Deborah A. Cera - Division of Compliance Center for Veterinary Medicine, FDA
|
|
- Maximillian Maurice Lamb
- 5 years ago
- Views:
Transcription
1 Deborah A. Cera - Division of Compliance Center for Veterinary Medicine, FDA 1 1
2 Databases RVIS Interagency Database TRIMS An Interactive Database Containing Information Obtained During FDA/State Inspections of Firms Involved/Responsible for Tissue Residue Violations. Attachment C Ensures Consistent Data Collection by both Federal and State Investigators Attachment G Drug Inventory 2 2
3 Dairy Cow Tissue Residues DRUG Total Percent Amikacin % Ampicillin % Ceftiofur * * % Dihydrostreptomycin % Fenbendazole % Florfenicol % Flunixin % Furazolidone % Gentamicin % Kanamycin % Lincomycin % Neomycin % 3
4 DRUG Total Percent Oxytetracycline % Penicillin % Phenylbutazone % Sulfachlorpyridazine % Sulfadiazine % Sulfadimethoxine % Sulfamethazine % Sulfathiazole % Tetracycline % Tilmicosin % Tulathromycin % Tylosin % Total
5 Additional Background It is an FDA priority to ensure the safety of animal-derived foods for human consumption FDA works with USDA and the States to monitor meat, poultry, and milk for unapproved or unsafe drug and chemical residues Although only 7.7% of the cattle slaughtered in the United States are adult dairy cattle they represent 67% of the tissue residue violations 5
6 Poor Practices Leading to Tissue Residues Drug residue violations in dairy cattle often result from poor husbandry practices on the farm. These practices include: Failure to maintain treatment records Failure to identify treated animals Failure to follow labeled withdrawal times Increasing the labeled dosage Increasing the length of treatment Giving the drug by an unapproved route of administration Drug given in unapproved species 6
7 Importance of Following Label Directions FDA approved animal drugs are labeled with the approved species, dosage, route of administration, frequency of use, condition to be treated, and meat and milk withdrawal times. When the directions for use on the approved label are followed, drug residues in meat and milk should not exceed the established drug tolerance. Good management practices at dairy farms include maintaining records of each animal treated, what drug it was treated with, when it was treated, and how it was treated, for example the route of administration, dosage and duration of treatment. Such records can be used by producers to ensure that treated cows put back into the milking string or sold for slaughter have met appropriate drug withdrawal times in order to prevent illegal drug residues in milk and meat. 7
8 Federal/State Cooperative Program FDA and the States currently participate in the National Conference on Interstate Milk Shipments (NCIMS). NCIMS is a voluntary coalition of regulators established to ensure the safety and wholesomeness of fresh milk in the U.S. FDA publishes the Grade A Pasteurized Milk Ordinance (PMO) as a model ordinance for States to adopt. 8
9 Current Milk Testing Requirements The PMO currently requires the sampling and testing of milk from bulk milk pick-up tankers when the milk is received at dairy plants. This sampling consists of commingled raw milk collected from various dairy farms. The PMO only requires that bulk milk pickup tankers be tested for the presence of at least four of six specific Beta Lactam class drugs. 9
10 Additional Compound Classes of Concern There are many other classes of drugs used on farms that are not tested for on a routine basis such as sulfonamide antibiotics like sulfadimethoxine, aminoglycoside drugs such as gentamicin, and anti-inflammatory drugs like flunixin. USDA/FSIS tissue residue data for calendar years indicates that over 50% of the violative drug residues in edible tissues reported in culled dairy cows are from drugs other than beta-lactam class drugs. 10
11 FDA s Concern FDA is concerned that the same poor practices that lead to drug residues in tissues might also be leading to drug residues in milk, especially of non-beta lactam drugs. In November 2010 FDA announced that it had developed a milk sampling assignment to determine whether our concern has merit. 11
12 Feedback FDA received feedback from State regulators and milk industry associations that because of the on-farm sample collection approach, the proposed plan would have a negative impact on producers and would cause milk to be dumped. FDA then participated in three listening sessions to seek input on revising the plan in an effort to avoid disruption to the milk supply. 12
13 Revised Sampling Plan In response to input received at these Listening Sessions, informal face to face meetings, and many individual concerns of our stakeholders the Agency has completely revised its sample assignment strategy. 13
14 Samples to be Collected As required in the Pasteurized Milk Ordinance (PMO), when certified bulk milk hauler/samplers collect raw milk samples, the Universal Sampling System is employed, whereby samples are collected every time milk is picked up at the farm. It is these Universal Samples that will be collected during this sampling assignment. 14
15 Revised Sampling Plan cont. FDA Investigators will visit laboratories holding Universal Samples and collect 900 samples from farms that have had tissue residue violations and 900 cohort samples from dairy farms not known to have had previous tissue residue violations. 15
16 Revised Sampling Plan cont. The origin of all samples collected, whether from the targeted group of known tissue residue violators or the cohort sample group, will be blinded utilizing an independent third party, the Institute for Food Safety and Health (IFSH) in Summit Argo, IL. The milk samples from all farms will be analyzed by one of three FDA laboratories for a broad range of drugs to determine if the milk contains violative drug residues. 16
17 How Will Targeted Farms be Selected? The sampling assignment will include the violators that have had tissue residues with the highest risk scores in culled dairy cows. The Risk Model takes into account the hazard associated with the drug, the likelihood of exposure, and the exposure level. FDA Investigators will be given an alphabetical list of selected violators by state of origin. 17
18 Methods A fully validated multi-class, multi-residue liquid chromatography/tandem mass spectrometry screening and confirmation method will be used to identify violative drug residues in milk. Additionally ELISA technology will be used to detect the presence of several aminoglycoside class drugs. All residues of drugs with established tolerances will be quantitated to confirm the level of drug present. 18
19 DRUG SAFE/TOLERANCE LEVEL (ppb) Ampicillin (AMP) 10 Cephapirin (CEPH) 20 Cloxacillin (CLOX) 10 Penicillin G (PEN G) 5 Erythromycin (ERY) 50 Tylosin (TYL) 50 Ciprofloxacin (CIP) None a Sarafloxacin (SAR) None a Chlortetracycline (CTC) 300 b Oxytetracycline (OTC) 300 b Tetracycline (TC) 300 b Doxycycline (DC) None a Sulfachloropyridazine (SCP) 10 Sulfadiazine (SDZ) 10 Sulfamerazine (SMR) 10 Sulfadimethoxine (SDM) 10 a no tolerance set for milk; method target level set at 100 ppb for VIR and TIL and DC; 10 ppb for TUL; and 5 ppb for CIP, SAR, CAP and FF b Tolerance includes sum and individual residues; method target levels set at 100 ppb each, the sum of the tetracylines present should not exceed 300 ppb. c Amount listed is a safe level from 9/27/05 FDA/CFSAN Milk Safety Branch Memo 19
20 DRUG SAFE/TOLERANCE LEVEL (ppb) Sulfamethazine (SMZ) 10 Suflaquinoxaline (SQX) 10 Sulfathiazole (STZ) 10 Tripelennamine (TRIP) 20 Thiabendazole (THBZ) 50 Flunixin (FLU) (Flunixinhydroxide) 2 Bacitracin (BAC) 500 Virginiamycin (VIR) 100 Tilmicosin (TIL) 100 Florfenicol 0 Chloramphenicol 0 Tulathromycin 0 Gentamicin 30 Neomycin 150 a no tolerance set for milk; method target level set at 100 ppb for VIR and TIL and DC; 10 ppb for TUL; and 5 ppb for CIP, SAR, CAP and FF b Tolerance includes sum and individual residues; method target levels set at 100 ppb each, the sum of the tetracylines present should not exceed 300 ppb. c Amount listed is a safe level from 9/27/05 FDA/CFSAN Milk Safety Branch Memo 20
21 Samples to be Collected cont. The State Milk Regulatory Agency shall be advised of this assignment and laboratories involved prior to the collection of any samples. The State Milk Regulatory Agency will be invited to participate in any sampling conducted in their state. Such participation is totally at the discretion of the State. 21
22 Violative Samples No enforcement actions will be taken in response to violative levels of residues in these samples because the purpose of the assignment is to determine if a problem exists. 22
23 Findings FDA will use the resulting data to inform the ongoing Milk Drug Residue Risk Assessment. Depending on the findings, FDA in active consultation with the National Conference on Interstate Milk Shippers, may expand the requirements for milk testing under the PMO to include additional compounds. FDA may also revise Compliance Program to routinely require the testing of farm bulk milk tanks during the inspection of a farm due to a violative tissue residue. 23
24 Timeline Prior to implementing the Milk Sampling Assignment the Agency will hold teleconferences with the Commissioners, Secretaries, and Directors of State Departments of Agriculture, and State Milk Regulatory Officials. The Agency will also notify the Executive Board of the National Conference on Interstate Milk Shippers and other affected stakeholders, i.e., Industry, Consumer Groups, etc., prior to starting the assignment. There is no specific timeline but the assignment is expected to start within the next few months and will take approximately 12 months to complete. 24
25 In Conclusion FDA s Milk Sampling Assignment is targeting the few members of an otherwise compliant industry in order to ensure that the public can have the utmost confidence in the dairy products that they consume. FDA continues to believe that the nation s milk supply is safe. Efforts such as this sampling assignment will ensure that potential problems, if they exist, remain minor and are quickly mitigated by education and enforcement, as appropriate. 25
Milk and Dairy Beef Residues: Incidence & Communications. Dairy Response Planning Betsy Flores, Nat l Milk Producers Federation April 16, 2013
Milk and Dairy Beef Residues: Incidence & Communications Dairy Response Planning Betsy Flores, Nat l Milk Producers Federation April 16, 2013 What We ll Cover Antibiotics and milk production FDA drug residue
More informationFDA/CVM Div. of Compliance
Deborah A. Cera Division of Compliance Center for Veterinary Medicine, FDA This Compliance program contains Center instructions to Field investigators on how to conduct inspections to follow up violative
More informationResidues. Mike Apley, DVM, PhD
Residues Mike Apley, DVM, PhD Residues: It s Black and White Residues occur when detected concentrations of the marker residue are above the approved tolerance for that drug in that tissue. Residues are
More informationAvoiding residues and an FDA Inspection
Avoiding residues and an FDA Inspection James D. McKean, DVM, JD Extension Veterinarian Associate Director, Iowa Pork Industry Center Iowa State University x2mckean@iastate.edu USDA FSIS Residue Testing
More informationWhy? The dairy industry is now under increased drug residue surveillance. Meat and Milk Drug Residues: Current Dairy Industry Topics
Meat and Milk Drug Residues: Current Dairy Industry Topics The dairy industry is now under increased drug residue surveillance Why? Top Sources of Beef Carcass Drug Residues #1 Cull Dairy Cows #2 Veal
More informationVeterinary Feed Directive
Veterinary Feed Directive Medically Important Antibiotics in Animal Agriculture Outline Questions to Be Addressed What changes are being made and why? What drugs are affected, which ones are not? What
More informationMedically Important Antibiotics in Animal Agriculture
Medically Important Antibiotics in Animal Agriculture Craig Lewis, DVM MPH Office of the Director Center for Veterinary Medicine Farm Foundation Antimicrobial Stewardship Workshop Davis, California October,
More informationVeterinary Feed Directive Information
Veterinary Feed Directive Information Focus and Scope Veterinary- Patient-Client Relationship Veterinarian issuing a VFD is required to be licensed to practice veterinary medicine and operate in compliance
More informationVeterinary Feed Directive: What You Need to Know
Iowa Farm Bureau s Margin Management Webinar Series presents: Veterinary Feed Directive: What You Need to Know Are you prepared for implementation of the Veterinary Feed Directive on January 1, 2017? Introduction:
More informationThe VCPR and What Makes it Valid
The VCPR and What Makes it Valid Patrick J. Gorden, DVM, D-ABVP-Dairy Practice Veterinary Diagnostic and Production Animal Medicine Iowa State University College of Veterinary Medicine Introduction Antimicrobial
More informationCountry Report: Malaysia
Country Report: Malaysia Akma Ngah Hamid Director Central Region Veterinary Laboratory (CRVL) Dpt. of Veterinary Service Introduction Antimicrobials are essential drugs and used in human and veterinary
More informationOne Analysis, One Column, Less than 9 Minutes for Over 60 Multiclass Antibiotics
Featured Application: Multiclass Veterinary Antibiotics on Raptor C8 by LC- One Analysis, One Column, Less than 9 Minutes for Over 0 Multiclass Antibiotics Highly efficient peak separation and fast analysis
More informationShow Animals Challenges at the Packer. Paula Alexander Project Manager, Sustainable Food Production & Food Safety Quality Assurance
Show Animals Challenges at the Packer Paula Alexander Project Manager, Sustainable Food Production & Food Safety Quality Assurance 1 Show Animals Packer Challenges Residue Sampling Product on hold, tracking,
More informationRevolutionary Milk Analysis
Revolutionary Milk Analysis 2 Milk quality is a major concern Farmers, producers and laboratories have to meet European and international rules. They must perform even more stricter controls to ensure
More informationPreventing Sulfa Residues in Pork
1 of 7 4/29/2010 8:43 AM University of Missouri Extension G2358, Reviewed October 1993 Preventing Sulfa Residues in Pork John C. Rea Department of Animal Sciences Sulfa products and other antibiotics have
More informationChanges to Antibiotic Labeling & Veterinary Feed Directive. Craig A. Payne, DVM, MS Director, Veterinary Extension & CE University of Missouri
Changes to Antibiotic Labeling & Veterinary Feed Directive Craig A. Payne, DVM, MS Director, Veterinary Extension & CE University of Missouri Outline How did we get here? What changes will occur? Getting
More informationOutline Changes to Antibiotic Labeling & Veterinary Feed Directive
Outline Changes to Antibiotic Labeling & Veterinary Feed Directive Craig A. Payne, DVM, MS Director, Veterinary Extension & CE University of Missouri How did we get here? What changes will occur? Getting
More informationCurrent EU Antibiotic Maximum Residue Limits
R-Biopharm Rhône Current EU Antibiotic Maximum Residue Limits March 2011 R-Biopharm Rhône Current EU Antibiotic Limits 2 Contents Antibiotics in Food Aminoglycosides...4 Ansamycins...4 Beta-lactams...5
More informationChanges in Antibiotic Labeling Veterinary Feed Directive. Changes in Antibiotic Regulations. Concerns with Antibiotic Use 2/29/2016
Changes in Antibiotic Labeling Veterinary Feed Directive Craig A. Payne, DVM, MS Extension Veterinarian Commercial Agriculture Program University of Missouri Changes in Antibiotic Regulations How did we
More informationChanges in Antibiotic Labeling Veterinary Feed Directive
Changes in Antibiotic Labeling Veterinary Feed Directive Craig A. Payne, DVM, MS Extension Veterinarian Commercial Agriculture Program University of Missouri Changes in Antibiotic Regulations How did we
More informationAntibiotics use and Considerations: Calves and Heifers CLASSIFICATION OF CALVES. Danielle A. Mzyk TITLE 24 PT. ARIAL BOLD ALL CAPS
CALF AND HEIFER CONGRESS - 2016 Antibiotics use and Considerations: Calves and Heifers Danielle A. Mzyk TITLE 24 PT. ARIAL BOLD ALL CAPS Today s Presentation Classification of Calves Define Preruminant
More informationcrippling production of the bacterial cell wall that protects the cell from the external environment PS
Antibiotic Selection and Use in Cattle Dee Griffin DVM MS, Texas A&M Veterinary Medical Center, Canyon, TX 79016 Antibiotic use in food animals is increasingly scrutinized Much of the world s antibiotic
More informationDrug Use on the Farm & Antibiotic Resistance in Raw, Stored, & Treated Manures
Drug Use on the Farm & Antibiotic Resistance in Raw, Stored, & Treated Manures Jason Oliver, PhD Cornell PRO-DAIRY Dairy Environmental Systems Dairy Practices Council Annual Conference Buffalo, NY Nov.
More informationPremi Test. Art. No. R3900. R-Biopharm AG. Fast Determination of antibiotic residues in less than 4 hours
Premi Test Art. No. R3900 Fast Determination of antibiotic residues in less than 4 hours Easy Simple handling and no extraordinary cost intensive equipment needed Sensitive Detects antibiotic residues
More informationUSE OF ANTIBIOTIC RESIDUE TEST KITS FOR GOAT MILK. E. N. Escobar
USE OF ANTIBIOTIC RESIDUE TEST KITS FOR GOAT MILK E. N. Escobar E (Kika) de la Garza Institute for Goat Research Langston University Langston, Oklahoma 73050 Background and Purpose Mastitis is known as
More information11/22/2016. Veterinary Feed Directive. Medicated Feed Parentage. The Veterinarian and Medicated Feed: Roles. (Introduction) Type A medicated article
Medicated Feed Parentage Veterinary Feed Directive (Introduction) Drug(s) Feed Dragan Momcilovic DVM, PhD, DACT Veterinary Medical Officer Center for Veterinary Medicine (CVM) U.S. Food and Drug Administration
More informationThe Changing Veterinary Pharmaceutical Landscape
The Changing Veterinary Pharmaceutical Landscape Dan Grooms DVM, PhD Michigan State University College of Veterinary Medicine The use of pharmaceutical products in food animals is under close scrutiny
More informationHuman Food Safety of Veterinary Drugs. Bettye K. Walters, DVM
Human Food Safety of Veterinary Drugs Bettye K. Walters, DVM Bettye.walters@fda.hhs.gov Pertinent International Resources Organization for Economic Co-Operation and Development (OECD) Understanding the
More informationCOMPOUNDING REGULATORY PERSPECTIVE
COMPOUNDING REGULATORY PERSPECTIVE Janice Steinschneider Supervisory Regulatory Counsel Office of Surveillance & Compliance FDA/Center for Veterinary Medicine USP Veterinary Drugs Stakeholder Forum November
More informationBeef Producers. The Judicious Use of Antimicrobials for
The Judicious Use of Antimicrobials for Beef Producers Introduction The production of safe and wholesome animal products for human consumption is a primary goal of beef producers. To achieve that goal,
More informationVeterinary Feed Directives
VFD Where it is today Vita Plus Swine Summit Morton, MN March 30 th, 2016 Dr. J. Tyler Holck, DVM, MS, MBA Veterinary Feed Directives How did we get here? Impact Requirements Streamlining the Work Electronic
More informationMilk & Dairy Beef Drug Residue Prevention REFERENCE MANUAL 2018
TM Milk & Dairy Beef Drug Residue Prevention REFERENCE MANUAL 2018 TM National Milk Producers Federation (NMPF) does not endorse any of the veterinary drugs or tests identified on the lists in this manual.
More informationVFD Where it is today
VFD Where it is today Vita Plus Swine Summit Morton, MN March 30 th, 2016 Dr. J. Tyler Holck, DVM, MS, MBA Veterinary Feed Directives How did we get here? Impact Requirements Streamlining the Work Electronic
More informationDAIRY VETERINARY NEWSLETTER
DAIRY VETERINARY NEWSLETTER Drought Year Issues Include Aflatoxin Testing and Nitrate Testing of Feed Aflatoxins in corn and other feed crops during drought conditions September 2012 2012 is shaping up
More informationAgricultural Research Division, American Cyanamid Company, Princeton, NJ 08540
1 Antibiotics Use in Agriculture: An Overview Richard H. Gustafson Downloaded via 148.251.232.83 on October 16, 2018 at 00:12:00 (UTC). See https://pubs.acs.org/sharingguidelines for options on how to
More informationSurveillance for antimicrobial resistance in enteric bacteria in Australian pigs and chickens
Surveillance for antimicrobial resistance in enteric bacteria in Australian pigs and chickens Dr Pat Mitchell R & I Manager Production Stewardship APL CDC Conference, Melbourne June 2017 Dr Kylie Hewson
More informationTable 1. Adequacy of Recommended Milk Discard Times (Seymour et al., 1988)
publication 404-401 On-farm Tests for Drug Residues in Milk G. M. Jones, Professor and Extension Dairy Scientist, Milk Quality & Milking Management, Department of Dairy Science, Virginia Tech Introduction
More informationPART 530 EXTRALABEL DRUG USE IN ANIMALS
529.2503 (c) Conditions of use (1) Amount. 6 grams per day, intrauterine, for 3 consecutive days during estrus. (2) Indications for use. Horses. Intrauterine treatment of endometritis caused by beta-hemolytic
More informationProject Summary. Impact of Feeding Neomycin on the Emergence of Antibiotic Resistance in E. coli O157:H7 and Commensal Organisms
Project Summary Impact of Feeding Neomycin on the Emergence of Antibiotic Resistance in E. coli O157:H7 and Commensal Organisms Principal Investigators: Mindy Brashears, Ph.D., Texas Tech University Guy
More informationMitigating Pain in Livestock: What Options are Available
Mitigating Pain in Livestock: What Options are Available NIAA 2014 Annual Conference Omaha, Nebraska April 2, 2014 Craig A. Lewis, DVM, MPH, DACVPM Center for Veterinary Medicine U.S. Food and Drug Administration,
More informationAntimicrobial Use & Antimicrobial Resistance
Your health and safety our priority. Votre santé et votre sécurité notre priorité. Helping the people of Canada maintain and improve their health Aider les Canadiens et les Canadiennes à améliorer leur
More informationThe Future of Antibiotic Alternatives
The Future of Antibiotic Alternatives @Elanco #feedthe9 Grady Bishop Sr. Director Market Access Elanco 1 The Global Landscape our WHY 2 Today s 3 Food Security Realities 3 The Protein Gap 4 The impact
More informationThe public health implications of antibiotic use in dairy cattle and management strategies to ensure their judicious use
VIRGINIA POLYTECHNIC AND STATE UNIVERSITY The public health implications of antibiotic use in dairy cattle and management strategies to ensure their judicious use Katharina Russ 4/28/2011 Introduction:
More informationAmerican Veterinary Medical Association
A V M A American Veterinary Medical Association 1931 N. Meacham Rd. Suite 100 Schaumburg, IL 60173-4360 phone 847.925.8070 800.248.2862 fax 847.925.1329 www.avma.org March 31, 2010 Centers for Disease
More informationMonitoring of Antibiotic Residues in Milk Development of the New Biosensor System MCR 3 for Routine Practical Analyses
Milchprüfring Bayern e.v. Monitoring of Antibiotic Residues in Milk Development of the New Biosensor System MCR 3 for Routine Practical Analyses Innovation Networking Transparency Information Milchprüfring
More informationMethods development to detect antibiotic activity in water samples
Methods development to detect antibiotic activity in water samples Stefan Kools (Grontmij AquaSense) Marta Wilgosz (Grontmij AquaSense, WUR) Evertjan van de Brandhof (RIVM) Gerard Stroomberg (Waterdienst)
More informationCALIFORNIA EGG LAWS & REGULATIONS: BACKGROUND INFORMATION
CALIFORNIA EGG LAWS & REGULATIONS: BACKGROUND INFORMATION On November 4, 2008, California voters passed Proposition 2, which changes the way many hens in egg production are housed today. California passed
More informationEurEau s Contribution to the European Commission s Strategic Approach on Veterinary Pharmaceuticals in the Environment
EurEau s Contribution to the European Commission s Strategic Approach on Veterinary Pharmaceuticals in the Environment Summary Globally, pharmaceutical products are regularly administered to both livestock
More informationRegulatory Services News
Regulatory Services News Vol. 58, No.4 Feed - Fertilizer - Milk - Seed - Seed Testing - Soil Winter 2015 Director s Digest- Fourth Quarter 2015 Those who are ill informed about change will be at risk for
More informationTHIS ARTICLE IS SPONSORED BY THE MINNESOTA DAIRY HEALTH CONFERENCE.
THIS ARTICLE IS SPONSORED BY THE MINNESOTA DAIRY HEALTH CONFERENCE. ST. PAUL, MINNESOTA UNITED STATES OF MINNESOTA -59- Antibiotic Residues: Perception vs. Reality Gary D. Neubauer D.V.M. Pharmacia & Upjohn
More informationDETECTION OF INHIBITORY SUBSTANCES IN MILK
DETECTION OF INHIBITORY SUBSTANCES IN MILK DELVOTEST P 5 PACK/Visual & DelvoScan Reader (raw commingled cow milk, raw commingled goat milk and NCIMS accepted pasteurized cow and goat milk products) [Unless
More informationUse of antibiotics in livestock production in light of new FDA guidelines Chris Rademacher, DVM
Use of antibiotics in livestock production in light of new FDA guidelines Chris Rademacher, DVM ISU Swine Extension Veterinarian Agenda Definitions FDA Guidance 209/213 regulations VFD Regulations Summary
More informationResult of the OIE data collection
Delfy Góchez Chargée de mission Result of the OIE data collection Lessons learned and expectations Beirut, November 8th 2017 Reporting Options The sections of the OIE Template named Reporting Options 1,
More informationRESIDUE MONITORING AND CONTROL PROGRAM. Dr. T. Bergh Acting Director: Veterinary Public Health Department Agriculture, Forestry and Fisheries
RESIDUE MONITORING AND CONTROL PROGRAM Dr. T. Bergh Acting Director: Veterinary Public Health Department Agriculture, Forestry and Fisheries Scope of Presentation Introduction Roles Residue control programmes
More informationBeef Quality Assurance Program
Bovine Pharmacology Beef Quality Assurance Program Purpose Supply only quality beef Improve consumer perception of beef s safety Elimination of drug residues Elimination of edible tissue blemishes and
More informationAquaculture Drugs: Industry Concerns
Washington DC New York Denver Seattle Aquaculture Drugs: Industry Concerns Lisa Weddig Vice President, Regulatory and Technical Affairs National Fisheries Institute Who is NFI? Leading advocacy organization
More informationTHE FARAD NEWSLETTER US FARAD
1-888-US FARAD THE FARAD NEWSLETTER An electronic publication from the Food Animal Residue Avoidance Databank (FARAD) for veterinarians, animal scientists, extension specialists and the regulatory community.
More informationPerformance Information. Vet use only
Performance Information Vet use only Performance of plates read manually was measured in three sites. Each centre tested Enterobacteriaceae, streptococci, staphylococci and pseudomonas-like organisms.
More informationValidation of the Charm 3 SL3 -Lactam Test for Screening Raw Milk in Compliance with the U.S. Pasteurized Milk Ordinance
348 SALTER ET AL.: JOURNAL OF AOAC INTERNATIONAL VOL. 94, NO. 1, 2011 VETERINARY DRUG RESIDUES Validation of the Charm 3 SL3 -Lactam Test for Screening Raw Milk in Compliance with the U.S. Pasteurized
More informationThe development of a new multiplex dipstick for the simultaneous detection of sulfonamides, (fluoro)quinolones, tylosin and chloramphenicol in honey
The development of a new multiplex dipstick for the simultaneous detection of sulfonamides, (fluoro)quinolones, tylosin and chloramphenicol in honey Stefan Weigel (RIKILT), Vincent Chabottaux (Unisensor)
More informationResponsible Use of Veterinary Products. Bettye K. Walters, DVM
Responsible Use of Veterinary Products Bettye K. Walters, DVM Bettye.walters@fda.hhs.gov Pertinent International Resources Organization for Economic Co-Operation and Development (OECD) Understanding the
More informationUsing Antimicrobials Like We Want to Keep Them. Mike Apley, DVM, PhD Kansas State University
Using Antimicrobials Like We Want to Keep Them Mike Apley, DVM, PhD Kansas State University Therapy Prevention Control Regluations Animal Medicinal Drug Use Clarification Act (AMDUCA) Regulations published
More informationa commitment to milk quality
a commitment to milk quality Antibiotic use and its role in ensuring safe, wholesome milk Did you know? Dairy cows are under regular care of licensed veterinarians. Sick animals may need medication to
More informationMixtures of veterinary medicinal compounds in manured soils
Workshop Pharmaceuticals in Soil, Sludge and Slurry Mixtures of veterinary medicinal compounds in manured soils Nadine Tauchnitz Daniela Gildemeister, Silvia Berkner Dessau-Roßlau, 18th June to 19th June
More informationCLINICAL MASTITIS PERCEPTIONS OF KANSAS DAIRY PRODUCERS. J.R. Roberson 1
Dairy Day 2003 CLINICAL MASTITIS PERCEPTIONS OF KANSAS DAIRY PRODUCERS J.R. Roberson 1 Summary Mastitis is considered the most costly disease in the U.S. dairy industry. Treatment of clinical mastitis
More informationDetermination, Confirmation and Quantitation of Multi-Class Antibiotic Residues in Milk by UHPLC MS/MS
APPLICATION NOTE Liquid Chromatography/ Mass Spectrometry Authors: Avinash Dalmia PerkinElmer, Inc. Shelton, CT Determination, Confirmation and Quantitation of Multi-Class Antibiotic Residues in Milk by
More informationAn LC-MS/MS method to determine antibiotic residues in distillers grains
An LC-MS/MS method to determine antibiotic residues in distillers grains Hemakanthi de Alwis FDA Center for Veterinary Medicine Office of Research 07-31-2018 Distillers grain (DG) q DG is a major co-product
More informationThe use of antimicrobials in livestock production and antimicrobial resistance in pathogens from livestock
The use of antimicrobials in livestock production and antimicrobial resistance in pathogens from livestock Dr. W K de Silva Director General Department of Animal Production and Health Production 2011 Milk
More informationGlobal Overview on Antibiotic Use Policies in Veterinary Medicine
Global Overview on Antibiotic Use Policies in Veterinary Medicine Dr Shabbir Simjee Global Regulatory & Technical Advisor Microbiology & Antimicrobials Elanco Animal Health Basingstoke, England simjeess@elanco.com
More informationAnalysis of Multiclass Veterinary Drugs in Baby Food by Ultra Fast Chromatography with High Performance Triple Quadrupole Mass Spectrometry
Analysis of Multiclass Veterinary Drugs in Baby Food by Ultra Fast Chromatography with High Performance Triple Quadrupole Mass Spectrometry Charles Yang, 1 Dipankar Ghosh, 1 Mary Blackburn, 1 Jamie Humphries
More informationFACT SHEETS. On the Danish restrictions of non-therapeutical use of antibiotics for growth promotion and its consequences
12 July 2010 FACT SHEETS On the Danish restrictions of non-therapeutical use of antibiotics for growth promotion and its consequences Denmark is a major livestock producer in Europe, and the worlds largest
More information[amended May 5, 2005]
The FARAD Newsletter is an electronic publication from the Food Animal Residue Avoidance Databank (FARAD) for veterinarians, animal scientists, extension specialists and the regulatory community. Issue
More informationALDI US. Animal Welfare. Buying Policy Date: 05/
ALDI US Animal Welfare Buying Policy Date: 05/2018 www.aldi.us Animal Welfare Policy Statement As a leading grocery retailer, ALDI US is committed to the well-being of the animals in our supply chain.
More informationManureTracker: On the Trail of Hormones, Antimicrobials and Antimicrobial Resistance Genes
ManureTracker: On the Trail of Hormones, Antimicrobials and Antimicrobial Resistance Genes Francis J. Larney 1, Srinivas Sura 2, Shanwei Xu 1, Edward Topp 2, and Tim A. McAllister 1 1 Agriculture & Agri-Food
More informationUnderstanding the Veterinary Feed Directive
Understanding the Veterinary Feed Directive JENNIFER R. KAUF, VMD D A I R Y S I D E V E T E R I N A R Y S E R V I C E M A R T I N S B U R G, P A J U N E 2 9-3 0, 2 0 1 6 One Health Integrative effort of
More informationPET FOOD REGULATIONS & INGREDIENT DEFINITIONS FOR CONSUMERS
This document is based on the Model Bills and legal definitions published in the AAFCO Official Publication. All content is accurate and written in consumer language (not legal language). This document
More informationResidue Avoidance. Allyson Tjoelker Houston Livestock Show & Rodeo
Residue Avoidance Allyson Tjoelker Houston Livestock Show & Rodeo Why do we test? Protect the safety of the food supply Foster fair competition HLSR Drug Rules Unapproved Drug Use: The showing of any animal
More informationAntibiotic Residues in Meat and Meat Products, Implications on Human Health
Antibiotic Residues in Meat and Meat Products, Implications on Human Health Loinda Rugay Baldrias, DVM, MVS, PhD Dean, Professor College of Veterinary Medicine University of the Philippines Los Banos National
More informationAntibiotics in Honey. Centre for Science and Environment
Antibiotics in Honey (CSE Study) We are here because Antibiotics in our food are now a global health concern: Adverse health impacts Proliferating resistance in bacteria, thereby making antibacterial treatment
More informationAMU/AMR Policy for animals in Korea Jaehong CHANG, DVM, MS
AMU/AMR Policy for animals in Korea Jaehong CHANG, DVM, MS Deputy Director of Animal Health Management Division, Ministry of Agriculture, Food and Rural Affairs, Republic of Korea Contents Background Consequence
More informationUse of Antibiotics. In Food-Producing Animals: Facilitated Discussions with Ontario Veterinarians Involved with. Food-Producing Animal Practice
Use of Antibiotics In Food-Producing Animals: Facilitated Discussions with Ontario Veterinarians Involved with Food-Producing Animal Practice February April 2015 A Component of the College of Veterinarians
More informationJUNIOR DIVISION Market Lambs
New Mexico State Fair September 6 16, 2018 JUNIOR DIVISION Market Lambs Division 29 Superintendent Patrick Sullivan, Ph.D. Judge Steve Sturtz Classifier Jo Cook Check In: Arrive by 5:00 pm, Sunday, September
More informationUnapproved Animal Drugs Initiative
Animal Drugs Initiative Elizabeth Luddy, DVM Deputy Director Office of New Animal Drug Evaluation Center for Veterinary Medicine Animal Drugs Initiative Publically launched December 20, 2010 drugs webpage
More informationSome Thoughts about Antibiotic Stewardship and Choices of Antibiotic Use in Beef Cattle. Syracuse, NY January 22-23, 2016
Some Thoughts about Antibiotic Stewardship and Choices of Antibiotic Use in Beef Cattle Syracuse, NY January 22-23, 2016 R. L. Rick Sibbel DVM Director, US Cattle Technical Services Merck Animal Health
More informationThe VFDs Are Coming!
The VFDs Are Coming! January 1, 2017 Are You Ready? Federal Regulatory Bodies 1 Growing concern over antimicrobial resistance 2 Veterinary Feed Directive (VFD) President Clinton signed the Animal Drug
More informationQuality Services International GmbH. Testreport. Czech Honey Prokes Blanka M. Lukes Hajni 1363 CZ Prague Czech Republic
QSI GmbH - D- Czech Honey Prokes Blanka M. Lukes Hajni 1363 CZ-19800 Prague Czech Republic Order No.: 695699/12679 Date: 20-Dec-2016 Product: Honig/Honey Kind: Label: ohne/without Testreport Sample No:
More informationTexas Cattle Trichomoniasis Program Adopted: Interstate Rules Effective April 1, 2009; In-State Rules Effective Jan. 1, 2010
Texas Cattle Trichomoniasis Program Adopted: Interstate Rules Effective April 1, 2009; In-State Rules Effective Jan. 1, 2010 Beginning April 1, 2009, breeding bulls entering Texas from any other state
More informationCRISPR Diversity and Antimicrobial Susceptibility of Salmonella Isolates from Dairy Farm Environments in Texas
CRISPR Diversity and Antimicrobial Susceptibility of Salmonella Isolates from Dairy Farm Environments in Texas Principal Investigators: Kevin Cummings, Tom Edrington, Guy Loneragan Texas A&M University;
More informationMedically Important Antimicrobials in Animal Agriculture. Sheep
Medically Important Antimicrobials in Animal Agriculture Sheep Mike Murphy DVM, JD, Ph.D., DABVT, DABT Veterinary Medical Officer Office of the Director Center for Veterinary Medicine FDA Outline Take
More informationJUNIOR DIVISION. Replacement Dairy Heifers
New Mexico State Fair September 7 17, 2017 JUNIOR DIVISION Replacement Dairy Heifers Division 33 Superintendent Sharla Sharp Judge TBA Check In Arrive by 5:00 pm, Tuesday, September 12, 2017 **Check In
More informationRESPONSIBLE ANTIMICROBIAL USE
RESPONSIBLE ANTIMICROBIAL USE IN THE CANADIAN CHICKEN AND TURKEY SECTORS VERSION 2.0 brought to you by: ANIMAL NUTRITION ASSOCIATION OF CANADA CANADIAN HATCHERY FEDERATION CANADIAN HATCHING EGG PRODUCERS
More informationCenter for Veterinary
Center for Veterinary Medicine: Overview Sanja Modric, DVM, PhD Office of New Animal Drug Evaluation Center for Veterinary Medicine i Food and Drug Administration USP Veterinary Stakeholder Forum, 11-09-2012
More informationManagement to Prevent Drug Residue Problems in Pork
NUTRITION Extension Bulletin E-1749, October 1983 COOPERATIVE EXTENSION SERVICE MICHIGAN STATE UNIVERSITY Management to Prevent Drug Residue Problems in Pork Authors: Gary L. Cromwell, University of Kentucky
More informationAMR Industry Alliance Antibiotic Discharge Targets
AMR Industry Alliance Antibiotic Discharge Targets List of Predicted No-Effect Concentrations (PNECs) The members of the AMR Industry Alliance have developed a unified approach to establishing discharge
More informationManagement Issues That You Need To Know About. Dr. Matt Hersom Extension Beef Cattle Specialist Dept. of Animal Sciences
Management Issues That You Need To Know About Dr. Matt Hersom Extension Beef Cattle Specialist Dept. of Animal Sciences Topics of Concern Veterinary Feed Directive Food Safety and Modernization Act Veterinary
More informationPipestone Veterinary Services
NIAA: 2017 Antibiotic Symposium Oct 31 Nov 2, 2017 Joel Nerem, DVM Pipestone Veterinary Services 5 Locations Pipestone, MN Independence, IA Ottumwa, IA DeKalb, IL Rensselaer, IN Mixed Animal Practice.
More informationUsing Charm II 7600 For Residue Testing in Meats in Barbados
Using Charm II 7600 For Residue Testing in Meats in Barbados Dr Trevor King/ June Roach, Vet Services Lab (VSL) Ministry of Agriculture & Rural Development, Barbados VSL s Client Base Poultry In dustry
More informationAnalysis of Hormones & Anabolics
Analysis of Hormones & Anabolics Hormones and anabolics can be used as growth promoters in livestock breeding to enhance average daily weight gain and meat/fat ratio. As a consequence, hormone and anabolic
More information328 A Russell Senate Office Building United States Senate
July 3, 2012 The Honorable Debbie Stabenow The Honorable Herb Kohl Chair Chair Committee on Agriculture Subcommittee on Agriculture Committee on Appropriations 328 A Russell Senate Office Building S-128
More informationFact Sheet: Veterinary Natural Health Products and CQM
January 2008 Fact Sheet: Veterinary Natural Health Products and CQM Introduction: The demand for organic production is increasing across Canada and the number of organic dairy farms is increasing to meet
More information