More information2016, Maxwell Scientific Publication Corp. Submitted: March 12, 2011 Accepted: June 5, 2016 Published: June 25, 2016
Asian Journal of Medical Sciences 8(2): 5-9, 216 DOI:1.1926/ajms.8.2914 ISSN: 24-8765; e-issn: 24-8773 216, Maxwell Scientific Publication Corp. Submitted: March 12, 211 Accepted: June 5, 216 Published:
More informationBacteriological Study of Catheter Associated Urinary Tract Infection in a Tertiary Care Hospital
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 9 (2016) pp. 640-644 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.509.073
More informationComparison of Susceptibility of Gram Negative Bacilli to Cephalosporins and Ciprofloxacin
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 9 (2016) pp. 205-212 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.509.023
More informationCONTAGIOUS COMMENTS Department of Epidemiology
VOLUME XXIII NUMBER 1 July 2008 CONTAGIOUS COMMENTS Department of Epidemiology Bugs and Drugs Elaine Dowell, SM (ASCP), Marti Roe SM (ASCP), Ann-Christine Nyquist MD, MSPH Are the bugs winning? The 2007
More informationReport on the APUA Educational Symposium: "Facing the Next Pandemic of Pan-resistant Gram-negative Bacilli"
Preserving the Power of Antibiotics Report on the APUA Educational Symposium: "Facing the Next Pandemic of Pan-resistant Gram-negative Bacilli" Held on Thursday, September 30, 2004 in Boston, MA Preceding
More informationAntibiotic utilization and Pseudomonas aeruginosa resistance in intensive care units
NEW MICROBIOLOGICA, 34, 291-298, 2011 Antibiotic utilization and Pseudomonas aeruginosa resistance in intensive care units Vladimíra Vojtová 1, Milan Kolář 2, Kristýna Hricová 2, Radek Uvízl 3, Jan Neiser
More informationDetection of ESBL, MBL and MRSA among Isolates of Chronic Osteomyelitis and their Antibiogram
ISSN: 2319-7706 Volume 4 Number 10 (2015) pp. 289-295 http://www.ijcmas.com Original Research Article Detection of ESBL, MBL and MRSA among Isolates of Chronic Osteomyelitis and their Antibiogram Mita
More informationA Study on Bacterial Flora on the Finger printing Surface of the Biometric Devices at a Tertiary Care Hospital
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 9 (2016) pp. 441-446 Journal homepage: http://www.ijcmas.com Original Research Article http://dx.doi.org/10.20546/ijcmas.2016.509.047
More informationOriginal Articles. K A M S W Gunarathne 1, M Akbar 2, K Karunarathne 3, JRS de Silva 4. Sri Lanka Journal of Child Health, 2011; 40(4):
Original Articles Analysis of blood/tracheal culture results to assess common pathogens and pattern of antibiotic resistance at medical intensive care unit, Lady Ridgeway Hospital for Children K A M S
More informationAntibiogram of Bacterial Isolates at Hail General Hospital, KSA June 1 December 31, 2012
IOSR Journal of Nursing and Health Science (IOSR-JNHS) e-issn: 2320 1959.p- ISSN: 2320 1940 Volume 4, Issue 1 Ver. I (Jan.-Feb. 2015), PP 21-26 www.iosrjournals.org Antibiogram of Bacterial Isolates at
More informationConcise Antibiogram Toolkit Background
Background This toolkit is designed to guide nursing homes in creating their own antibiograms, an important tool for guiding empiric antimicrobial therapy. Information about antibiograms and instructions
More informationManagement of Hospital-acquired Pneumonia
Management of Hospital-acquired Pneumonia Adel Alothman, MB, FRCPC, FACP Asst. Professor, COM, KSAU-HS Head, Infectious Diseases, Department of Medicine King Abdulaziz Medical City Riyadh Saudi Arabia
More informationRise of Resistance: From MRSA to CRE
Rise of Resistance: From MRSA to CRE Paul D. Holtom, MD Professor of Medicine and Orthopaedics USC Keck School of Medicine SUPERBUGS (AKA MDROs) MRSA Methicillin-resistant S. aureus Evolution of Drug Resistance
More informationAntimicrobial Susceptibility Patterns of Salmonella Typhi From Kigali,
In the name of God Shiraz E-Medical Journal Vol. 11, No. 3, July 2010 http://semj.sums.ac.ir/vol11/jul2010/88030.htm Antimicrobial Susceptibility Patterns of Salmonella Typhi From Kigali, Rwanda. Ashok
More informationOther Enterobacteriaceae
GUIDE TO INFECTION CONTROL IN THE HOSPITAL CHAPTER NUMBER 50: Other Enterobacteriaceae Author Kalisvar Marimuthu, MD Chapter Editor Michelle Doll, MD, MPH Topic Outline Topic outline - Key Issues Known
More informationSaudi Journal of Pathology and Microbiology (SJPM)
Saudi Journal of Pathology and Microbiology (SJPM) Scholars Middle East Publishers Dubai, United Arab Emirates Website: http://scholarsmepub.com/ ISSN 2518-3362 (Print) ISSN 2518-3370 (Online) A Prevalence
More informationCarbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S
Carbapenemase-producing Enterobacteriaceae (CRE) T H E L A T E S T I N T H E G R O W I N G L I S T O F S U P E R B U G S CRE Enterobacteriaceae (Gram Negative Bacilli) Citrobacter species Escherichia coli***
More information9/30/2016. Dr. Janell Mayer, Pharm.D., CGP, BCPS Dr. Lindsey Votaw, Pharm.D., CGP, BCPS
Dr. Janell Mayer, Pharm.D., CGP, BCPS Dr. Lindsey Votaw, Pharm.D., CGP, BCPS 1 2 Untoward Effects of Antibiotics Antibiotic resistance Adverse drug events (ADEs) Hypersensitivity/allergy Drug side effects
More informationCommunity-Acquired Urinary Tract Infection. (Etiology and Bacterial Susceptibility)
ISSN 222-28 (Paper) ISSN 222-9X (Online) Community-Acquired Urinary Tract Infection (Etiology and Bacterial Susceptibility) Nawal S Faris Department of Allied medical sciences /Zarqa University) ABSTRACT
More informationSummary of the latest data on antibiotic resistance in the European Union
Summary of the latest data on antibiotic resistance in the European Union EARS-Net surveillance data November 2017 For most bacteria reported to the European Antimicrobial Resistance Surveillance Network
More informationSouth As. J. Biol. Sci. 2(Supp.1): ISSN
South As. J. Biol. Sci. 2(Supp.1):140-149 ISSN 2249-6599 Phenotypic Characterization of Urinary Tract Infection Causing Escherichia coli in Paediatric age group along with Prevalence of Extended Spectrum
More informationUK Journal of Pharmaceutical and Biosciences Available at ISSN:
UK Journal of Pharmaceutical and Biosciences Vol. 5(2), 45-49, 2017 RESEARCH ARTICLE UK Journal of Pharmaceutical and Biosciences Available at www.ukjpb.com ISSN: 2347-9442 Anti-Microbial Susceptibility
More informationInvestigated of ampc in Carbapenem Resistant Gram-Negative Bacteria Isolated from Burned Patients
Investigated of ampc in Carbapenem Resistant Gram-Negative Bacteria Isolated from Burned Patients Leila Azimi 1, 2, Malihe Talebi 2, Parviz Owlia 3, Abdolaziz Rastegar Lari 1, 2 * 1 Antimicrobial Resistance
More informationChemotherapy of bacterial infections. Part II. Mechanisms of Resistance. evolution of antimicrobial resistance
Chemotherapy of bacterial infections. Part II. Mechanisms of Resistance evolution of antimicrobial resistance Mechanism of bacterial genetic variability Point mutations may occur in a nucleotide base pair,
More informationClinico-Microbiological Profile of Urinary Tract Infection in Tertiary Care Hospital in Ahmedabad, Gujarat, India
ISSN: 2319-7706 Volume 4 Number 9 (2015) pp. 288-295 http://www.ijcmas.com Original Research Article Clinico-Microbiological Profile of Urinary Tract Infection in Tertiary Care Hospital in Ahmedabad, Gujarat,
More informationWitchcraft for Gram negatives
Witchcraft for Gram negatives Dr Subramanian S MD DNB MNAMS AB (Medicine, Infect Dis) Infectious Diseases Consultant Global Health City, Chennai www.asksubra.com Drug resistance follows the drug like a
More informationEpidemiology and Burden of Antimicrobial-Resistant P. aeruginosa Infections
Epidemiology and Burden of Antimicrobial-Resistant P. aeruginosa Infections Keith S. Kaye, MD, MPH Professor of Medicine Division of Infectious Diseases Department of Internal Medicine University of Michigan
More informationImagine. Multi-Drug Resistant Superbugs- What s the Big Deal? A World. Without Antibiotics. Where Simple Infections can be Life Threatening
Multi-Drug Resistant Superbugs- What s the Big Deal? Toni Biasi, RN MSN MPH CIC Infection Prevention Indiana University Health Imagine A World Without Antibiotics A World Where Simple Infections can be
More information