Fundamentals of Pharmacology for Veterinary Technicians Chapter 1

Transcription

1 DIN Each ml contains / chaque ml contient: Xylazine: 20 mg (Present as xylazine hydrochloride / présent comme chlorhydrate de xylazine) Veterinary use only / usage vétérinaire seulement Bayer, Bayer Cross, and Rompun are registered trademarks of Bayer AG, used under licence. Bayer, la Croix Bayer et Rompun sont des marques déposées de Bayer AG utilisées 20 ml sous licence , R B7A9 Lot: Exp.: Figure 5-1

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16 Trade name Generic name Warnings Description or Composition Statements Adverse reactions Clinical Pharmacology Indications and usage Dosage and administration Storage How supplied Contraindications Precautions Figure 5-6

17 Trade name Controlled substance indication Generic name Indications and usage Description Clinical pharmacology Safety or overdosage Dosage and administration Precautions/storage Contraindications Warnings Adverse reactions How supplied Figure 5-7

18 Telephone (410) P.O. Box Owner s Name Animals Name and species Address of Owner SMART ANIMAL HOSPITAL Dr. Joyce Smart Baltimore, MD Age of Animal Date Rx: Name of Drug Strength of Drug Quantity Sig.: Instructions to Patient Refills _number_ Figure 5-8

19 SMART ANIMAL HOSPITAL SMART ANIMAL HOSPITAL Figure 5-9

20 For the Eye Please Phone Ahead for Refills FOR THE EAR Shake Well Before Using Keep Refrigerated Keep Out of the Reach of Children Give By Mouth Only This prescription cannot be refilled without an exam. FOR VETERINARY USE ONLY KEEP OUT OF CHILDREN S REACH Give with Food May Cause Drowsiness REFRIGERATE ONLY DO NOT FREEZE! External Use Only Do Not Use For Cats IMPORTANT! Finish all medication unless otherwise directed by prescriber. Please phone if condition worsens WARNING! NOT FOR HUMAN USE For the Nose Federal law prohibits the transfer of this drug to any patient other than the patient for whom it was prescribed. Store at Room Temperature DO NOT REFRIGERATE! Figure 5-10

21 SMART ANIMAL HOSPITAL/Dr. J. Smart P.O. Box Baltimore, MD Figure 5-11

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23 Client: Patient: Veterinary Pharmaceutical Data Sheet Brookside Veterinary Clinic, S.C Eastern Ave. Plymouth, WI Josette Svitter Milagro Canine/Retriever, Labrador Mix/Neutered Male Your animal has been prescribed deracoxib. Please read the information below to make sure you fully understand the purpose and proper use of deracoxib. Your veterinarian has requested that you give the prescription (deracoxib) to your animal as follows: GIVE 1/2 TABLET ORALLY EVERY 24 HOURS FOR 30 DAYS. Pharmaceutical: Deracoxib General INDICATIONS FOR USE: Your veterinarian has prescribed this medication for the relief of pain in dogs. PRECAUTIONS: As with any medication, there are precautions and side effects associated with their use. This is sometimes complicated by the fact that many of the drugs used in veterinary patients are human drugs that have not been studied for use in animals. Some of these so called extra label drugs have been used for years in veterinary medicine and side effects and precautions listed are those that have been compiled by experience with these drugs. In cases where veterinary experience is limited, human precautions and side effects have been listed. In any event, many of the side effects listed have occurred very rarely but have been included for your information and awareness. The potential benefit of the use of the drug must be weighed against the information known about the risk of the use of the drug. Your veterinarian has the best interest of your animal in mind and will help you make an informed decision about their treatment. *It should not be used in patients with known sensitivity to this type of drug non steroidal anti inflammatory drug. Dogs with bleeding disorders, GI ulcers, liver disease or pre existing renal impairment may be at a greater risk for serious side effects. Use only when benefit outweighs the risk during pregnancy as safety studies have not been done. It is recommended to give the lowest effective dose as infrequently as is necessary to control pain. Baseline bloodwork and urine is recommended to assess the general health of the patient prior to starting this drug. Periodic bloodwork to monitor this drug s effect on the body is advised if long term therapy is required. SIDE EFFECTS: GI effects are the most common side effect nausea, loss of appetite, vomiting, stomach ulceration, soft stool or diarrhea. Other possible side effects include lethargy, restlessness, aggression, itchiness, hair loss, skin reactions, hives, redness of skin, low albumen, increased water consumption and urination, neurologic signs, seizures and balance disorders. Liver damage, jaundice and/or kidney disease can occur and dogs with pre existing conditions and geriatric dogs seem to be at greater risk. Serious blood changes such as immune mediated hemolytic anemia and low platelet count are also possible. If any reaction becomes severe it may result in the death of the animal. If your animal experiences any of the above side effects, any unusual bleeding or bruising or any unusual symptoms discontinue use and contact your veterinarian. Notify your veterinarian if your animal s condition does not improve or worsens despite this treatment. APPROVED SPECIES: The use of this medication in animals other than dogs is considered extra label as there is no product available for other species. DRUG INTERACTIONS: If your animal has been prescribed any other medication, including aspirin, steroids or other anti inflammatory medication such as Etogesic, Rimadyl or Zubrin please discuss this with your veterinarian as interactions may occur. B OVERDOSE: Keep all drugs out of the reach of children. In case of accidental exposure contact your local health professional immediately. Keep all drugs out of the reach of pets. Overdose of any medication can cause serious adverse effects. In case of accidental ingestion or overdose, contact your veterinarian or the National Animal Poison Control Center at immediately. Figure 5-12B

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25 Brookside Veterinary Clinic, S.C Eastern Ave. Plymouth, WI (920) PURCHASE ORDER A Vendor Name: Merial Limited PO Number: 363 Contact: Phone1 Status: Partial Account No.: Date: 3/3/20XX Vendor Phone: (888) Ext.: Reference No.: Item ID Description Quantity Unit Vendor Item ID Unit Cost Extended Cost RABVAC Rabies Vaccine dose ST D $ $ LYMEVAC Lyme Vaccine dose ST D $ $1, Total Cost: $1, Figure 5-14A

26 2010 Olympic Drive Athens, GA Packing List NOT AN INVOICE Page 1 of 1 PURCHASE ORDER NUMBER: N SHIP FROM MEM ROUTING ORDER NO. ORDER DATE SHIP DATE 036 / UPS Ground - BIO /24/20XX 12:44 02/24/20XX SHIP TO: Brookside Veterinary Center SC 2712 Eastern Ave. Plymouth, WI BILL TO: Brookside Veterinary Center SC 2712 Eastern Ave. Plymouth, WI PRODUCT NO./DESCRIPTION LOT NO RECOMBITEK LYME (50X1DS) IMRAB 3 TF (50X1DS) 18090A QTY ORDERED 2 2 QTY SHIPPED 2 2 LIST PRICE EXTENSION DISCOUNT NET APPLIED AMOUNT R E M A R KS TOTAL VALUE OF SHIPMENT TOTAL PIECES: $1, B Please report damages or shipping errors immediately upon receipt at Figure 5-14B

27 2010 Olympic Dr. Atlanta GA LIM Dom Invoice Page 1 of 1 For Questions or Inquiries Please Call Phone #: Fax : CUST. NO. ORDER NO. PURCHASE ORDER NO. SHIP DATE INVOICE NO. INVOICE DATE N /24/20XX /24/20XX SOLD TO SHIP TO 1 1 SP Brookside Veterinary Center SC 2712 Eastern Ave Plymouth WI BROOKSIDE VETERINARY CENTER SC 2712 EASTERN AVE PLYMOUTH WI PRODUCT DESCRIPTION ITEM # SIZE QTY IMRAB 3 TF (50X1DS) TRY 2 RECOMBITEK LYME (50X1DS) TRY 2 LIST PRICE $94.50 $ EXTENSION $ $0.00 $ $1, DISCOUNT APPLIED NET AMOUNT $0.00 $1, SUB-TOTAL $1, TAX $74.05 FREIGHT $0.00 TOTAL $1, PAYMENT TERMS IF PAID BY PAY AMT BELOW INV. DUE TOTAL DUE 09 Vaccine Pref Customer Terms 05/20/2009 $1, REASON: LICENSE: DETACH AND RETURN CHECK CREDIT CARD USING FOR PAYMENT AND FILL OUT BELOW CARD NUMBER MasterCard VISA AMERICAN EXPRESS AMOUNT Customer: BROOKSIDE VETERINARY CUSTOMER NO.: INVOICE NO.: INVOICE DUE.: INVOICE TOTAL.: AMOUNT PAID: /20/20XX $1, NAME ON CARD (PLEASE PRINT) AMOUNT SIGNATURE INVOICE DATE ACCOUNT # PAY THIS AMOUNT 02/24/20XX $1, PLEASE CHECK IF CHANGE OF ADDRESS AND FILL OUT REVERSE SIDE C THANK YOU FOR YOUR BUSINESS! Figure 5-14C

28 Inventory Evaluation Report Sorted by Item Description Item: ANAMAX Animax Ointment 15 Ml Class: I Dermatology Meds. Buy/Sell Ratio: On Hand Loc/Total: On Order: On Backorder: Buy UOM: Last Purchase Date: Base Pricing Info: 1 tube to 1.00 tube 19.00/19.00 tube tube 0.00 tube tube 3/4/2009 $13.88 Dispensing Fee: Lead Time: Reorder Point: Reorder Quantity: Overstock Point: Markup: $ tube tube tube 154% Sell UOM: Prices Auto Calculate: Minimum Price: Primary Vendor: Vendor Item ID: Location: tube Yes $0.00 Midwest Veterinary Supply ST D PHARM Item: ANTISED Antisedan Class: Y Sm. Ani. Anesthetic Agents Buy/Sell Ratio: On Hand Loc/Total: On Order: On Backorder: Buy UOM: Last Purchase Date: Base Pricing Info: 1 bottle to cc 44.00/44.00 cc 0.00 bottle 0.00 bottle bottle 1/2/2009 $24.95 Dispensing Fee: Lead Time: Reorder Point: Reorder Quantity: Overstock Point: Markup: $ cc 1.00 bottle cc 135% Sell UOM: Prices Auto Calculate: Minimum Price: Primary Vendor: Vendor Item ID: Location: Item: APOMOR Apomorphine 3 Mg Class: Y Sm. Ani. Anesthetic Agents Buy/Sell Ratio: On Hand Loc/Total: On Order: On Backorder: Buy UOM: Last Purchase Date: Base Pricing Info: 1 bottle to /11.00 capsule 0.00 bottle 0.00 bottle bottle 4/7/2004 $5.83 Dispensing Fee: Lead Time: Reorder Point: Reorder Quantity: Overstock Point: Markup: $ % Sell UOM: Prices Auto Calculate: Minimum Price: Primary Vendor: Vendor Item ID: Location: cc Yes $0.00 Pfizer Animal Health ST D TREATME capsule Yes $0.00 Island Pharmacy STD TREATME Item: TEARS Artificial Tears 3.5 Gm Class: Q Ophthalmics Buy/Sell Ratio: On Hand Loc/Total: On Order: On Backorder: Buy UOM: Last Purchase Date: Base Pricing Info: 1 tube to 1.00 tube 58.00/58.00 tube tube 0.00 tube tube 3/11/2009 $7.03 Dispensing Fee: Lead Time: Reorder Point: Reorder Quantity: Overstock Point: Markup: $ tube 6.00 tube tube 191% Sell UOM: Prices Auto Calculate: Minimum Price: Primary Vendor: Vendor Item ID: Location: tube Yes $0.00 Midwest Veterinary Supply PHARM Item: ATROPIN Atropine Ophthalmic 1%so Class: Q Ophthalmics Buy/Sell Ratio: On Hand Loc/Total: On Order: On Backorder: Buy UOM: Last Purchase Date: Base Pricing Info: 1 bottle to 1.00 bottle 22.00/22.00 bottle 0.00 bottle 0.00 bottle bottle 3/24/2008 $6.58 Dispensing Fee: Lead Time: Reorder Point: Reorder Quantity: Overstock Point: Markup: $ bottle 6.00 bottle bottle 143% Sell UOM: Prices Auto Calculate: Minimum Price: Primary Vendor: Vendor Item ID: Location: bottle Yes $0.00 Butler Co PHARM Date: 3/23/20XX Figure 5-15

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31 Table 5-1 Drug Identification Term Definition Example Chemical structure Diagram of the chemical arrangement of the drug H3C N O N Cl Chemical name Generic or nonproprietary name Trade or proprietary name The name of the drug based on its chemical structure The name assigned by the USAN, but not exclusive to a particular company The name picked by the company that is registered 7-chloro-1,3-dihydro- 1-methyl-5-phenyl-2H-1, 4-benzodiazepin-2-one diazepam Valium R or Valium Table 5-1

32 Table 5-2 Guidelines for Veterinary Prescribed Drugs and Veterinarian/Client/Patient Relationship Veterinary prescription drugs are labeled for use only by or on the order of a licensed veterinarian. Incidents involving the sale and use of prescription drugs without a prescription should be reported to the proper state authority and the U.S. FDA. Veterinary prescription drugs are to be used or prescribed only within the context of a VCPR. A VCPR exists when all of the following conditions have been met: The veterinarian has assumed responsibility for making clinical judgments regarding the health of the animal(s) and the need for medical treatment, and the client has agreed to follow the veterinarian s instructions. The veterinarian has sufficient knowledge of the animal(s) to initiate at least a general or preliminary diagnosis of the medical condition of the animal(s). This means that the veterinarian has recently seen and is personally acquainted with the keeping and care of the animal(s) by virtue of an examination of the animal(s) or by medically appropriate and timely visits to the premises where the animal(s) are kept. The veterinarian is readily available for follow-up evaluation, or has arranged for emergency coverage, in the event of adverse reactions or failure of the treatment regimen. Veterinary prescription drugs must be properly labeled before being dispensed. Appropriate dispensing and treatment records must be maintained. Veterinary prescription drugs should be dispensed only in quantities required for the treatment of the animal(s) for which the drugs are dispensed. Avoid unlimited refills of prescriptions or any other activity that might result in misuse of drugs. Any drug used in a manner not in accordance with its labeling (extra-label use) should be subjected to the same supervisory precautions that apply to veterinary prescription drugs. Table 5-2

33 Table 5-3 Pharmacology Abbreviations % ac ad lib bid BSA c cal cap cc cm conc D 5 dr ED W ED 50 Abbreviation Percent Meaning registered trade name when superscript by drug name before meals (ante cibum) as much as desired (ad libitum) twice daily (bis in die) body surface area with calorie capsule cubic centimeter (same as ml) centimeter concentration 5% dextrose in water dram; equal to 1/8 oz or 4 ml effective dose median effective dose fl o z fluid ounce g gal gr gt gtt hr IA IC ID IM IP IT IU IV kg km gram gallon grain; unit of weight approximately 65 mg drop (gutta) drops (guttae) hour intra-arterial intracardiac intradermal intramuscular intraperitoneal intratracheal international units intravenous kilogram kilometer (Continued) Table 5-3

34 Abbreviation L lb or # behind a number LD LD 50 LRS m mcg or μg med meq mg MIC MID ml MLD mm npo NS OTC oz p pc PDR ph po ppm PR prn pt q q12h q4h q6h q8h qd liter pound(s) lethal dose median lethal dose lactated Ringer s solution meter microgram minimal effective dose milliequivalent milligram Meaning minimum inhibitory concentration minimum infective dose milliliter (same as cc) minimum lethal dose millimeter (also used to mean muscles) nothing by mouth (non per os) normal saline over the counter ounce after after meals (post cibum) Physician's Dest Reference hydrogen ion concentration (acidity and alkalinity measurement) orally (per os) parts per million per rectum as needed (pro re nata) pint every every twelve hours every four hours every six hours every eight hours every day (Continued) Table 5-3 continued

35 Abbreviation qh qid qn qod or eod qp qt Rx s sid sig sol n or soln SQ, SC, subq, or subc T tab tid tsp vol VPB every hour Meaning four times daily (quarter in die) every night every other day as much as desired quart prescription without once daily (qd or q24h are preferred abbreviations) let it be written as (used when writing prescription) solution subcutaneous tablespoon or tablet (or temperature) tablet three times daily (ter in die) teaspoon volume Veterinary Pharmaceuticals and Biologicals Table 5-3 continued

36 Table 5-4 Basic Information for Records, Prescriptions, and Labels Information Records Prescriptions Labels Name, address, and telephone number of the veterinarian Name, address, and telephone number of the client + + Name only Identification of the animal(s) treated, species, and numbers of animals treated, when possible Date of treatment, prescribing, or dispensing of drug Name and quantity of the drug to be prescribed or dispensed Dose and duration directions for use Number of refills authorized + + May be included Table 5-4