BRUCELLOSIS. Morning report 7/11/05 Andy Bomback
|
|
- Beryl Hall
- 5 years ago
- Views:
Transcription
1
2 BRUCELLOSIS Morning report 7/11/05 Andy Bomback
3 Also called undulant, Mediterranean, or Mata fever, brucellosis is an acute and chronic infection of the reticuloendothelial system gram negative facultative intracellular coccobacilli 4 species: B. melitensis, B. abortus, B. suis, B. canis
4 Humans acquire brucellosis from exposure to infected animals (direct contact with infected animal parts) or contaminated animal products (unpasteurized animal-milk products, such as raw milk, soft cheese, butter, and ice cream); the disease is also spread by inhalation of infected aerosolized particles
5
6 in US, most cases occur in slaughterhouse workers, farmers, veterinarians, and other animal handlers (including micro lab personnel)
7 The disease also presents in US Hispanic populations and is probably related to illegal importation of unpasteurized dairy products from Mexico Number of reported cases of human brucellosis in Hispanic and non- Hispanic California residents, by year,
8 The relationship between the disease and individual socioeconomic status is exemplified in the US, where programs to eradicate brucellosis have successfully limited the annual incidence of the disease, which now predominantly occurs in CA and TX (which account for >50% of US cases) with relatively high rates of incidence in NC, IL, FL, WY, IA, and AZ.
9 Country Azerbaijan Italy Mexico Turkey 11,427 11,462 10,742 15,510 17,553 14,435 USA
10 What the Republicans don t want you to know about brucellosis!!!
11 Clinical picture Brucellosis is a well documented cause of FUO with variable symptomatology fever (can be spiking and accompanied by rigors), sweats (often malodorous), malaise, anorexia, fatigue, weight loss, depression. Onset can be abrupt or insidious developing over several days to weeks. Despite multiple patient complaints, the physical exam findings (other than fever) are usually minimal to none can see minimal LAN and occasional HSM
12 Almost all organ systems can be involved with brucellosis localization of disease can cause focal symptoms or findings of 530 cases studies prospectively, 32% developed a complication; major risk factor for developing focal disease was duration of symptoms > 30 days
13 most common sites for localization: o Osteoarticular, especially sacroiliitis (20-30%) and peripheral arthritis o GU, especially epididymoorchitis (2-40% males) o Neurobrucellosis, usually presenting as meningitis (1-2%) o Endocarditis, left-sided and 2/3 on previously damaged valves (1%); remains the principle cause of mortality in the course of brucellosis and typically requires immediate surgical valve replacement o Hepatic abscess (1%)
14 Undiagnosed and untreated brucellosis can be symptomatic for months and some previously treated patients may relapse In the 1950 s, a syndrome called chronic brucellosis malaise, weakness, depression was a relatively common diagnosis; these patients likely represent the current population receiving diagnoses of chronic fatigue syndrome or chronic Lyme disease
15 MED H
16 Diagnostic work-up Consider brucellosis in patients with otherwise unexplained chronic fever and nonspecific complaints, particularly if there has been exposure to Brucella by contact with animal tissues or ingestion of unpasteurized milk or cheese.
17 WBC usually normal to low (can see pancytopenia); minor LFT abnormalities are fairly common Routine Labs
18 ideally, the diagnosis is made by isolation of the organism from cultures of blood or other sites (liver biopsies, bone marrow aspirates, pleural fluid, CSF) Cultures
19 classic serologic testing for brucellosis uses standard tube agglutination testing. In general, a single titer of >1:160 in the presence of compatible illness supports the diagnosis; titers should be repeated over the next 4-12 weeks, as a fourfold or greater increase or decrease provides even stronger evidence of the diagnosis other diagnostic serologic tests: ELISA, antibrucella Coombs, complement fixation, Rose Bengal agglutination Serologic Testing
20 P. C. freaking R. PCR identified 97% of fluid and tissue samples in patients with focal complications of brucellosis compared to only 29% by culture a combination of PCR-ELISA may turn out to be the most sensitive and specific method for diagnosis
21 Treatment After ingestion, the majority of brucellae are rapidly eliminated by phagolysosome fusion. Of those bacteria, 15-30% survive in gradually evolving brucellae-containing compartments, in which rapid acidification takes place. How this unique environment is formed is incompletely understood, but it is responsible for limiting antibiotic action and explains the discrepancy between in vitro studies and in vivo events.
22
23 All monotherapies have unacceptably high relapse rate, so combination regimens of antibiotics that can penetrate macrophages and act in the acidic intracellular environment are necessary.
24 1986 WHO guidelines for the treatment of brucellosis Regimen A: doxycycline 100 mg PO bid for 6 weeks + streptomycin 1 g IM qd for the first days Regimen B: doxycycline 100 mg PO bid + rifampin 600 to 900 mg (15 mg/kg) PO qd for 6 weeks
25 same relative efficacy of both regimens (including time to defervescence and relapse rate), but regimen B is obviously easier to implement other drugs (used in combination with doxycycline and/or rifampin): gentamicin, ofloxacin, ciprofloxacin, TMP- SMX
26 Relapses Most relapses occur within 3 months of stopping therapy and almost all within 6 months rate of relapse is about 10%. Relapses are often milder in severity than the initial disease and can be treated with a repeat course of the usual antibiotic regimen
27 Closing slide with picture of children to elicit sympathy from the audience
Outlines. Introduction Prevalence Resistance Clinical presentation Diagnosis Management Prevention Case presentation Achievements
Amal Meas Al-Anizi, PharmD Candidate KSU, Infectious Disease Rotation 2014 Outlines Introduction Prevalence Resistance Clinical presentation Diagnosis Management Prevention Case presentation Achievements
More informationBRUCELLOSIS BRUCELLOSIS. CPMP/4048/01, rev. 3 1/7 EMEA 2002
BRUCELLOSIS CPMP/4048/01, rev. 3 1/7 General points on treatment Four species are pathogenic to man: B. melitenis (acquired from goats), B. suis (pigs), B. abortus (cattle) and B. canis (dogs). The bacteria
More informationBrucellosis is a bacterial zoonosis transmitted directly or indirectly to humans from infected animals,
Definition Brucellosis is a bacterial zoonosis transmitted directly or indirectly to humans from infected animals, predominantly domesticated ruminants and swine. The disease is known colloquially as undulant
More informationP<0.05 ٢٠٠٧ ٣ ﺩﺪﻌﻟﺍ ﺮﺸﻋ ﺚﻟﺎﺜﻟﺍ ﺪﻠﺠﳌﺍ ﺔﻴﳌﺎﻌﻟﺍ ﺔﺤﺼﻟﺍ ﺔﻤﻈﻨﻣ ﻂﺳﻮﺘﳌﺍ ﻕﺮﺸﻟ ﺔﻴﺤﺼﻟﺍ ﺔﻠﺠﳌﺍ
72 144 P
More informationUpdate on brucellosis: therapeutic challenges
Update on brucellosis: therapeutic challenges Javier Solera To cite this version: Javier Solera. Update on brucellosis: therapeutic challenges. International Journal of Antimicrobial Agents, Elsevier,
More informationCase Study Brucellosis: 2001 & Case Study Brucellosis: 2001 & Case Study Brucellosis: 2001 & Case Study Brucellosis: 2001 & 2002
Potential Exposure to Attenuated Vaccine Strain Brucella abortus RB51 During a Laboratory Proficiency Test Harvey T. Holmes, PhD Chief, Laboratory Response Branch Division Bioterrorism Preparedness and
More informationBrucellosis in Kyrgyzstan
Centers for Disease Control and Prevention Case Studies in Applied Epidemiology No. 053-D11 Brucellosis in Kyrgyzstan Participant's Guide Learning Objectives After completing this case study, the participant
More informationOrganism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control Actions to Take
Brucellosis Overview Organism History Epidemiology Transmission Disease in Humans Disease in Animals Prevention and Control Actions to Take The Organism Brucella spp. Gram negative, coccobacilli bacteria
More informationSurveillance of animal brucellosis
Surveillance of animal brucellosis Assoc.Prof.Dr. Theera Rukkwamsuk Department of large Animal and Wildlife Clinical Science Faculty of Veterinary Medicine Kasetsart University Review of the epidemiology
More informationESCMID Online Lecture Library. by author
BRUCELLOSIS Hakan Erdem ESCMID Postgraduate Training Course September 2014, Izmir Presentation Plan The pathogen Epidemiology Transmission Diagnosis Clinical presentation Treatment Outcome HE-2 Aerobic
More informationJialin Jin Fudan University Huashan Hospital Department of infectious diseases
Jialin Jin Fudan University Huashan Hospital Department of infectious diseases Nov. 2014 It is term used as a convenient description for all phases of the disease caused by a bacteria called Brucella.
More informationMedical Bacteriology- Lecture 14. Gram negative coccobacilli. Zoonosis. Brucella. Yersinia. Francesiella
Medical Bacteriology- Lecture 14 Gram negative coccobacilli Zoonosis Brucella Yersinia Francesiella 1 Zoonosis: A disease, primarily of animals, which is transmitted to humans as a result of direct or
More informationAccidental Exposure to Cattle Brucellosis Vaccines in Wyoming, Montana, and Idaho Veterinarians
Accidental Exposure to Cattle Brucellosis Vaccines in Wyoming, Montana, and Idaho Veterinarians Kerry Pride, DVM, MPH, DACVPM Brucellosis Meeting April 3, 2013 Veterinary Occupational Exposure 1 needle
More informationThe Salmonella. Dr. Hala Al Daghisatni
1 Dr. Hala Al Daghisatni The Salmonella Salmonellae are often pathogenic for humans or animals when acquired by the oral route. They are transmitted from animals and animal products to humans, where they
More informationBiological Threat Fact Sheets
Biological Threat Fact Sheets Anthrax Agent: Bacillus anthracis There are three clinical forms of B. anthracis which are determined by route of entry: Pulmonary or Inhalation BT implications Cutaneous
More informationRELAPSED HUMAN BRUCELLOSIS AND RELATED RISK FACTORS
Original Article RELAPSED HUMAN BRUCELLOSIS AND RELATED RISK FACTORS Syed Muhammad Alavi 1, Syed Mohammad Reza Alavi 2, Leil Alavi 3 ABSTRACT Objectives: To determine risk factors of relapse among outpatient
More informationENTERIC BACTERIA. 1) salmonella. Continuation of the Enteric bacteria : A) We have mentioned the first group of salmonella (salmonella enterica ):
Continuation of the Enteric bacteria : ENTERIC BACTERIA 1) salmonella A) We have mentioned the first group of salmonella (salmonella enterica ): Salmonella is an obligate pathogen ; food poisoning due
More informationCentral Nervous System Infections
Central Nervous System Infections Meningitis Treatment Bacterial meningitis is a MEDICAL EMERGENCY. ANTIBIOTICS SHOULD BE STARTED AS SOON AS THE POSSIBILITY OF BACTERIAL MENINGITIS BECOMES EVIDENT, IDEALLY
More informationCHAPTER - I INTRODUCTION
CHAPTER - I INTRODUCTION Zoonotic infections are infections which are naturally transmitted between vertebrate animals and man, with or without an arthropod intermediate. Zoonotic infections represent
More informationThe Brucellae, Yersinia and Leptospira. By : Nader Alaridah MD, PhD
The Brucellae, Yersinia and Leptospira By : Nader Alaridah MD, PhD THE BRUCELLAE The brucellae are obligate parasites of animals and humans and are characteristically located intracellularly. They are
More informationClinical Manifestations and Treatment of Plague Dr. Jacky Chan. Associate Consultant Infectious Disease Centre, PMH
Clinical Manifestations and Treatment of Plague Dr. Jacky Chan Associate Consultant Infectious Disease Centre, PMH Update of plague outbreak situation in Madagascar A large outbreak since 1 Aug 2017 As
More informationFood safety related to camelids products: Brucellosis and its impact on Public Health and the consumers as an example
DIRECCION GENERAL DE LABORATORIOS Y CONTROL TECNICO Food safety related to camelids products: Brucellosis and its impact on Public Health and the consumers as an example Third Global Conference of OIE
More informationEffective host defense depends mainly upon cell-mediated immunity.
Brucella G.G. Alton J.R.L. Forsyth General Concepts Clinical Manifestations Brucellosis is a severe acute febrile disease caused by bacteria of the genus Brucella. Relapses are not uncommon; focal lesions
More informationClassificatie: intern
Classificatie: intern Animal Health Service Deventer Jet Mars part 1: Paratuberculosis ParaTB approach In the NL: control program, not an eradication program Quality of dairy products as starting point
More informationI n v e s t i g at i o n o f t h e s p r e a d o f b r u c e l l o s i s a m o n g
S u rve i ll a n c e a n d o u t b r e a k r e p o r t s I n v e s t i g at i o n o f t h e s p r e a d o f b r u c e l l o s i s a m o n g h u m a n a n d a n i m a l p o p u l at i o n s i n s o u t
More informationEnteric Bacteria. Prof. Dr. Asem Shehabi Faculty of Medicine University of Jordan
Enteric Bacteria Prof. Dr. Asem Shehabi Faculty of Medicine University of Jordan Enteric Bacteria General Characteristics: Gram-ve Bacilli, Facultative Anaerobes, Intestinal Normal Flora.. Humans, Animals,
More informationGuideline for Prevention of Brucellosis in Meat Packing Plant Workers
Guideline for Prevention of Brucellosis in Meat Packing Plant Workers Introduction Brucellosis is a disease which may spread from animals to man. There is no evidence for person to person transmission.
More informationEPIDEMIOLOGY OF BRUCELLOSIS IN HIGH RISK GROUP & PUO PATIENTS OF WESTERN RAJASTHAN
ORIGINAL ARTICLE. EPIDEMIOLOGY OF BRUCELLOSIS IN HIGH RISK GROUP & PUO PATIENTS OF WESTERN RAJASTHAN Prabhu Prakash 1, Suman Bhansali 2, Ekta Gupta 3, Dinesh Kothari 4, Arvind Mathur 5, Sneha Ambuwani
More informationDISEASE DETECTION OF BRUCELLOSIS IN GOAT POPULATION IN NEGERI SEMBILAN, MALAYSIA. Abstract
7 th Proceedings of the Seminar in Veterinary Sciences, 27 February 02 March 2012 DISEASE DETECTION OF BRUCELLOSIS IN GOAT POPULATION IN NEGERI SEMBILAN, MALAYSIA Siti Sumaiyah Mohd Yusof, 1,3 Abd. Wahid
More informationWe are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists. International authors and editors
We are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists 3,800 116,000 120M Open access books available International authors and editors Downloads Our
More informationSentinel Level Laboratory Protocols
Sentinel Level Laboratory Protocols Melissa Bossie, MT (ASCP), CLS (NCA), M. S. Sentinel Laboratory Training 1 Sentinel Laboratory Training 2 Anthrax Is a zoonotic disease in animals Spores can survive
More informationNew Insights into the Treatment of Leishmaniasis
New Insights into the Treatment of Leishmaniasis Eric Zini Snow meeting, 14 March 2009 Few drugs available for dogs Initially developed to treat human leishmaniasis, later adopted in dogs None eradicates
More informationFederal Expert Select Agent Panel (FESAP) Deliberations
Federal Expert Select Agent Panel (FESAP) Deliberations FESAP and Biennial Review Established in 2010 and tasked with policy issues relevant to the security of biological select agents and toxins Per recommendations
More informationCoccidioidomycosis Nothing to disclose
Coccidioidomycosis Nothing to disclose Disclosure Greg Melcher, M.D. Professor of Clinical Medicine Division of HIV, ID and Global Medicine Zuckerman San Francisco General Hospital University of California,
More informationGianluca Russo, MD, PhD. Brucellosis
Gianluca Russo, MD, PhD Brucellosis Generality Epidemiology of brucellosis - is the most common bacterial zoonosis: > 500.000 new cases annually and prevalence rates in some countries exceeding ten cases
More informationHuman brucellosis: An evaluation of antibiotics in the treatment of brucellosis
Postgrad. med. J. (August 1967) 43, 520-526. Human brucellosis: An evaluation of antibiotics in the treatment of brucellosis JoHN RIZZO-NAUDI M.D., B.Sc., M.R.C.P.(Ed.) Lecturer in Medicine, Royal University
More informationCefazolin vs. Antistaphyloccal Penicillins: The Great Debate
Cefazolin vs. Antistaphyloccal Penicillins: The Great Debate Annie Heble, PharmD PGY2 Pediatric Pharmacy Resident Children s Hospital Colorado Microbiology Rounds March 22, 2017 Image Source: Buck cartoons
More informationWisconsin Bovine TB Update
Wisconsin Bovine TB Update Dr. Darlene Konkle Assistant State Veterinarian Wisconsin Department of Agriculture, Trade and Consumer Protection (DATCP) Division of Animal Health Mycobacterium species M.
More informationClinical manifestations of brucellosis and leptospirosis
Clinical manifestations of brucellosis and leptospirosis Department of Internal Medicine Division of Infectious Diseases Medical University of Vienna Fever after sexual intercourse admissional status 25-year
More information64 year old retired male (former millwright)
Cheryl Main 2013 None! 64 year old retired male (former millwright) Past medical history Type II Diabetes with Chronic Kidney Disease Sjogren s syndrome treated with plaquenil Autoimmune hemolytic anemia
More informationCHALLENGE SET EXERCISE FALL 2008
CHALLENGE SET EXERCISE FALL 2008 Scenario 1 Fifteen year old female presents to clinic with cat bite to hand. Aerobic wound culture ordered No Gram Stain Organism 1 Characteristics Growth on Blood and
More informationCircular 298 September 1989 Alabama Agricultural Experiment Station Auburn University Lowell T. Frobish, Director Auburn University, Alabama
z SF f. i" f: Y~ c;;; -- Af --- Circular 298 September 1989 Alabama Agricultural Experiment Station Auburn University Lowell T. Frobish, Director Auburn University, Alabama Information contained herein
More informationTularemia. Information for Health Care Providers. Physicians D Nurses D Laboratory Personnel D Infection Control Practitioners
Tularemia Information for Health Care Providers Physicians D Nurses D Laboratory Personnel D Infection Control Practitioners Tularemia Caused by Francisella tularensis, a small, pleomorphic, gram-negative
More informationNew Mexico Department of Agriculture
Veterinary Diagnostic Services New Mexico Department of Agriculture The New Mexico Organic Farming Conference 2018 New Mexico Scientific Laboratories New Mexico Department of Agriculture Veterinary Diagnostic
More informationA collaborative effortan investigation of suspect canine brucellosis
A collaborative effortan investigation of suspect canine brucellosis NJDOH Regional Epidemiologist: Sonya E. Frontin, MPH Warren County Health Department Public Health Planner: Sarah Perramant, MPH April
More informationCanine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys
Canine Anaplasmosis Anaplasma phagocytophilum Anaplasma platys It takes just hours for an infected tick to transmit Anaplasma organisms to a dog. What is canine anaplasmosis? Canine anaplasmosis is a disease
More informationInternational Journal of Health Sciences and Research ISSN:
International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Original Research Article Brucellosis! An Unusual Etiology in PUO! Satyajeet K Pawar 1*, M.V. Ghorpade 2, R.D. Totad
More informationProcedures for the Taking of Prevention and Eradication Measures of Brucellosis in Bovine Animals
Republic of Latvia Cabinet Regulation No. 881 Adopted 18 December 2012 Procedures for the Taking of Prevention and Eradication Measures of Brucellosis in Bovine Animals Issued in accordance with Section
More informationDiabetic Foot Infection. Dr David Orr Consultant Microbiologist Lancashire Teaching Hospitals
Diabetic Foot Infection Dr David Orr Consultant Microbiologist Lancashire Teaching Hospitals History of previous amputation [odds ratio (OR)=19.9, P=.01], Peripheral vascular disease (OR=5.5, P=.007)
More informationSeroprevalence of Brucellosis and Risk Factors Related to High Risk Occupational Groups in Kazeroon, South of Iran
Original Article Seroprevalence of Brucellosis and Risk Factors Related to High Risk Occupational Groups in Kazeroon, South of Iran S Beheshti, 1 GR Rezaian, 1 F Azad, 1 Z Faghiri, 1 F Taheri 2 Abstract
More informationAntimicrobial Stewardship in Continuing Care. Urinary Tract Infections Clinical Checklist
Antimicrobial Stewardship in Continuing Care Urinary Tract Infections Clinical Checklist December 2014 What is Antimicrobial Stewardship? Using the: right antimicrobial agent for a given diagnosis at the
More informationEPIDEMIOLOGY REPORT. Bovine brucellosis: what is going on?
EPIDEMIOLOGY REPORT VETERINARY SERVICES October 2016 Volume 8 Issue 10 Bovine brucellosis: what is going on? In the veterinary community, brucellosis is a well-known zoonotic disease and the importance
More informationANTHRAX. INHALATION, INTESTINAL and CUTANEOUS ANTHRAX
INHALATION, INTESTINAL and CUTANEOUS ANTHRAX CPMP/4048/01, rev. 3 1/7 General points on treatment Anthrax is an acute infectious disease caused by Bacillus anthracis, that may be infecting man via cutaneous
More informationTick-borne Disease Testing in Shelters What Does that Blue Dot Really Mean?
Tick-borne Disease Testing in Shelters What Does that Blue Dot Really Mean? 2017 ASPCA. All Rights Reserved. Your Presenter Stephanie Janeczko, DVM, MS, DABVP, CAWA Senior Director of Shelter Medical Programs
More informationRational management of community acquired infections
Rational management of community acquired infections Dr Tanu Singhal MD, MSc Consultant Pediatrics and Infectious Disease Kokilaben Dhirubhai Ambani Hospital, Mumbai Why is rational management needed?
More informationA STUDY ON THE SEROPREVALENCE OF BRUCELLOSIS IN HUMAN AND GOAT POPULATIONS OF DISTRICT BHIMBER, AZAD JAMMU AND KASHMIR ABSTRACT
Din et al. The Journal of Animal and Plant Sciences, 23(1 Suppl.): 2013, J Anim Page: Plant 113-118 Sci, 23(Sup 1): 2013 ISSN: 1018-7081 A STUDY ON THE SEROPREVALENCE OF BRUCELLOSIS IN HUMAN AND GOAT POPULATIONS
More informationInteractive session: adapting to antibiogram. Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe
Interactive session: adapting to antibiogram Thong Phe Heng Vengchhun Felix Leclerc Erika Vlieghe Case 1 63 y old woman Dx: urosepsis? After 2 d: intermediate result: Gram-negative bacilli Empiric antibiotic
More informationAssociation between Brucella melitensis DNA and Brucella spp. antibodies
CVI Accepts, published online ahead of print on 16 March 2011 Clin. Vaccine Immunol. doi:10.1128/cvi.00011-11 Copyright 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All
More informationPerichondritis: Source: UpToDate Ciprofloxacin 10 mg/kg/dose PO (max 500 mg/dose) BID Inpatient: Ceftazidime 50 mg/kg/dose q8 hours IV
Empiric Antibiotics for Pediatric Infections Seen in ED NOTE: Choice of empiric antibiotic therapy must take into account local pathogen frequency and resistance patterns, individual patient characteristics,
More informationEpidemiology - Animal Tracing Exercise. Gregory Ramos DVM, MPVM Area Epidemiology Officer USDA/APHIS/VS
Epidemiology - Animal Tracing Exercise Gregory Ramos DVM, MPVM Area Epidemiology Officer USDA/APHIS/VS Thanks to. Tanya Beaucaire AHT -- USDA Bill Grigsby AHT USDA Dennis Wilson DVM, MPVM, PhD -- CDFA
More informationSuggested vector-borne disease screening guidelines
Suggested vector-borne disease screening guidelines SNAP Dx Test Screen your dog every year with the SNAP Dx Test to detect exposure to pathogens that cause heartworm disease, ehrlichiosis, Lyme disease
More informationFeline zoonoses. Institutional Animal Care and Use Committee 12/09
Feline zoonoses Institutional Animal Care and Use Committee 12/09 Cat scratch disease Bacterial infection caused by Bartonella henselae Associated with a cat bite or scratch Infection at point of injury,
More informationFungal Disease. What is a fungus?
Fungal Disease What is a fungus? A fungus is a living organism. It goes through a complicated life cycle and is able to spread in the environment by producing large numbers of spores that are easily dispersed
More informationSignificance of brucellosis in backache patients
Original article: Significance of brucellosis in backache patients (1) Dr Ravindra S Mohite, (2)Dr Dhanashree Deshpande, ( 3)Dr V A Kulkarni, (4)Dr Pankaj Joshi, (5)Dr R D Kulkarni, (6) Dr Shilpa Shah,
More informationWelcome to Pathogen Group 9
Welcome to Pathogen Group 9 Yersinia pestis Francisella tularensis Borrelia burgdorferi Rickettsia rickettsii Rickettsia prowazekii Acinetobacter baumannii Yersinia pestis: Plague gram negative oval bacillus,
More information11-ID-10. Committee: Infectious Disease. Title: Creation of a National Campylobacteriosis Case Definition
11-ID-10 Committee: Infectious Disease Title: Creation of a National Campylobacteriosis Case Definition I. Statement of the Problem Although campylobacteriosis is not nationally-notifiable, it is a disease
More informationAn Outbreak of Brucella melitensis among Goat Farmers in Thailand, December 2009
An Outbreak of Brucella melitensis among Goat Farmers in Thailand, December 29 Vilaiporn Wongphruksasoong 1,*, Santayakorn S 1, Sitthi W 1, Chuxnum T 1, Pipatjaturong N 2, Kunthu A 3, Phuyathon B 4, Prasert
More informationAustralian and New Zealand College of Veterinary Scientists. Membership Examination. Small Animal Medicine Paper 1
Australian and New Zealand College of Veterinary Scientists Membership Examination June 2015 Small Animal Medicine Paper 1 Perusal time: Fifteen (15) minutes Time allowed: Two (2) hours after perusal Answer
More informationHYDATID CYST DISEASE
HYDATID CYST DISEASE Hydatid disease, also called hydatidosis or echinococcosis, is a cystforming disease resulting from an infection with the metacestode, or larval form, of parasitic dog tapeworms from
More informationRisk Factors for Relapse of Human Brucellosis
Global Journal of Health Science; Vol. 8, No. 7; 206 ISSN 96-9736 E-ISSN 96-9744 Published by Canadian Center of Science and Education Risk Factors for Relapse of Human Brucellosis Mohammad Reza Hasanjani
More informationSeroprevalence of human brucellosis in Erbil city
Seroprevalence of human brucellosis in Erbil city Received : 10/8/2011 Accepted: 7/1/2012 Dlsoz Kareem Rasul* Isam Yousif Mansoor * Abstract Background and objectives: Brucellosis is an acute or chronic
More informationCLINICAL USE OF AMINOGLYCOSIDES AND FLUOROQUINOLONES
CLINICAL USE OF AMINOGLYCOSIDES AND FLUOROQUINOLONES Douglas Black, Pharm.D. Associate Professor School of Pharmacy University of Washington dblack@u.washington.edu THE AMINOGLYCOSIDES: 1944-1975 Drug
More informationSalmonella. Serological. Salmonella. food poisoning. Use of pasteurized milk and milk products Improvement of hygiene. Proper storage of foods
Character Habitat Serological Pathogenicity Salmonella food poisoning Salmonella Gram ve facultative anaerobes, non lactose fermenter bacilli Intestinal tracts of humans and animals Salmonella: >1000 species
More informationSurveillance of Brucella Antibodies in Camels of the Eastern Region of Abu Dhabi, United Arab Emirates
Proceedings of the Third Annual Meeting for Animal Production UnderArid Conditions, Vol. 1: 160-166 1998 United Arab Emirates University. Surveillance of Brucella Antibodies in Camels of the Eastern Region
More informationWhat s Your Diagnosis? By Sohaila Jafarian, Class of 2018
Signalment: Greeley, 3 yo MC DSH Presenting Complaint: ADR History: What s Your Diagnosis? By Sohaila Jafarian, Class of 2018 Patient is an indoor/outdoor cat. Previously healthy and up to date on vaccines
More informationZoonoses in West Texas. Ken Waldrup, DVM, PhD Texas Department of State Health Services
Zoonoses in West Texas Ken Waldrup, DVM, PhD Texas Department of State Health Services Notifiable Zoonotic Diseases Arboviruses* Anthrax Brucellosis Bovine Tuberculosis Creutzfeldt-Jacob disease (variant)
More informationDisease Outbreak Investigation Protocol: Brucellosis Case Study MONOGRAPH
2. Disease Outbreak Investigation Protocol: Brucellosis Case Study MONOGRAPH Protocol for conducting an outbreak investigation A. Goals for outbreak investigation 1. Stop the occurrence of disease with
More informationChronic Brucellosis and Persistence of Brucella melitensis DNA
JOURNAL OF CLINICAL MICROBIOLOGY, July 2009, p. 2084 2089 Vol. 47, No. 7 0095-1137/09/$08.00 0 doi:10.1128/jcm.02159-08 Copyright 2009, American Society for Microbiology. All Rights Reserved. Chronic Brucellosis
More informationSee Important Reminder at the end of this policy for important regulatory and legal information.
Clinical Policy: Doxycycline Hyclate (Acticlate, Doryx), Doxycline (Oracea), Minocycline (Solodyn, Ximino) Reference Number: CP.CPA.120 Effective Date: 11.16.16 Last Review Date: 11.17 Line of Business:
More informationPublic Health Risks in Asia s Growing Dairy Sector
Public Health Risks in Asia s Growing Dairy Sector Joachim Otte (FAO, Bangkok) Dairy Asia Towards Sustainability Bangkok, Thailand, 22 May 2014 Building Bridges, Supporting Livelihoods Hazards and characteristics
More informationEUROPEAN COMMISSION HEALTH & CONSUMERS DIRECTORATE-GENERAL. Unit G5 - Veterinary Programmes
EUROPEAN COMMISSION HEALTH & CONSUMERS DIRECTORATE-GENERAL Unit G5 - Veterinary Programmes SANCO/10853/2012 Programmes for the eradication, control and monitoring of certain animal diseases and zoonoses
More informationClinical and therapeutic features of brucellosis: An 11-year study at a tertiary care hospital in Riyadh, Saudi Arabia
Tropical Biomedicine 34(4): 977 982 (2017) Clinical and therapeutic features of brucellosis: An 11-year study at a tertiary care hospital in Riyadh, Saudi Arabia Somily, A.M. 1, Alahaideb, A. 2, Ridha,
More informationIntroduction to Chemotherapeutic Agents. Munir Gharaibeh MD, PhD, MHPE School of Medicine, The university of Jordan November 2018
Introduction to Chemotherapeutic Agents Munir Gharaibeh MD, PhD, MHPE School of Medicine, The university of Jordan November 2018 Antimicrobial Agents Substances that kill bacteria without harming the host.
More informationHow to talk to clients about heartworm disease
Client Communication How to talk to clients about heartworm disease Detecting heartworm infection early generally allows for a faster and more effective response to treatment. Answers to pet owners most
More informationManagement of Native Valve
Management of Native Valve Infective Endocarditis 2005 AHA 2015 Baddour LM, et al. Circulation. 2015;132(15):1435-86 2009 ESC 2015 Habib G, et al. Eur Heart J. 2015;36(44):3075-128 ESC 2015: Endocarditis
More informationCanine and Feline Distemper. Description. The following chart indicates the animals which are susceptible to infection by canine and feline distemp
Canine and Feline Distemper Description Canine and feline distemper are diseases affecting many wild and domestic carnivo The following chart indicates the animals which are susceptible to infection by
More informationMicrobial Hazards in Dairy Industry Ceren Zeytinci
Ceren Zeytinci cerenzeytinci@hotmail.com 1 After completing this course, the participants know about the microorganisms that are threating the dairy industry. They are capable of eliminating and preventing
More informationSubacute Adenitis. Ann M. Loeffler, MD
Subacute Adenitis Ann M. Loeffler, MD Lymphadenitis Swelling and hyperplasia of sinusoidal lining cells Infiltration of leukocytes +/- abscess formation Granulomatous or non-granulomatous Pyogenic adenitis
More informationThree patients with fever and rash after a stay in Morocco: infection with Rickettsia conorii
Three patients with fever and rash after a stay in Morocco: infection with Rickettsia conorii Stylemans D 1, Mertens R 1, Seyler L 1, Piérard D 2, Lacor P 1 1. Department of Internal Medicine, UZ Brussel
More informationA rapid test for evaluating B. melitensis infection prevalence in an Alpine ibex (Capra ibex) reservoir in the French Alps
European Union Reference Laboratory for Brucellosis A rapid test for evaluating B. melitensis infection prevalence in an Alpine ibex (Capra ibex) reservoir in the French Alps EU Reference Laboratory for
More informationLyme disease: diagnosis and management
National Institute for Health and Care Excellence Final Lyme disease: diagnosis and management [D] Evidence review for the management of erythema migrans NICE guideline 95 Evidence review April 2018 Final
More informationZoonotic Diseases. Department of Tropical Diseases. Faculty of Veterinary Science. Make today matter
Faculty of Veterinary Science Fakulteit Veeartsenykunde Lefapha la Diseanse tša Bongakadiruiwa Zoonotic Diseases Department of Tropical Diseases Make today matter I 3 Anthrax 5 Bovine Tuberculosis 7 Brucellosis
More informationPIGEON FEVER (Corynebacterium pseudotuberculosis Infection)
PIGEON FEVER (Corynebacterium pseudotuberculosis Infection) Definition Clinical Signs Incubation Period Risk Factors Transmission Diagnostic Sampling, Testing and Handling Environmental Persistence Specific
More informationDiscuss the reservoirs and vectors of the causative organisms of Lyme disease and other tick-borne
Brian S. Murphy, MD, MPH November 5, 2008 40th Annual Family Medicine Review Discuss the reservoirs and vectors of the causative organisms of Lyme disease and other tick-borne diseases Discuss the distribution
More informationEVALUATION AND IMPORTANCE OF SELECTED MICROBIOLOGICAL METHODS IN THE DIAGNOSIS OF HUMAN BRUCELLOSIS
& EVALUATION AND IMPORTANCE OF SELECTED MICROBIOLOGICAL METHODS IN THE DIAGNOSIS OF HUMAN BRUCELLOSIS Maida Šiširak*, Mirsada Hukić Institute of Microbiology, Immunology and Parasitology, University of
More informationINVESTIGATING EFFICIENCY OF PCR METHOD IN DIAGNOSIS OF BRUCELLOSIS, COMPARING TO SEROLOGIC METHODS
ISSN: 0976-2876 (Print) ISSN: 2250-0138(Online) INVESTIGATING EFFICIENCY OF PCR METHOD IN DIAGNOSIS OF BRUCELLOSIS, COMPARING TO SEROLOGIC METHODS HOJAT AHMADI a, EHSAN HOSSEINI b1, KEYVAN HOMAYONIKEYSAMI
More informationSepticaemia Definitions 1
Septicaemia Definitions 1 Term Definition Bacteraemia Systemic Inflammatory response (SIRS) Sepsis Bacteria that can be cultured from the blood stream The systemic response to a wide range of stresses.
More informationGastric Dilatation-Volvulus
Gastric Dilatation-Volvulus The term "ACVS Diplomate" refers to a veterinarian who has been board certified in veterinary surgery. Only veterinarians who have successfully completed the certification requirements
More informationEUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH
ejpmr, 2018,5(6), 642-646 EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH www.ejpmr.com SJIF Impact Factor 4.897 Research Article ISSN 2394-3211 EJPMR KNOWLEDGE, ATTITUDE AND PRACTICE (KAP) ASSOCIATED
More informationAbortions and causes of death in newborn sheep and goats
Abortions and causes of death in newborn sheep and goats Debrah Mohale What is abortion? Abortion is the result of a disturbance in the functioning of the afterbirth (placenta). This causes the premature
More information