CEVA products for reproduction management

Transcription

1 CEVA products for reproduction management 1

2 Prostaglandin ENZAPROST-T A complete range of products GnRH Ovarelin (Cystorelin) Prid Delta

3 Suitable for different protocols Synchronization programs for beef and dairy Cows and heifers Flexibility to have products to couple with ANY management situation

4 A complete range of products Prostaglandin ENZAPROST-T Uterotonic and luteolytic effect, naturally

5 ENZAPROST T - Product profile Synthetic PGF2α: Dinoprost tromethamine salt Composition : 5 mg/ml Dosage : intramuscular injection Cattle : 25 mg (5ml)

6 Indications Oestrus synchronisation Treatment of sub-oestrus or silent heat in cows which have a functional CL Induction of abortion until day 120 of pregnancy Induction of parturition For the aid in the treatment of chronic metritis or pyometra

7 Pre-synch programs: Enzaprost: novel uses in reproductive programs

8 A complete range of products GnRH OVARELIN (Cystorelin) Improved conception rate at single dose

9 Cystoreline: Product Profile Compound : synthetic GnRH, gonadorelin as diacetate tetrahydrate 50 µg / ml Dosage : Cattle = 100 µg (2 ml) Intramuscular route Indications : Treatment of delayed ovulation (repeat breeding RBS). A repeat breeder cow is an animal that has been inseminated at least 2-3 times without becoming pregnant, despite having regular normal œstrus cycles, normal œstrus behaviour and no clinical abnormalities of the reproductive tract.

10 Features & Benefits FEATURES Induce the release of a LH surge BENEFITS Induction of ovulation Precises ovulation timing : improvement of fertility Prevents delayed ovulation (in RBS) Use in synchronisation programs Treatment of ovarian cysts Low molecular weight Synthetically produced Non antigenic : no refractoriness nor anaphylaxis Uniformity of potency

11 Protocol : Fertility improvement Oestrus 12 days OVARELIN Improves fertility OVARELIN Reduces embtyonic mortality Results : GnRH injection At the time of insemination At AI and 12 days later 1289 dairy cows during summer in Spain Treatment N Pregnancy rate Placebo % GnRH at AI % GnRH at AI + D % F. LOPEZ-GATIUS

12 Novel uses of GnRH: Pre-synch programs (1 st and 2 nd AI) GnRH PGF2 GnRH GnRH PGF2 GnRH Timed AI 7 days 3 days 7 days 7 days 56h 16h Day 0 8AM Day 7 8AM Day 10 4PM Day 17 8AM Day 24 8AM Day 26 4PM Day 27 8AM Ovsynch-1: to get cows at right time to the second Ovsynch Ovsynch-2

13 A complete range of products Progesterone Releasing Intravaginal Device PRID DELTA Optimum fertility for profitable reproduction

14 PRID DELTA Innovation: bi-material device polyethylene spin inert elastomer : EVA (Ethyl Vinyl Acetate) 1.55 g of natural progesterone Delta shape : unique Good contact Proper retention Comfort of animals

15 Applicator PRID Delta does not require any special technique : X1

16 Prid Delta Protocol OVARELİN ENZAPROST T 7 9 days 56 hours Insertion Prid Withdrawal AI* * 48 and 72 hours if 2 AI

17 Novel uses of P4 devices: short 5d-protocols Synchronisation of oestrus and ovulation in heifers/cows Treatment of anoestrus in cows and heifers Cystoreline D0 8AM PRID-Delta for 5 days Enzaprost* D5 8AM 2 nd Enzaprost 24h later D6 8AM GnRH + AI 72h after device removal D8 8AM

18

19 Anti-Infective Injectable Range Ceva individual product characteristics

20 CEVAXEL RTU ceftiofur 50mg/ml Cephalosporin 3G claim, dosage and withdrawal period: For the treatment of bacterial respiratory disease associated with Pasteurella multocida, Mannheimia haemolytica and Haemophilus somnus. For the treatment of acute interdigital necrobacillosis (panaritium, foot rot), associated with Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica). For treatment of the bacterial component of acute post-partum (puerperal) metritis within 10 days after calving associated with Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum. dosage is 1 mg/kg/day SC for 3 to 5 days, i.e. 1 ml/50 kg at each injection WP: meat and offal: 8 days - milk : 0 hours 10-12Days 0 hours 20

21 VETRIMOXIN L.A. amoxicillin 150mg/ml Penicillin group A claim, dosage and withdrawal period: Diseases due to pathogens sensitive to amoxicillin Treatment of respiratory infections due to Gram positive bacteria or pasteurellae (F.) dosage is 15 mg/kg bodyweight i.e. 1 ml/10 kg bw twice 2 days apart IM WP: meat and offal: 14 days - milk : 2 days (F.) Competitors WP : Clamoxyl LA meat and offal 92 days, milk 9 days, 16 days 3 Days 21

22 SPIROVET spiramycin UI/ml Macrolide claim, dosage and withdrawal period: - treatment of infective BRD, mastitis, metritis, footrot (F.) Dosage: Cattle: UI/kg bw IM with possible second injection 24 hours apart, i.e. 5 ml/100 kg bw per injection* WP: meat and offal: 52 days - milk: 7 days (F.) 52 Days 7 Days * Possibly second injection 24 h later 22