Evaluation of intervention strategies for subclinical and clinical mastitis

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1 Evaluation of intervention strategies for subclinical and clinical mastitis CPH Cattle seminar, 31. October 2018 Maya Gussmann, Wilma Steeneveld, Carsten Kirkeby, Henk Hogeveen, Michael Farre, Tariq Halasa

2 Objective Identify cost-effective intervention strategies for subclinical and clinical mastitis 2

3 The model: Simulating a dairy herd Lactating cows Dry cows Heifers Calves Calving area 3

4 The model: Simulating IMI S. agalactiae Opportunistic pathogens Contagious pathogens S. aureus S. uberis Environmental pathogens E. coli S. uberis 4

5 The model: Simulating IMI 5

6 The model: Simulating consequences of IMI Somatic Cell Count Milk yield Treatment of clinical Dry cow treatment Culling probability 6

7 Simulating clinical IMI interventions 3 day intramammary treatment Reactive culling: Testing before treatment, estimate recovery probability, cull cows with low probability (<50%) Testing before treatment, estimate recovery probability, cull cows with low probability (<75%), don t cull high producing cows 7

8 Simulating subclincial and clinical IMI interventions 3 intervention strategies for clinical IMI Combined with intervention measures for subclinical IMI: Testing of cows after 2 high SCC, after 1 month cull still infected cows Cull bottom 25%, treat rest Treat top 25% for 5 days, treat rest for 3 days 8

9 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure But don t cull high producers Herd 1 (S. aureus) Basic3 187, CullBottom 200, TreatTopLonger 201, Before50 196, CullBottom 206, TreatTopLonger 205, notculltop 196, CullBottom 205, TreatTopLonger 204, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 9

10 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure But don t cull high producers Herd 1 (S. aureus) Basic3 187, CullBottom 200, TreatTopLonger 201, Before50 196, CullBottom 206, TreatTopLonger 205, notculltop 196, CullBottom 205, TreatTopLonger 204, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 10

11 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure But don t cull high producers Herd 1 (S. aureus) Basic3 187, CullBottom 200, TreatTopLonger 201, Before50 196, CullBottom 206, TreatTopLonger 205, notculltop 196, CullBottom 205, TreatTopLonger 204, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 11

12 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure Herd 2 (S. agalactiae) Basic3 155, CullBottom 200, TreatTopLonger 200, Before50 157, CullBottom 200, TreatTopLonger 200, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 12

13 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure Herd 2 (S. agalactiae) Basic3 155, CullBottom 200, TreatTopLonger 200, Before50 157, CullBottom 200, TreatTopLonger 200, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 13

14 Simulating subclinical and clinical IMI interventions Treatment: Strategy Gross income Clinical IMI Subclinical IMI Treatment days Culled cows 3 days Cull cows with low probability for cure Herd 2 (S. agalactiae) Basic3 155, CullBottom 200, TreatTopLonger 200, Before50 157, CullBottom 200, TreatTopLonger 200, CullBottom Cull bottom 25%, treat others TreatTopLonger Treat top 25% for 5 days instead of 3 14

15 Conclusion Intervention strategies for clinical and subclinical IMI can cost-effectively reduce IMI incidence. Strategy should be chosen herd-specific. This comes at the price of increased antibiotic usage or culling. High culling costs may lead to less cost-effective strategies. 15

16 Questions? Thank you for your attention. 16

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