AMENDMENTS EN United in diversity EN. European Parliament

Transcription

1 European Parliament Committee on Agriculture and Rural Development 2017/2254(INI) AMDMTS Matt Carthy A European One Health Action Plan against Antimicrobial Resistance (AMR) (2017/2254(INI)) AM\ docx PE v01-00 United in diversity

2 AM_Com_NonLegOpinion PE v /74 AM\ docx

3 1 Michel Dantin Paragraph -1 (new) -1. whereas the One Health approach aims to maintain the effectiveness of treatments of infections in humans and animals alike, to stem the emergence and spread of antimicrobial resistance and to enhance the development and availability of new effective antimicrobials in the Union and the rest of the world; Or. fr 2 Michel Dantin Paragraph -1 a (new) -1a. whereas antimicrobial resistance poses a cross-border health threat, but the AMR situation varies greatly from one Member State to another; whereas the Commission must therefore identify and act on areas of high European added value within the scope of the powers of the Member States which are responsible for determining their health policies; Or. fr 3 Michel Dantin AM\ docx 3/74 PE v01-00

4 Paragraph -1 b (new) -1b. whereas the environment can contribute to the emergence and spread of antimicrobial resistance in animals, in particular because of human, animal and manufacturing waste streams; Or. fr 4 Mairead McGuinness Paragraph 1 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; points out that ongoing surveillance is essential to understand both the development and dissemination of AMR; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; highlights that tackling AMR is a matter of global responsibility, requiring simultaneous action in human health, animal health and the environment; 5 Ricardo Serrão Santos, Clara Eugenia Aguilera García, Paolo De Castro, Eric Andrieu, Karin Kadenbach, Marc Tarabella, Nicola Caputo, Tibor Szanyi, Nikos Androulakis, Michela Giuffrida, Maria Gabriela Zoană, Maria Noichl PE v /74 AM\ docx

5 Paragraph 1 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires commitment and willingness of the Member States to cooperate within the EU and at the international level and a proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 6 Luke Ming Flanagan Paragraph 1 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health, food production and the environment, as it can serve as a reservoir of antibioticresistance genes; 7 AM\ docx 5/74 PE v01-00

6 Daniel Buda Paragraph 1 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health, the environment and the ability to meet food requirements; Or. ro 8 Beata Gosiewska Paragraph 1 1. Stresses that antimicrobial resistance (AMR) is a critical global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and coordination between human health, animal health and the environment; 1. Stresses that antimicrobial resistance (AMR) is a key global health issue that requires proactive, coordinated action; underlines the importance of taking a holistic approach to tackling AMR through the one-health approach, by ensuring coherence and harmonisation between human health, animal health and the environment; Or. pl 9 Jean-Paul Denanot, Eric Andrieu PE v /74 AM\ docx

7 Paragraph 1 subparagraph 1 (new) Stresses, therefore, the importance of having harmonised data on the use of antimicrobials in the livestock sector; Or. fr 10 Paul Brannen Paragraph 1 a (new) 1a. Recalls the recent Guidelines 1a of WHO on use of medically important antimicrobials in food-producing animals recommending farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals to avoid the spread of antimicrobial resistance and proposing that the use of the last-resort antibiotics be banned altogether in animals; 1a WHO guidelines on use of medically important antimicrobials in foodproducing animals, ISBN : Ricardo Serrão Santos, Paolo De Castro, Clara Eugenia Aguilera García, Karin Kadenbach, Marc Tarabella, Nicola Caputo, Tibor Szanyi, Eric Andrieu, Nikos Androulakis, Maria Gabriela Zoană, Michela Giuffrida, Maria Noichl Paragraph 1 a (new) AM\ docx 7/74 PE v01-00

8 1a. Calls upon the Commission to support Member States in the development, assessment and implementation of national action plans against AMR, namely in what regards monitoring and surveillance systems and adequate support and incentive, taking into account the differences in reality among Member States; 12 Paul Brannen Paragraph 1 b (new) 1b. Underlines that routine use of some of the strongest antibiotics is now a common practice in farming in some developing countries; 13 Paul Brannen Paragraph 1 c (new) 1c. Considers that our understanding on spread of antimicrobial resistance from animals in farms to humans is already quite solid and this is not well recognized in the Action Plan. The fact that this (AP) merely calls for further investigation and for closing knowledge PE v /74 AM\ docx

9 gaps in the matter might just postpone a much needed action; 14 Ulrike Müller, Hilde Vautmans Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; Stresses that Member States' Action Plans must address animal husbandry comprehensively to fulfil the targets of the One Health approach; 15 Miguel Viegas Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans, with measurable (clearly defined quantitative or qualitative) targets, benchmarks and effective measures to achieve their Action Plan targets, are effectively implemented and that the strictly monitored results have been achieved; AM\ docx 9/74 PE v01-00

10 Or. pt 16 Jean-Paul Denanot, Eric Andrieu Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach, taking into account the significant differences in antimicrobial resistance between regions, to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; Or. fr 17 Ricardo Serrão Santos, Clara Eugenia Aguilera García, Paolo De Castro, Karin Kadenbach, Tibor Szanyi, Marc Tarabella, Eric Andrieu, Nikos Androulakis, Maria Gabriela Zoană, Michela Giuffrida, Maria Noichl, Nicola Caputo Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the Action Plans, containing measurable (clearly defined quantitative or qualitative) goals, benchmarks and effective measures to achieve these goals, are effectively implemented, and that results strictly monitored have been achieved; PE v /74 AM\ docx

11 18 Luke Ming Flanagan Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved in a coordinated manner across the EU to ensure their effectiveness, and to strictly monitor the results that have been achieved; 19 Georgios Epitideios Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved in order to arrive at reliable conclusions; Or. el 20 Jan Huitema, Hannu Takkula, Hilde Vautmans, Fredrick Federley Paragraph 2 AM\ docx 11/74 PE v01-00

12 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious and leading approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 21 Mairead McGuinness Paragraph 2 2. Calls on the Commission and the Member States to take an ambitious approach to ensuring that the targets set out in their respective Action Plans are fully and effectively achieved, and to strictly monitor the results that have been achieved; 2. Calls on the Commission and the Member States to take an ambitious approach when setting targets in their respective Action Plans; stresses that targets must be fully and effectively achieved and the results strictly monitored; 22 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 2 a (new) 2a. Calls, in particular, on the Commission to develop rules for harmonised monitoring of veterinary antimicrobials sales and consumption in domesticated animals, obliging Member PE v /74 AM\ docx

13 States to report relevant and comparable data on sales and consumption of antimicrobial veterinary medicines, to the European Medicines Agency (EMA), to allow for cross-country comparisons and identification of best practice at the national level; Considers that there should be regular reviews to check efficacy; 23 Albert Deß, Norbert Lins, Peter Jahr Paragraph 2 a (new) 2a. Stresses that farmers are aware of their particular responsibility for animal protection, animal health and food safety and ensure the proper use of antibiotics, which are necessary to keep animals healthy and treat sick animals as quickly as possible; Or. de 24 Daciana Octavia Sârbu Paragraph 2 a (new) 2a. Stresses that antimicrobial resistance is a multifactorial problem and calls on the Commission and on Member States to foster cooperation between veterinarians, agricultural sector stakeholders and other health AM\ docx 13/74 PE v01-00

14 professional in the fight against antimicrobial resistance; 25 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 2 b (new) 2b. Underlines that, taking into account the scientific advice of EFSA and other relevant Union agencies, one of the targets set out in all Member States' Action Plans should be to reserve Critically Important Antimicrobials, as identified by the WHO, exclusively for human use; 26 Michel Dantin Paragraph 2 a (new) 2a. Calls for better enforcement of EU legislation on surveillance of AMR in food-producing animals and on the use of veterinary medicinal products and medicated feeding stuffs; Or. fr 27 PE v /74 AM\ docx

15 Ulrike Müller, Hilde Vautmans Paragraph 2 a (new) 2a. Calls on the Commission and Member States to distinguish between livestock and pets, particularly in the design of monitoring and assessment of the use of antimicrobials and in the design of measures to address their use; 28 Albert Deß, Norbert Lins, Peter Jahr, Herbert Dorfmann Paragraph 2 b (new) 2b. Notes that antibiotics can only be used in livestock farming following diagnosis and prescription by a veterinarian; Or. de 29 Albert Deß, Norbert Lins, Peter Jahr, Herbert Dorfmann Paragraph 2 c (new) 2c. Stresses that comprehensive monitoring of antibiotics in farming has been developed in conjunction with veterinarians which comprehensively documents the use of antibiotics and further improves their application; regrets AM\ docx 15/74 PE v01-00

16 that there is as yet no comparable system in human medicine; Or. de 30 Mairead McGuinness Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions, including the on-going and inter-related work on the manufacture, placing on the market and use of medicated feed and repealing Council Directive 90/167/EEC and the proposal for a regulation of the European Parliament and of the Council on veterinary medicinal products, must address prophylactic and metaphylactic use of antibiotics; 31 Daniel Buda Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative PE v /74 AM\ docx

17 solutions must address prophylactic and metaphylactic use; solutions must address prophylactic and metaphylactic use; welcomes the tripartite negotiations on the finalization of regulations on veterinary medicines and the placing on the market of medicated feed, necessitating new regulations on the prophylactic use of antibiotics; Or. ro 32 Matt Carthy Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; in this regard notes the progress that has already been made in this direction through negotiations for a Regulation on Veterinary Medicinal Products and the Regulation on Medicated Feed: manufacture, placing on the market and use; 33 Ricardo Serrão Santos, Paolo De Castro, Nicola Caputo, Eric Andrieu, Marc Tarabella, Tibor Szanyi, Maria Gabriela Zoană, Michela Giuffrida Paragraph 3 3. Calls for legislative solutions that 3. Calls for solutions that will assist AM\ docx 17/74 PE v01-00

18 will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; farmers in reducing the need for the use of antibiotics and consequently to reduce their use in livestock farming, reinforcing the obligation for a prudent and responsible use of these veterinary medicinal products; insists that such solutions must address the prophylactic and metaphylactic use and the use in animals of antimicrobials that are of critical importance to human health; 34 Ulrike Müller, Hilde Vautmans Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must carefully address prophylactic and metaphylactic use, considering that it sometimes may be required to address a subliminal infection in a herd before a full outbreak occurs; 35 Michel Dantin Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of 3. Calls for proposals for new regulatory solutions (basic legislation, PE v /74 AM\ docx

19 antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; secondary legislation or EU guidelines) with a view to assisting farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; Or. fr 36 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address and implement the phase out of routine prophylactic use of antimicrobials and of metaphylactic use of antimicrobials in groups of animals; 37 Jan Huitema, Pavel Telička, Hannu Takkula, Hilde Vautmans, Fredrick Federley, Ulrike Müller Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of AM\ docx 19/74 PE v01-00

20 antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; endeavours to keep the additional administrative burden as small as possible; 38 Laurenţiu Rebega, Philippe Loiseau, Angelo Ciocca Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of using antimicrobials only where justified (established diagnosis, antimicrobial or antibiotic prescribed by a veterinarian); insists that such legislative solutions must address prophylactic and metaphylactic use; Or. ro 39 Georgios Epitideios Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials, so as to protect the health of animals and humans; insists that such legislative solutions must address prophylactic and metaphylactic use; PE v /74 AM\ docx

21 Or. el 40 James Nicholson Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for solutions based on collaboration between government, industry and the veterinary profession that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such solutions should address prophylactic and metaphylactic use; 41 Philippe Loiseau, Jacques Colombier, Laurenţiu Rebega, Angelo Ciocca Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will assist farmers in adjusting the use of antibiotics in livestock farming, by adopting a pro-active attitude through health observation and information; insists that such legislative solutions must address prophylactic and metaphylactic use; Or. fr 42 Beata Gosiewska AM\ docx 21/74 PE v01-00

22 Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for legislative solutions that will make it easier for farmers to reduce the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; Or. pl 43 Clara Eugenia Aguilera García Paragraph 3 3. Calls for legislative solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; insists that such legislative solutions must address prophylactic and metaphylactic use; 3. Calls for better coordination between state and regional health agencies in order to identify solutions that will assist farmers in reducing the use of antibiotics in livestock farming, with the aim of prudent and responsible use of antimicrobials; Or. es 44 Karin Kadenbach, Maria Noichl Paragraph 3 a (new) 3a. Reminds that food is one of the possible vehicles for transmission of resistant bacteria from animals to human PE v /74 AM\ docx

23 beings and furthermore that drugresistant bacteria can circulate in populations of human beings and animals, through water and the environment such as the risks for infection with resistant organisms by contaminated crops treated with antimicrobial agents or by manure, and farmyard run-offs into groundwater. Points out that in this context the spread is influenced by trade, travel and both human and animal migration; 45 Nicola Caputo, Marc Tarabella, Ricardo Serrão Santos, Momchil Nekov Paragraph 3 a (new) 3a. Believes that, in order to facilitate responsible use of antimicrobials, there is an imperative need for rapid, reliable and efficacious veterinary diagnostics both to identify the cause of disease and to perform antibiotic sensitivity testing; is of the opinion that this would facilitate correct diagnosis, allow for a targeted use of antimicrobials, support using as little as possible critically important antimicrobials and, therefore, inhibit the development of antimicrobial resistance; 46 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 3 a (new) AM\ docx 23/74 PE v01-00

24 3a. Supports, as a minimum, the Council's response to the draft Codex Alimentarius Code of Practice to Minimise and Contain Antimicrobial Resistance, and its principles 18 and 19 on responsible and prudent use of antimicrobials; 47 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 3 b (new) 3b. Stresses that responsible and prudent prophylactic use of antimicrobials should be limited to exceptional cases. This use should not be systematic, nor routine, nor applied to compensate for poor hygiene or inadequate animal husbandry practices, and it should be prescribed by a veterinarian only for a limited duration to cover the period of risk. It should always be based on epidemiological and clinical knowledge, with documented justification. Prophylactic use of antibiotics should be limited to individual animals only. Prophylactic use should always represent a very small proportion of total therapeutic infectious disease-related use. 48 Nicola Caputo, Marc Tarabella, Momchil Nekov PE v /74 AM\ docx

25 Paragraph 3 b (new) 3b. Believes that the fight against antibiotic resistance should start on farms; is of the opinion that the EU should prohibit the purely preventive use of antibiotics, restrict collective treatment to very specific cases, prohibit the veterinary use of antibiotics that are critically important for human medicine and put an end to online sales of antibiotics, vaccines and psychotropic substances; takes the view that, thanks to these measures, the amounts of antibiotics found on consumers plates will be reduced; 49 Karin Kadenbach, Maria Noichl Paragraph 3 b (new) 3b. Reminds that poor quality of medical and veterinary products with low concentrations of active ingredients and/or in conjunction with long-term use, encourage emergence of resistant microbes; calls therefore on the Commission and MS to improve/design laws that ensure that medicines are of assured quality, safe and effective and that their use will follow strict principles; AM\ docx 25/74 PE v01-00

26 50 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 3 c (new) 3c. Stresses that responsible and prudent metaphylactic use should not be systematic, nor routine, nor applied to compensate for poor hygiene or inadequate animal husbandry practices. The decision to administer antimicrobials metaphylactically should be based on a diagnosis and prescribed by a veterinarian, with documented justification; The decision should be based on epidemiological and clinical knowledge, an understanding of risk factors associated with the group, and in accordance with pre-established criteria for initiation of administration of antimicrobials. When considering preventative use in populations, it should be focused on subsets at highest risk. When antimicrobials are used for (nonroutine) metaphylaxis, owners and keepers of food-producing animals shall ensure that they have a health plan specifying appropriate non-medical measures to reduce the need to resort to metaphylactic use in the future; 51 Eric Andrieu, Jean-Paul Denanot Paragraph 4 4. Calls for further research and 4. Calls for further research and PE v /74 AM\ docx

27 development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; development into new antimicrobials or new alternative products to strengthen natural defences at an early stage and during critical farming phases; Encourages also research into and the development of the use of bio-control solutions and products derived from natural substances (in particular algae), including the development of more sustainable farming systems based on less intensive farming models; Or. fr 52 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; recalls that stress suppresses certain immune functions against disease, and that research shows that animals in less intensive farming models experience less stress, meaning their immune systems are less compromised as a result; 53 Ricardo Serrão Santos, Paolo De Castro, Nicola Caputo, Karin Kadenbach, Tibor Szanyi, Marc Tarabella, Eric Andrieu, Nikos Androulakis, Maria Gabriela Zoană, Michela Giuffrida, Maria Noichl AM\ docx 27/74 PE v01-00

28 Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models, underlying the need for incentives for EU and global coordination and cooperation on research programmes in order to stimulate the development of new antimicrobials, alternative therapies and (rapid) diagnostics; 54 Mairead McGuinness Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for increased investment to conduct further research and development into new antimicrobials and encourages alternatives, in particular cost-effective alternatives, to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 55 Michel Dantin Paragraph 4 PE v /74 AM\ docx

29 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages preventive solutions or alternatives to be investigated, including the development of new and effective preventive vaccines for animals and more sustainable farming systems based on less intensive farming models; Or. fr 56 Annie Schreijer-Pierik Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated; Or. nl 57 Maria Lidia Senra Rodríguez Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages the incentivising of research into natural and holistic veterinary medicine, including the development of more sustainable farming systems based on AM\ docx 29/74 PE v01-00

30 less intensive farming models and, above all, on agroecology; Or. es 58 Jan Huitema, Ulrike Müller, Pavel Telička, Hilde Vautmans, Fredrick Federley Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives, such as vaccines, to be investigated, including the development of more sustainable and animal friendly farming models to ensure adequate animal husbandry; 59 Clara Eugenia Aguilera García Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems which preserve the competitiveness of those systems; Or. es 60 PE v /74 AM\ docx

31 James Nicholson Paragraph 4 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on less intensive farming models; 4. Calls for further research and development into new antimicrobials and encourages alternatives to be investigated, including the development of more sustainable farming systems based on sustainable intensification; 61 Luke Ming Flanagan Paragraph 4 a (new) 4a. Firmly believes that the most effective means of combatting AMR which is linked to the intensification of farming is the promotion of short supply chains in the food industry and the creation of local quality brands, these can bring benefits such as; Improved negotiating positions for farmers; These supply chains offer farmers greater power during negotiations, especially during those with retailers, Increased communication between producer and consumer; Short supply chains can lead to job creation, especially in rural areas, Reduced transportation costs; Short supply chains typically serve a local area, reducing the energy costs, transportation costs, and CO2 emissions, Increased transparency; AM\ docx 31/74 PE v01-00

32 It s easier to make short supply chains with few or no intermediaries transparent than it is longer and more complex ones, Reduced risk; A short supply chain reduces the risk of damage, contamination, Increased quality; Doing business and transporting goods locally increases their overall quality by reducing the need for freezing and use of preservatives, Greater profits; Short supply chains offer farmers with greater profits while keeping the end-price more or less the same for consumers; 62 Philippe Loiseau, Jacques Colombier, Laurenţiu Rebega Paragraph 4 a (new) 4a. Calls for approaches to antimicrobials to take into account the need for a paradigm shift in farming; calls also for flanking measures to help the agricultural sectors manage the transition from an intensive feedlots - type model to a more extensive type of farming, based on space and grassland (in France, for example, each cow has an average of one hectare to feed and recycle its excrement); Or. fr 63 Thomas Waitz on behalf of the Verts/ALE Group PE v /74 AM\ docx

33 Paragraph 4 a (new) 4a. Highlights that the spread of antimicrobials and consequent antimicrobial resistance in the environment is also a growing concern, requiring further research; Stresses in particular the urgent need for in-depth research on the impact of antimicrobial substances in food crops and animal feed on microbial communities in soil and aquatic ecosystems, as well as the disposal of slurry and wastewater; 64 Nicola Caputo, Marc Tarabella, Jean-Paul Denanot, Momchil Nekov Paragraph 4 a (new) 4a. Believes that, in order to encourage research into new antimicrobials, incentives are needed, including longer periods of protection for technical documentation on new medicines, commercial protection of innovative active substances, and protection for significant investments in data generated to improve an existing antimicrobial product or to keep it on the market; 65 Jean-Paul Denanot, Eric Andrieu AM\ docx 33/74 PE v01-00

34 Paragraph 4 a (new) 4a. Stresses, therefore, that the current innovation framework does not effectively encourage R&D into AMR and calls for the adjustment and harmonisation of the intellectual property regime at European level, in particular in order to better match protection with the period requested for the innovative medicine in question; Or. fr 66 Albert Deß, Norbert Lins, Peter Jahr, Herbert Dorfmann Paragraph 4 a (new) 4a. Calls for a reduction in the use of antibiotics, particularly last-line antibiotics, to be the objective not only in livestock farming but across the whole of veterinary and human medicine; Or. de 67 Paul Brannen Paragraph 4 a (new) 4a. Calls for further research on the link between exposure to commercial formulations of pesticides and developed PE v /74 AM\ docx

35 antimicrobial resistance; 68 Mairead McGuinness Paragraph 4 a (new) 4a. Highlights the role that farm advisory services can play in promoting sustainable farm management practices; 69 Nicola Caputo, Marc Tarabella, Jean-Paul Denanot, Momchil Nekov Paragraph 4 b (new) 4b. Highlights that significant volumes of antibiotics are used either prophylactically amongst healthy animals, to stop the development of an infection within a flock or herd, or simply for growth promotion, to speed up the pace at which animals gain weight; notes that both uses are particularly prevalent in intensive agriculture, where animals are kept in confined conditions; considers it necessary to take measures to encourage extensive grazing or organic farming methods; AM\ docx 35/74 PE v01-00

36 70 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 4 b (new) 4b. Stresses the importance of effective environmental risk assessment in the approvals process for new and existing veterinary medicines with antimicrobial properties, particularly as concerns the end-points of antimicrobial substances in the wider environment; 71 Mairead McGuinness Paragraph 4 b (new) 4b. Points out that in light of the reduced effectiveness of certain antibiotics, rapid diagnostic tests can assist health professionals to provide targeted and effective treatment options as a viable alternative to antibiotic use in humans; 72 Nicola Caputo, Marc Tarabella, Momchil Nekov Paragraph 4 c (new) PE v /74 AM\ docx

37 4c. Believes that requirements to ensure that labelling makes reference to antibiotic use would improve consumer knowledge and help enable consumers to make a more informed choice; notes that having products labelled as "antibioticfree" might also provide incentives for farmers to withhold antibiotic treatment when an animal might need it, for fear of the economic cost of not being able to sell the meat; 73 Mairead McGuinness Paragraph 4 c (new) 4c. Underlines the importance of a long term sustainable budget for research and development into both new antimicrobials and alternatives to antibiotics; 74 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 4 c (new) 4c. Notes that some plant protection products also have antimicrobial properties, which may affect the spread of antimicrobial resistance; AM\ docx 37/74 PE v01-00

38 75 Miguel Viegas Paragraph 5 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 5. Stresses that the prevention and control of infections in humans and animals and therefore disease prevention must be the first step in tackling the legislation, in the veterinary field, providing for best practices to be used in welfare, hygiene and proper management, effective biosecurity measures and the use of alternative therapies and diagnostic resources, with a view to reducing pressure from infections and, therefore, the need to use antibiotics; emphasises that prescription, a status only for antibiotics, accountability of professionals in a number of sectors and cooperation between veterinarians and animal owners are key factors for success; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; Or. pt 76 Ricardo Serrão Santos, Clara Eugenia Aguilera García, Paolo De Castro, Nicola Caputo, Eric Andrieu, Karin Kadenbach, Marc Tarabella, Tibor Szanyi, Nikos Androulakis, Maria Gabriela Zoană, Michela Giuffrida, Maria Noichl Paragraph 5 5. Stresses that disease prevention must be the first step for legislation 5. Stresses that the prevention and control of infections in animals are key to PE v /74 AM\ docx

39 tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; tackling AMR in agriculture and therefore disease prevention must be the first step for legislation tackling, via ensuring a high standard of animal welfare, among others, and thus reducing the need to resort to antibiotics; emphasises that the prescription-only status for antibiotics and the accountability of professionals in the various sectors, as well as the cooperation between the veterinarian and the livestock farmers, are key factors for success; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 77 Georgios Epitideios Paragraph 5 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry but only in combination with other methods of protecting animal health; Or. el 78 James Nicholson Paragraph 5 AM\ docx 39/74 PE v01-00

40 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 5. Stresses that disease prevention must be the first step for proposals to tackle AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry and that good bio-security has a role to play; 79 Jan Huitema, Pavel Telička, Hannu Takkula, Hilde Vautmans, Fredrick Federley Paragraph 5 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; believes that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 5. Stresses that disease prevention must be the first step for legislation tackling AMR in agriculture, both to ensure a high standard of animal welfare and reduce the need to resort to antibiotics; demands that antibiotics should never be used as compensation for poor hygiene or inadequate animal husbandry; 80 Thomas Waitz on behalf of the Verts/ALE Group Paragraph 5 a (new) 5a. Recalls the preventative measures to be used before resorting to PE v /74 AM\ docx

41 antimicrobial treatment of entire groups (metaphylaxis) of food-producing animals: using good healthy breeding stock that grows naturally, with suitable genetic diversity, conditions that respect the behavioural needs of the species, including social interactions and hierarchies, stocking densities that do not increase risk of disease transmission, isolation of sick animals away from the rest of the group, (for chickens and smaller animals) subdivision of flocks into smaller, physically separated groups, implementation of existing rules on animal welfare already in cross compliance as set out in SMRs 11, 12, 13 of Annex II to Reg. 1306/2013 1a 1a Reg. 1306/2013 on the financing, management and monitoring of the CAP (OJ L 347, , p.549), applying rules laid out in Dir. 98/58/EC on protection of animals kept for farming purposes (OJ L 221, , p. 23); Dir. 91/630/EEC laying down minimum standards for the protection of pigs (OJ L 340, , p. 33); Dir. 91/629/EEC laying down minimum standards for the protection of calves (OJ L 340, , p. 28) 81 Paul Brannen Paragraph 5 a (new) AM\ docx 41/74 PE v01-00

42 5a. Stresses that studies suggest 1a that exposure to herbicides and their commercial formulations at concentrations comparable to those associated with typical application rates in agricultural fields can develop tolerance to antibiotics in offending bacteria; 1a Kurenbach at al., 2015: Sublethal exposure to Commercial Formulations of the Herbicides Dicamba,2,4- Dichlorophenoxyacetic Acid, and Glyphosate Cause Changes in Antibiotic Susceptibility in Escherichia coli and Salmonella enterica 82 Karin Kadenbach, Maria Noichl Paragraph 5 a (new) 5a. Highlights the value of vaccines in combating AMR; recommends integration of targets for life-long vaccination as element of veterinary national action plans on AMR; 83 Paul Brannen Paragraph 5 b (new) PE v /74 AM\ docx

43 5b. Recognizes that herbicides are routinely tested for toxicity but not for sublethal effects on microbes and stresses, for the reasons above, the relevance of consideration of conducting these tests routinely; 84 Karin Kadenbach, Maria Noichl Paragraph 5 b (new) 5b. Welcomes the initiative of several MS to ban of the use of last resort antibiotics, normally used for human treatments, in farm animals; 85 Paul Brannen Paragraph 5 c (new) 5c. Proposes that any authorisation of a herbicide-resistant genetically modified crop (supposedly treated with herbicide to which it is tolerant) take fully into account precautionary principle with respect to indication of the existing link between use of herbicides and antimicrobial resistance and that for any there be a conclusive scientific evidence that such risk can be excluded; AM\ docx 43/74 PE v01-00

44 86 Daniel Buda Paragraph 6 6. Calls on the Commission and the Member States to ensure adequate funding for on-farm investments, such as in quality housing, ventilation, cleaning, disinfection, vaccination and bio-security; 6. Calls on the Commission and the Member States to ensure adequate funding for on-farm investments, such as in spacious quality housing suitable for stockbreeding, ventilation, cleaning, disinfection, vaccination and bio-security; Or. ro 87 Jan Huitema, Ulrike Müller, Pavel Telička, Fredrick Federley, Hilde Vautmans, Hannu Takkula Paragraph 6 6. Calls on the Commission and the Member States to ensure adequate funding for on-farm investments, such as in quality housing, ventilation, cleaning, disinfection, vaccination and bio-security; Believes that on-farm investments such as in quality housing, ventilation, cleaning, disinfection, vaccination, probiotics, prebiotics, genselection and bio-security must be encouraged and should not be undermined in the future CAP; 88 Luke Ming Flanagan Paragraph 6 PE v /74 AM\ docx