DNA tests. for dogs/cats. DNA based testing for inherited diseases. Genetic identification of dogs and cats

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1 DNA tests for dogs/cats July 2014 DNA based testing for inherited diseases Genetic identification of dogs and cats The DNA certified parentage The dog/cat DNA test expert

2 ANTAGENE products Prices (tax included) and terms of sales valid until December 31st 2014 The genetic identification of stud dogs and stud cats DNA certify the identity of your stud dogs /cats Get a unique ID card of your dogs /cats Enhance your stud dogs / cats Reassure the breeders who are requesting your stud dogs / cats ISAG2006 / ISAGF2012 DNA Profile performed in 7 days DNA certified parentage of puppies and kittens DNA certify the genealogy of your puppy / kitten Promote your selection work Present the parentage certificate of your puppies / kittens, a trustmark for your customers Identify puppies and kittens from a double mating Parentage verification Request a parentage certificate for your kittens and puppies already geneticaly identified OPTIGEN Tests Prices and terms available on antagene.com/en Screening of the prcd form of the (PRA-prcd) and of the Colley Eye Anomaly (CEA) Prices valid until December 31st (0)

3 The screening of dogs and cats inherited diseases Protect your kennel/cattery Your kennel/cattery is free from an inherited disease Do not let enter Select clear breeding animal, not carrying the disease Do not introduce affected or carrier breeding animals in your kennel / cattery Produce clear puppy/ kitten, not carrying the disease Avoid producing puppies/kittens affected from an inherited disease You have breeding animals carriers in your kennel Do not let the disease spread into your kennel/cattery Select your clear or carrier breeding dog/ cat Adapt matings Produce puppy/kitten who will not develop the disease

4 A B C Featured Dog DNA tests Altdeutsche Schäferhunde American Cocker Spaniel American Staffordshire Terrier NCL-A Cerebellar Ataxia Australian Cattle Dog Australian Shepherd CEA/CH* Collie Eye Anomaly / Choroidal Hypoplasia HSF4-A Hereditary Cataract Barzoï Beagle MLS Musladin-Lueke Syndrome Bernese Mountain Dog Border Collie CEA/CH* Collie Eye Anomaly / Choroidal Hypoplasia Boston Terrier EHC Early-Onset Hereditary Cataract Boxer Briard CNB Congenital Stationary Night Blindness Bulldog Bullmastiff APR-rho CMR1 Multifocal Retinopathy Cavalier King Charles Spaniel CKCSID Congenital Keratoconjunctivitis Sicca EFS Episodic Falling Syndrome Chinese Crested Dog Colley CEA/CH* Collie Eye Anomaly / Choroidal Hypoplasia Continental Toy Spaniel Papillon Coton de Tulear BNAT Ataxie Néonatale (Bandera s Neonatal Ataxia) CMR2 Multifocal Retinopathy Czechoslovakian Wolfdog NAH Pituitary Dwarfism D E F G H I J K Dachshund OI Osteogenesis Imperfecta Dobermann English Cocker Spaniel FN Familial Nephropathy English Mastiff APR-rho CMR1 Multifocal Retinopathy English Pointer AMS Acral Mutilation Syndrome English Setter APR-rcd4 NCL-D Neuronal Ceroid Lipofuscinosis English Springer Spaniel AMS Acral Mutilation Syndrome Entlebucher Mountain Dog, Finnish Lapphund French Mastiff CMR1 Multifocal Retinopathy HFH-B Hereditary Footpad Hyperkeratosis French Spaniel AMS Acral Mutilation Syndrome German Shepherd Dog NAH Pituitary Dwarfism German Short-haired Pointer AMS Acral Mutilation Syndrome CD Cone Degeneration Golden Retriever ICT-A Ichthyosis Great Pyrenees CMR1 Multifocal Retinopathy Hovawart Irish Setter APR-rcd1 CLAD Canine Leukocyte Adhesion Deficiency APR-rcd4 Irish Terrier HFH-A Hereditary Footpad Hyperkeratosis Jack Russell Terrier Jagdterrier Kerry Blue Terrier Kromfohrländer HFH-A Hereditary Footpad Hyperkeratosis Kuvasz

5 L M N O P R S Labrador Retriever CNM Centronuclear Myopathy Lancashire Heeler Landseer CYST Cystinuria Large Munster Spaniel Lapponian Herder Long Hair Whippet Manchester Terrier Miniature Bull Terrier Newfoundland CYST Cystinuria Nova Scotia Duck Tolling Retriever Old English Sheepdog PCD Primary Ciliary Dyskinesia Parson Russell Terrier Patterdale Terrier Pinscher Poodle Portuguese Water Dog Pug Rhodesian Ridgeback Riesenschnauzer Russian Black Terrier Saarloos Wolfdog NAH Pituitary Dwarfism Samoyed APR-rpgr Schipperke Scottish Terrier VWD3 Von Willebrand s Disease Type 3 Sealyham Terrier Setter Gordon APR-rcd4 NCL-D Neuronal Ceroid Lipofuscinosis T V W Z Shetland Sheepdog CEA/CH* Collie Eye Anomaly / Choroidal Hypoplasia Siberian Husky APR-rpgr Sloughi APR-pde6b Staffordshire Bull Terrier HC Hereditary Cataract L2HGA Aciduria L-2-Hydroxyglutaric Swedish Lapphund Tibetan Terrier Volpino Italiano Weimaraner Welsh Corgi Cardigan APR-rcd3 Welsh Corgi Pembroke Welsh Terrier White Swiss Shepherd Wire-haired Fox Terrier Zwergspitz See full descriptions of diseases and DNA tests * PRA-prcd and CEA tests are performed by OPTIGEN and are not part of antagene SELECTION. Please contact us to get their updated prices

6 List of dog DNA tests AMS Acral Mutilation Syndrome French Spaniel, German Short-haired Pointer, English Pointer, English Springer Spaniel BNAT Neonatal Ataxia (Bandera s Neonatal Ataxia) Coton de Tulear CD Cone Degeneration German Shorthaired Pointer CEA/CH Collie Eye Anomaly / Choroidal Hypoplasia Rough Collie, Smooth Collie, Australian Shepherd, Shetland Sheepdog, Border Collie CKCSID Congenital Keratoconjunctivitis Sicca and Ichtyosiform Dermatosis Cavalier King Charles CLAD Canine Leukocyte Adhesion Deficiency Irish Setter CMR1 Multifocal Retinopathy Great Pyrenees, English Mastiff, Bullmastiff, French Mastiff CMR2 Multifocal Retinopathy Coton de Tulear CNB Congenital Stationary Night Blindness Briard CNM Centronuclear Myopathy Labrador Retriever COUL Coat Colour Newfoundland, Tibetan Terrier, Shar-Peï, Labrador Retriever, Flat Coated Retriever, Poodle, Dalmatian, French Spaniel CYST Cystinuria Newfoundland, Landseer DIL Dilution Great Dane, Dobermann, Shar-Peï, Azawakh, Greyhound, Whippet, Belgian Shepherd, American Staffordshire Terrier, Staffordshire Bull Terrier, Ratier de Prague Borzoi, Boxer, Chesapeake Bay Retriever, Great Pyrenees, Welsh Corgi Pembroke, Pug, Shetland Sheepdog, Poodle, Soft-Coated Wheaten Terrier, Kerry Blue Terrier, Saarlooswolfhond, White Swiss Shepherd, Altdeutsche Schäferhunde, Bernese Mountain Dog, German Shepherd Dog, Rhodesian Ridgeback, Hovawart, Czechoslovakian Wolfdog, Rough Collie, Smooth Collie, Cardigan Welsh Corgi EFS Episodic Falling Syndrome Cavalier King Charles Spaniel EHC Early-Onset Hereditary Cataract Boston Terrier FN Familial Nephropathy English Cocker Spaniel HC Hereditary Cataract Staffordshire Bull Terrier HFH-A Hereditary Footpad Hyperkeratosis Irish Terrier, Kromfohrländer HFH-B Hereditary Footpad Hyperkeratosis French Mastiff HSF4-A Hereditary Cataract Australian Shepherd Australian Shepherd, American Staffordshire Terrier, Grand Müsterländer, Giant Schnauzer, Pomeranian, German Sheperd, Parson Russell Terrier, Jack Russell Terrier, Bulldog, Weimaraner, Black Russian Terrier ICT-A Ichthyosis Golden Retriever L2HGA L-2-Hydroxyglutaric Aciduria Staffordshire Bull Terrier Rough Collie, Smooth Collie, Shetland Sheepdog, Border Collie, Australian Shepherd, White Swiss Shepherd, German Shepherd, Long-haired Whippet, Australian Cattle Dog, Old English Sheepdog MLS Musladin-Lueke Syndrome Beagle NAH Pituitary Dwarfism German Shepherd Dog, Czechoslovakian Wolfdog, Saarloos Wolfdog NCL-A Cerebellar Ataxia American Staffordshire Terrier, American Bully, Pit Bull Terrier NCL-D Neuronal Ceroid Lipofuscinosis English Setter, Gordon Setter OI Osteogenesis Imperfecta Dachshund PCD Primary Ciliary Dyskinesia Old English Sheepdog PL Hair Length Hungarian Pointing Dog (Vizsla), Alaskan Malamute, Welsh Corgi Cardigan, Welsh Corgi Pembroke, German Shepherd Dog, Altdeutsche Schäferhunde, Belgian Shepherd, Dutch Shepherd Dog, Mastiff, Schipperke, Weimaramer, White Swiss Shepherd Miniature Bull Terrier, Chinese Crested Dog, Jagd Terrier, Jack Russell Terrier, Parson Russell Terrier, Tibetan Terrier, Wire-haired Fox Terrier, Welsh Terrier, Lancashire Heeler, Patterdale Terrier, Sealyham Terrier, Australian Cattle Dog, Volpino Italiano PRA-pde6b Sloughi PRA-prcd English Cocker Spaniel, Labrador Retriever, Poodle (miniature, toy, dwarf), American Cocker Spaniel, Australian Cattle Dog, Chesapeake Bay Retriever, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, American Eskimo Dog, Chinese Crested Dog, Entlebucher Mountain Dog, Finnish Lapphund, Kuvasz, Lapponian Herder, Swedish Lapphund, Giant Schnauzer, Schipperke PRA-rcd1 Irish Setter PRA-rcd3 Cardigan Welsh Corgi PRA-rcd4 Irish Setter, Gordon Setter, English Setter PRA-rho English Mastiff, Bullmastiff PRA-rpgr Siberian Husky, Samoyed QC Short Tail Australian Shepherd, Pyrenean Mountain Dog, Australian Stumpy Tail Cattle Dog, Bourbonnais Pointing Dog, Brittany Spaniel, Jack Russell Terrier, Croatian Sheepdog, Savoie Shepherd Dog, Polish Lowland Sheepdog, Spanish Water Dog, Karelian Bear Dog, Mudi, Austrian Pinscher, Schipperke, Brasilian Terrier, Swedish Vallhund, Catahoula, Welsh Corgi Pembroke VWD1 von Willebrand's Disease Type I Doberman Pinscher, Poodle, Bernese Mountain Dog, Manchester Terrier, Kerry Blue Terrier, Pinscher, Continental Toy Spaniel Papillon, Coton de Tulear, Pembroke Welsh Corgi VWD3 von Willebrand's Disease Type III Scottish Terrier

7 Cat DNA tests A B C E H M HCM-A SMA Abyssinian American Curl American Wirehair Balinese Bengal Birman British Longhair British Shorthair Burmilla Chartreux Cornish Rex Exotic Shorthair Hypertrophic Cardiomyopathy Spinal Muscular Atrophy Highland Fold Maine Coon N O P R S T GSD4 HCM-C Munchkin Norwegian Forest Cat Glycogen Storage Disease Type IV Hypertrophic Cardiomyopathy Ocicat Oriental Persian Peterbald Ragdoll Scottish Fold Selkirk Rex Siamese Singapura Somali Tonkinese Thai AMB Amber Norwegian Forest Cat CP Colour Point All cat breeds (not necessary for Birman, Siamese, Ragdoll...) ERYN Neonatal Isoerythrolysis All cat breeds except Ragdoll, Sphynx, Turkish Angora, wild cats and hybrids (Bengal, Savannah, Chausie ) GSD4 Glycogen Storage Disease type IV Norwegian Forest Cat HCM-A Hypertrophic Cardiomyopathy Maine Coon HCM-C Hypertrophic Cardiomyopathy Ragdoll Persian, Exotic Shorthair, British Shorthair, British Longhair, Selkirk Rex, Maine Coon,, Chartreux, Ragdoll, Birman Abyssinian, Somali, Siamese, Cornish Rex, Oriental, Bengal, Balinese, Tonkinese, Peterbald, Singapura, Munchkin, Ocicat, American Wirehair, American Curl SMA Spinal Muscular Atrophy Maine Coon

8 We help breeders and veterinarians to : - Prevent and limit propagation of the most serious inherited diseases - Improve the health of dogs and cats Reliability Quality Innovation A high quality service : a team of advisors at your service 95% of very satisfied customers (survey 2014) Trust ANTAGENE quality approach : - Reliability of results above 99% - A reliable traceability from the order to the results - A permanent improvement of turnarounds - Innovation : more than 10 new DNA tests released each year - Our laboratory is certified ISO 9001 (by DEKRA) Order and get a DNA sampling kit From ANTAGENE 1 price : Fill-in the online certificate and print it price : contact us By phone : +33 (0) By contact@antagene.com 3 2 ANTAGENE sends you the DNA sampling kit To your home or directly to your vet The veterinarian performs the sampling He performs the cheek swab sample He authenticates the sampling certifi cate 4 Shipment of the sample to ANTAGENE Enclose the sampling certifi cate and the payment Résults 5 ANTAGENE provides you the results By postmail or on your online securised account (format depending on the price paid) Request a test from an existing ADN Your animal has already been tested in our laboratory : use the DNA of your animal stocked at ANTAGENE under condition DNA stocked is in sufficient quality/quantity A simple, fast and thrifty solution ANTAGENE - 6 Allée du Levant - CS La Tour de Salvagny - France Tél : +33 (0) Fax : +33 (0) contact@antagene.com