Course Syllabus. Offered by School of Veterinary Medicine With effect from Semester A 2017 /18

Transcription

1 Offered by School of Veterinary Medicine With effect from Semester A 2017 /18 Part I Course Overview Course Title: Function and Dysfunction Course Code: VM 3100 Course Duration: 1 semester Credit Units: 18 credits Level: Proposed Area: (for GE courses only) Medium of Instruction: Medium of Assessment: Prerequisites: Precursors: Equivalent Courses: Exclusive Courses: B3 Arts and Humanities Study of Societies, Social and Business Organisations Science and Technology English English Completion of Year 2 courses with C grade or above Nil Nil Nil 2

2 Part II Course Details 1. Abstract The aim of this course is to develop the integration of the disciplines of physiology and pathology as pathophysiology including general and clinical pathology with histology, pharmacology, toxicology, and immunology. These disciplines provide a bridge between the basic sciences and clinical medicine. Students will gain a competent understanding of the integrated function and dysfunction of body system from the molecular/cellular level to the whole organism. It will also further develop an understanding of the basic mechanisms by which tissues and organisms react to insult and the basic mechanisms of the immune response. This course will provide the basis for further understanding of the pathogenesis and diagnosis of diseases that will be essential in future courses and in clinical rotations. Within this context, students will appreciate the fundamental basis of relevant diagnostic techniques and appropriate therapeutic strategies and consider a toxic event. The animal body comprises a large set of highly complex, but integrated, biological systems that operate over a wide range of levels, from the molecular to the whole animal. These systems provide mechanisms for gathering information from and interacting with both the external and internal environment, maintaining the stability of the internal environment and repairing structures and mechanisms that have suffered injury. This course will develop an understanding of how an animal maintains itself as a functional organism in the face of environmental challenges, diseases, functional structural disorders and injuries of all kinds. The course is concerned with understanding how body systems work, how veterinarians assess their function, what can go wrong with them, how they undergo repair and how veterinarians can aid the repair process. The various disciplines that contribute to this course are organised into the following sections: Pharmacology and Neurosciences, Cardiovascular and Blood, Renal, Respiratory, Gastrointestinal and Ruminant, Endocrine and Reproduction. While some course material lends itself more to a didactic delivery, the majority of the course will be addressed using a problem-based approach. 2. Course Intended Learning Outcomes (CILOs) (CILOs state what the student is expected to be able to do at the end of the course according to a given standard of performance.) No. CILOs # Weighting* (if applicable) 1. Describe the role of pathology and the pathologist in diagnostic medicine (RCVS). 2. List the basic tissue responses to injury and describe underlying mechanisms driving these responses (AVBC, RCVS). 3. Recognize and describe the features of abnormal tissue, determine what process or processes are occurring in the abnormal tissue, and formulate an appropriate morphologic diagnosis for the processes occurring in the abnormal tissue (AVBC, RCVS). 4. Develop a fundamental understanding of the animal s body systems as a whole, the "services" that each system provides and clinical signs are commonly associated with dysfunction of specific body systems (AVBC, RCVS). Discovery-enriched curriculum related learning outcomes (please tick where appropriate) A1 A2 A3 3

3 5. For each body system, explain the function of each organ and tissue, control mechanisms(s) that regulate its functions(s), factors (internal and external) that perturb the control mechanism, consequences of loss of control system, how is the function of the system is inter related to the function of other systems and how the system s organs handle both exogenous and endogenous compounds (AVBC, RCVS). 6. Understand the various cell types in each organ, their specialized structure and function within in the body systems, their organization (spatially and/or temporally) relative to other cells within the tissue or organ, and what functions the specialized cell confer on the organ (AVBC, RCVS). 7. Display comprehensive of tissue injury and repair. Focusing on the various ways in which a body system undergoes injury, lesions commonly encountered and aetiology and pathogenesis of each, how tissues in this organ respond to injury, how uninjured cells respond in the presence of injured cells, how the function of an organ is affected by injury to its cells, how are other systems affected by cellular injury in non-system organs, the clinical consequences of injury to this organs in a system, how cellular injury (organ dysfunction) in an organ is detected clinically and what the prognosis for organ or whole animal function given a specific injury to this system (AVBC, RCVS). 8. Explain what subcellular functions of the cells in a body system are subject to modulation by exogenous and endogenous factors (drugs, toxins, neurotransmitters, hormones, etc.), how is system function affected by modulation of subcellular functions and what factors enhance or impede the access of pharmacologic agents to the cells in this system (AVBC, RCVS). * If weighting is assigned to CILOs, they should add up to 100%. 100% 3. Teaching and Learning Activities (TLAs) (TLAs designed to facilitate students achievement of the CILOs.) TLA Brief Description CILO No. Hours/week (if applicable) Lectures 6 hrs/wk on lectures of body systems explaining the anatomy, pathology, pharmacology, and neuroscience elaborating concepts that the faculty knows are difficult for students. Introducing and expanding on topics that are not addressed by the small-group activities, but that are essential components of the veterinarian s database of. 4

4 Tutorial Cases Clinical Lectures Post Mortem Rounds Clinical Pathology Rounds Surgical Pathology Rounds on lectures of body systems explaining the anatomy, pathology, pharmacology, and neuroscience using a problem based approach. on cases lectures of specific diseases processes in body systems and explaining the anatomy, pathology, pharmacology, and neuroscience using a problem based approach. on post mortem cases, focusing on the patho diagnosis, clinical history and mechanism of disease. on daily clinical samples and their diagnosis focusing on endocrine test, clotting factors, RBC/WBC evaluation, fluid analysis, cytology, blood smears and urine analysis samples with discussion about the case, its diagnosis, clinical behaviour and role of veterinary diagnostic medicine. on daily clinical samples focusing on oncology and dermatopathology samples with discussion about the case, its diagnosis, clinical behaviour and the role veterinary diagnostic medicine. 6 hrs/wk 6 hrs/wk 1 hr/wk 1 hr/wk 1 hr/wk 4. Assessment Tasks/Activities (ATs) (ATs are designed to assess how well the students achieve the CILOs.) Assessment Tasks/Activities CILO No. Weighting Remarks * Continuous Assessment: 40% Individual Quizzes 36% Alternate weeks Tutorial Group Quizzes 4% Alternate weeks Examination: 60% (duration: 3 hours x 3) * The weightings should add up to 100%. 100% # Students must pass each examination and the continuous assessment as a whole to pass the course as a whole 5

5 5. Assessment Rubrics (Grading of student achievements is based on student performance in assessment tasks/activities with the following rubrics.) Assessment Task Criterion Excellent (A+, A, A-) 1. Individual Quizzes Ability to explain the anatomy, pathology, pharmacology, and neuroscience in various veterinary medical conditions 2. Group Quizzes Ability to explain the anatomy, pathology, pharmacology, and neuroscience in various veterinary medical conditions Excellent in Excellent in Good (B+, B, B-) Good in Good in Adequate (C+, C, C-) Basic competence in Basic competence in Marginal (D) Some deficiencies in Some deficiencies in Failure (F) Poor in Poor in 3. Examination Ability to explain the anatomy, pathology, pharmacology, and neuroscience in various veterinary medical conditions Excellent in and in Good in and in Basic competence in and in Some deficiencies in and in Poor in and in 6

6 Part III Other Information (more details can be provided separately in the teaching plan) 1. Keyword Syllabus (An indication of the key topics of the course.) Pharmacology, Neuroscience, Cardiovascular, Blood, Renal, Respiratory, Gastrointestinal, Ruminant, Endocrine, Reproduction, Anatomy, Autonomic Pharmacology, Anesthesia, Cardiopulmonary medicine, Cardiovascular Physiology, Clinical cardiology, Clinical Pathology, Clinical Urology and Endocrinology, Central Nervous System, Pharmacology, Gastrointestinal Physiology, General Inflammatory Mediators, Ion channels, Large Animal Medicine, Liver Physiology, Mast Cell Biology, Molecular Genetics, Neurology, Neuro Ovarian Physiology, Pain, Pharmacokinetics, Pathology, Renal Physiology, Reproductive Physiology, Respiratory Physiology, Ruminant Physiology, Small Animal Medicine, Smooth Muscle, Theriogenology, Introduction to Pathology, Lesion Description, Tissue Degeneration, Cellular Adaptation & Death, Hemodynamic Disorders, Shock, Immunology, Inflammation, Healing and Repair, Disturbances of Growth. 2. Reading List 2.1 Compulsory Readings (Compulsory readings can include books, book chapters, or journal/magazine articles. There are also collections of e-books, e-journals available from the CityU Library.) 1. Boron. W. F. and E. L. Boulpaep (2012). Medical Physiology: A Cellular and Molecular Approach. 2 nd ed. (updated). Philadelphia: Saunders. 2. Costanzo, L.S. (2014). Physiology,5 th ed. Philadelphia: Saunders. 3. Cunningham, J. G. and Klein, B. G. (2007). Textbook of Veterinary Physiology, 4 th ed. Philadelphia: W.B. Saunders.. 4 Pineda, M. H. and M. P. Dookey (2003). McDonald's Veterinary Endocrinology and Reproduction, 5th ed. Ames, IA: Iowa State Press. 5 Senger, P.L. (2012). Pathways to pregnancy and parturition 3 rd ed., Pullman, WA: Current Conceptions. 6 Ettinger, S. J. and Feldman, E. C. eds. (2010). Textbook of Veterinary Internal Medicine, 7 th ed. Philadelphia: W.B. Saunders. 7 Maxie, M.G., ed. (2016). Jubb, Kennedy, and Palmer's Pathology Of Domestic Animals, 6th ed. St. Louis, MO; Elsevier. 8 Kumar. V., A. K. Abbas. and J. C. Aster (2015). Robbins and Cotran Pathologic Basis of Disease, 9 th ed. Philadelphia: W.B. Saunders. 9 Stockham, S. L. and Scott, MA (2008). Fundamentals of Veterinary Clinical Pathology. 2 nd ed. Ames, IA Iowa State Press. 10 Latimer, K. S., ed. (2011). Duncan & Prasse's Veterinary Laboratory Medicine: Clinical Pathology, 5 th ed. Chichester, UK: Wiley-Blackwell. 11 Rang H, Ritter J, Flower R, Henderson G (2015). Rang & Dale's Pharmacology 8 th ed. London: Elsevier Churchill Livingstone. 12 Brunton, L. L., ed. (2011). Goodman & Gilman's The pharmacological basis of therapeutics, 12 th ed. New York: Mc Graw Hill. 13 Zachary JF, eds. (2016). Pathologic Basis of Veterinary Disease. 6th ed. St. Louis, MO: Elsevier; Elsevier Health Sciences. 14. Gupta R. (2012). Veterinary Toxicology: Basic and Clinical Principles 2 nd ed Elsevier. 2.2 Additional Readings (Additional references for students to learn to expand their about the subject.) 1. None