Therapeutic efficacy of a mixture of ivermectin and closantel against gastrointestinal parasites in draft horses
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1 ( - ) ( ) % %15.75 Oxyuris equi % 1.58 Strongylus spp..% / 0.05.% Parascaris equorum Parascaris equorum % Strongylus spp. % Oxyuris equi.gastrophilus nasalis Therapeutic efficacy of a mixture of ivermectin and closantel against gastrointestinal parasites in draft horses Abstract M. K. Aldelami and B. A. Albadrani Department of Internal and Preventative Medicine, College of Veterinary Medicine, University of Mosul, Mosul, Iraq Examination of 19 fecal samples showed positive results for nematodes. It was classified as a single and mixed infestation 58.0% and 42.1% respectively. The percentages of infestation with Strongylus spp, Oxyuris equi and Parascaris equorum were 1.58%, 15.75%, 10.52% respectively. Administration of a single dose of mixture of ivermectin and closantel (0.05 ml/kg body weight) revealed a significant reduction in average egg count in feces of the treated horses with both single and mixed infection. Efficacy of mixture of ivermectin and closantel for was 100% in removing eggs of the Parascaris equorm and Oxyuris equi and 99.42% for Strongylus spp at 14 days post-treatment. The preparation was also effective in removing larvae of Gastrophilus nasalis. Available online at ) (.( ) / IVERTEL closantel Ivermectin " ٣٧
2 ( - ).( ) 28 2 MacMaster 5 : / ).( ) (50 X 2 EDTA ( ) /.( ) 11) ( 8) (. / McMaster : (معدل أعداد البيوض في اليوم صفر"قبل العلاج" معدل أعداد البيوض "بعد العلاج") 100 X معدل أعداد البيوض في اليوم صفر"قبل العلاج" Paired Students' t test., ) % Strongylus Oxyuris equi Strongylus.( ) westrei Salicylinide Fasciola hepatica Trematodes.( ) Fasciola gigantica Gastrophilus S. S. vulgaris nasalis ( ) ( ) S. edentatus vulgaris Strongylus 100 L4 %.( ) / 8 ( ). 0 ( ) (8 1.5). 0 ) ( ).( ) ٣٨
3 ( - ) : % 95 % %. %. % Oxyuris equi Parascaris equorum % % 100 Strongylus spp. % % ( ) % 19 8 (% 58.0) 11. (% 42.1) equi Oxyuris(% 1.58) Strongylus 10.5) Parascaris equorum (%15.8).(% Strongylus Strongylus equi Oxyuris Parascaris equorum Gastrophilus westrei % 10.5 nasalis ( 11). ).(1.( 28) (P<0.05) ( ) ( ) ٣٩
4 ( - ) Strongylus spp 0.60 ( 100/ ) ( 100/ ) / 6 10 x / 6 10 x / 6 10 x 6.2 Strongylus spp 0.28 / 6 10 x 5.82.Oxyuris equi 2.05 / 10 x / 10 x 7.58 Strongylus spp 1.9 / 10 x / 10 x 7.00.Oxyuris equi ( / ) Oxyuris equi ( / ) ( ).( ) : ( /, ) / * * ).( ( ) *.(P<0.05).Strongylus spp (P<0.05) / : * 0* 27. * 26* Strongylus spp. (% 100) (% 100) (% 99.4) (% 95.0) % 150.0* * 0* 0* Parascaris % equorum (% 100) (% 100) (% 100) (% 98.62) 0* 0* 0* 60.00* Oxyuris equi (% 100) (% 100) (% 100) (% 98.88) %.(P<0.05) ( ) * ٤٠
5 ( - ). Parascaris Strongylus spp. Oxyuris equi equorum / 64.. / Strongylus spp. % 100 Strongylus spp..( ) Parascaris Strongylus spp..() % 100 Oxyuris equi equorum.( ) ( ).. 1. Adams HR. Veterinary Pharmacology and Therapeutics. 8 th ed. Iowa State Press, A Blackwell publish Company 2001: Hutchens DE, Paul AJ, Dipietro JA. Treatment and control of gastrointestinal parasites. Vet Clin North Am.: Equine Pract : ( ) ( ).(). Strongylus Oxyuris equi Parascaris equorum spp. Oxyuris ( ) equi ( ).( ) Strongylus spp..( ).( ) 4 ( ) ٤١
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