Veterinary. Select. Product catalog. animal Safety division First edition VETERINARY SELECT VETERINARY SELECT

Transcription

1 Veterinary Select Product catalog animal Safety division First edition VETERINARY SELECT VETERINARY SELECT

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3 Sally CONTENTS Biologics...3 Supplements, Medications and Antibiotics...6 Injectables Wound Care Additional Product Index Ordering Information To order, call 800/ (USA/Canada) 1

4 Neogen Corporate Profile Neogen Corporation develops, manufactures, and markets animal and food safety solutions. Neogen (NASDAQ: NEOG), founded in 1982, has grown to over 850 employees in multiple U.S. and international locations. Neogen has been repeatedly named one of Forbes Magazine s best small companies in America, and is in NASDAQ s top tier of companies its Global Select Market. For more about Neogen, please visit Animal Safety Neogen s Lexington, Ky.-based Animal Safety Division manufactures and markets veterinary pharmaceuticals, vaccines, topicals, diagnostic tests, instruments, rodenticides, insecticides, disinfectants, and genomic solutions. Neogen s products include: Veterinary Performance and Companion Animal Products. Neogen s biological line includes BotVax B, the only USDA-approved vaccine against equine botulism type B; EqStim, an effective USDA-approved immunostimulant for adjunctive treatment of equine respiratory disease complex; and Uniprim, a popular veterinary antibiotic. Veterinary Instruments and Supplies. Neogen offers affordable precision veterinary instruments and supplies, including such recognized brand names as Ideal Instruments, SyrVet, Prima Tech, and Ag- Tek. Neogen s extensive line of durable and disposable instruments is convenient and dependable. We offer products from needles and syringes, to breeding and delivery. Livestock and Canine Genomics. Neogen s GeneSeek and Igenity subsidiaries are leading global providers of DNA testing and bioinformatics for animal agribusiness and veterinary medicine. With complementary applications, GeneSeek and Igenity provide everything from research and development to final implementation of molecular solutions for applications such as genetic improvement, disease management and identity management. Diagnostic Products. Neogen s tests detect more than 90 different drugs that may be considered drugs of abuse in racing and eventing animals, and residues in food animals. Rodenticides. Neogen s proven rodenticides are used for control of rodents and complement its disinfectants as a critical component of an overall biosecurity program. Rodents compromise the quantity and quality of food and feed, and spread disease. Insecticides. Neogen s newly acquired Chem-Tech products include well-known and proven environmentally friendly insecticides that have a range of applications in the food and animal safety industries. Disinfectants and Cleaning Products. Animal facilities, from companion animal veterinary clinics to production livestock operations, benefit from Neogen s diverse range of cleaners and disinfectants. Neogen also offers step-by-step procedures to clean then disinfect numerous surface types of organic matter, biofilms and serum content. These products have broad germicidal capabilities to remove infectious agents, such as avian influenza. 2 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

5 Biologics To order, call 800/ (USA/Canada) 3

6 BotVax B Clostridium botulinum Type B Toxoid For the prevention of equine botulism Type B due to Clostridium botulinum in healthy horses. Clostridium botulinum Type B Accounts for more than 85% of equine botulism cases. 1 Strikes foals and adult horses; is usually rapidly fatal. Its spores remain viable in soil for years. BotVax B, your best defense against equine botulism Type B. Prevention is your best defense! Horses are extremely sensitive to botulinum toxins the world s most potent toxins. Timely treatment is critical due to botulism s rapid and severe progression. Vaccination is far less expensive than treatment, which can exceed $10,000 with no guarantee of survival. Risk factors Any baled hay (round, square, big or small), haylage or silage products. Horses and foals that reside in or travel to endemic areas. Horses that travel for shows, races, and other equine events. Horses that may sustain a wound, including injection site abscesses, umbilical infections, puncture wounds, and castration sites. BotVax B provides simple, safe protection against Type B equine botulism 2 The only USDA-approved vaccine for equine botulism. Sold exclusively to licensed veterinarians since Made in the U.S.A. Safe to administer to healthy adult horses, pregnant mares, and foals two weeks of age and older. Three-dose initial series, with single annual booster thereafter. Protects against all modes of equine botulism type B: Forage poisoning Shaker Foal Syndrome (Toxicoinfectious Botulism) Wound botulism Included in the American Association of Equine Practitioners Vaccination Guidelines 3. Item No. BotVax B ml Vial (5 doses per vial) ml Vial (1 dose per vial) Directions for use Shake well before use. Inject 2 ml intramuscularly, using aseptic technique, at monthly intervals for a total of 3 doses. Booster annually with a single 2 ml intramuscular dose. Research has demonstrated that pregnant mares immunized during the third trimester of gestation, with the third dose (booster) given 2-4 weeks before parturition, respond with antibody. This antibody is concentrated in colostrum and results in significant passively acquired antibody/immunity. A consumer brochure on equine botulism is available For more information, contact Neogen at 800/ or 859/ , or via at equinebotulism@neogen.com, or visit 1 Horses are also susceptible to Clostridium botulinum Types A, C and potentially D. 2 BotVax B does not confer protection against other Clostridium botulinum toxin types Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

7 EqStim Propionibacterium acnes (0.4 mg/ml nonviable P. acnes suspended in 12.5% ethanol in saline) A USDA-approved immunostimulant for adjunctive treatment of equine respiratory disease complex (ERDC). Why use EqStim? EqStim has been demonstrated to be effective in increasing the rate of recovery when used in conjunction with antibiotic or hyperimmune therapy in the treatment of primary and secondary bacterial and viral infections associated with equine respiratory disease complex. Proven to provide rapid recovery from bacterial and viral respiratory infections. Employs no adjuvants safe for adult horses, ponies, and foals. Evaluated in mares diagnosed with persistent endometritis. Results of this randomized, double-blinded clinical trial were published in the July 1, 2007 issue of JAVMA. 1 Made in the U.S.A Directions for use Administer by the intravenous route. Shake well to obtain uniform suspension. Foals: 1 ml Older Horses: 1 ml per 250 lbs of body weight. Repeat at day 3 (or at day 4) and at day 7, and weekly thereafter as needed. 1 Contact Neogen for a complimentary reprint of this article: Rohrbach, Barton W., VMD, MPH, DACVPM; Peter C. Sheerin, DVM, DACT; Charles K. Cantrell, DVM; Phillip M. Matthews, DVM; John V. Steiner, DVM, DACT; Lewis E. Dodds, DVM. Effect of adjunctive treatment with intravenously administered Propionibacterium acnes on reproductive performance in mares with persistent endometritis. JAVMA July 1, 2007; 231(1): ImmunoRegulin Propionibacterium acnes Macie A USDA-approved immunostimulant for controlling and reducing the lesions of chronic recurrent pyoderma in the dog. Why use ImmunoRegulin? It s an extremely stable product that requires only room temperature storage and doesn t contain albumins. Has been used safely in millions of animals, and does not have a high potential for causing anaphylaxis. With ImmunoRegulin therapy, less dosage and less frequency of antibiotic treatment are usually required. Clinical trials demonstrated an 80% rate of healing when ImmunoRegulin was used in conjunction with antibiotics. Made in the U.S.A Directions for use Two IV injections per week for 2 weeks. One IV injection per week until definite improvement is noted. One injection per month to avoid relapse and to maintain clinical improvement. Item No. ImmunoRegulin ml Vial Item No. EqStim ml Vial ml Vial To order, call 800/ (USA/Canada) inform@neogen.com 5

8 Supplements, Medications and Antibiotics Wrangler Tiny Bugs 6 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

9 PanaKare Plus Pancreatic Enzyme Concentrate Plus Fat Soluble Vitamins For use as a digestive aid in replacement therapy in dogs and cats where digestion of protein, carbohydrates, and fat is inadequate due to exocrine pancreatic insufficiency (EPI). Each tablet contains a minimum of: Lipase... 9,000 USP units Protease... 57,000 USP units Amylase...64,000 units Each 2.8 g (1 teaspoon) of powder contains a minimum of: Lipase... 71,400 USP units Protease ,000 USP units Amylase...460,000 units Why choose PanaKare? Vitamin Therapy Serum concentrations of fat soluble vitamins A, D 3, and E are often abnormal in dogs and cats with EPI and do not usually increase in response to treatment. While ideal dosage levels have not been officially established, oral supplementation with fat soluble vitamins is widely accepted. PanaKare is made in the U.S.A. Item No. PanaKare Plus Tablets mg, 100 Tablets mg, 500 Tablets Item No. PanaKare Plus Powder oz Powder oz Powder oz Powder Powder: Administer before each meal and estimate dosage according to severity of the condition and weight of the animal. The powder is added to moistened food (canned or dry). Thorough mixing is necessary to bring the enzymes into close contact with the food particles. After mixing, incubate at room temperature for minutes. Average dose/meal Dogs: ¾ 1 teaspoon (2.8 g / teaspoon) Cats: ¼ ¾ teaspoon Tablets: Administer before each meal and estimate dosage according to severity of the condition and weight of the animal. Average dose/meal Dogs: 2 3 tablets Cats: ½ 1 tablet Millie Archie To order, call 800/ (USA/Canada) inform@neogen.com 7

10 Trust is earned. Neogen s wide range of proven products has earned the continued use and trust of animal caregivers worldwide. Roscoe RenaKare Potassium Gluconate USP Potassium supplement for use in potassium deficient states in dogs and cats. Each 2.34 g (½ teaspoon) of gel contains a minimum of: Potassium Gluconate... 2 meq (468 mg) in a palatable base Each 0.65 g (¼ teaspoon) of powder contains a minimum of: Potassium Gluconate... 2 meq (468 mg) in a palatable base Each tablet contains a minimum of: Potassium Gluconate... 2 meq (468 mg) Why choose RenaKare? It helps correct potassium deficiencies Potassium depletion is relatively common among dogs, and especially cats. The major mechanisms of potassium depletion include excessive urinary potassium losses, gastrointestinal losses, and decreased dietary intake. Potassium supplementation can prevent or treat potassium deficits, and when indicated, oral therapy is generally considered safe and easy to administer. RenaKare is made in the U.S.A. The recommended dosage for adult cats and dogs is: Tablets: 1 tablet per 10 lbs of body weight, twice daily Powder: 1/4 teaspoon per 10 lbs of body weight, twice daily Gel: 1/2 teaspoon per 10 lbs of body weight, twice daily Item No. RenaKare Tablets mg, 100 Tablets Item No. RenaKare Gel oz Tube (Vanilla Custard Flavor) Item No. RenaKare Powder oz Bottle 8 Neogen Corporation 944 Nandino Blvd. Lexington, KY Dixxi

11 ThyroKare Tablets Levothyroxine Sodium Tablets Provides thyroid hormone replacement therapy in all conditions of inadequate production of thyroid hormones in dogs. Each tablet contains the active ingredient: Levothyroxine Sodium, USP mg (in 0.1 mg increments) Why choose ThyroKare tablets? Formulation minimizes product degradation Thyroid hormones, including levothyroxine sodium (T4), share the challenge of maintaining potency throughout stated shelf life. Product potency is decreased by moisture, light, heat, and carbohydrates (e.g., lactose, sucrose, dextrose, and starch) commonly used as filler. Therefore, it is important to exclude the use of fillers to enhance the stability of T4 tablets. Neogen s formulation minimizes product degradation. Other factors such as particle size, granulation process, disintegrate selection, selection of active ingredient synthesis and source, excipients, and other proprietary data are used to provide a T4 product that offers optimum stability and reliability. ThyroKare is made in the U.S.A. The initial recommended daily dose is 0.1 mg per 10 lbs of body weight twice daily. Dosage is then adjusted according to patient s response by monitoring T4 blood levels every four weeks. The usual maintenance dose is 0.1 mg per 10 lbs once daily. Tablets may be administered orally or placed in food. Item No. ThyroKare Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets Item No. ThyroKare Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets mg, 180 Tablets mg, 1,000 Tablets Chloe To order, call 800/ (USA/Canada) inform@neogen.com 9

12 ThyroKare Powder Levothyroxine Sodium Powder For use in horses to correct conditions associated with low circulating thyroid hormone (hypothyroidism). Levothyroxine sodium (T4) is a synthetic isomer of thyroxine. Each pound (453.6 g) contains: Levothyroxine Sodium USP % (1.0 g) One level teaspoon contains approximately 12 mg of T4 and one level tablespoon contains approximately 36 mg of T4. Why choose ThyroKare powder? Highly palatable powder Sprinkles easily onto food The suggested initial dose is 0.5 to 3.0 mg of T4 per 100 lbs of body weight (1 to 6 mg/100 kg) once per day or in divided doses. The recommended daily dose is ½ to 2½ level teaspoons for a 500 kg (1,100 lb) horse. Item No. ThyroKare Powder lb lb Aspirin USP with Apple Flavoring 99.9% Pure Acetylsalicylic Acid USP in Powder Form For use to effectively treat a wide variety of minor muscular or joint pains, and to relieve fever. Aspirin, the original nonsteroidal anti-inflammatory drug (NSAID), is a pure analgesic (pain reliever/ reducer) and antipyretic (antifever) medication. Horses absorb aspirin well from the gastrointestinal tract. Each pound contains: Acetylsalicylic Acid (Aspirin) g Sucrose... q.s. Apple Flavor... q.s. Administer orally; ½ oz contains approximately 7 g of aspirin. Cattle, Horses (adult): g ( 1 /2-4 oz) Calves, Foals: 6 12 g ( 1 /4-1 /2 oz) Dogs: g ( 1 /280-1 /14 oz) Sheep, Swine: 2 7 g ( 1 /14-1 /4 oz) Poultry: 0.30% level in ration Item No. Aspirin USP lb* with Apple Flavor *This is a 99.9% Aspirin USP powder blended with apple-flavored sucrose (sugar) to improve palatability. 10 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

13 Tri-Hist Granules Antihistamine/Decongestant Powder For use in horses when a histamine antagonizing preparation is required. Treats skin and respiratory allergies such as: Congestion, hives (urticaria), runny nose, itching Each ounce contains: Pyrilamine Maleate USP mg Pseudoephedrine Hydrochloride mg Cornmeal... q.s. ½ ounce (1 level tablespoon) per 1,000 lbs of body weight in feed or via dose syringe. Can be mixed with feed and repeated at 12-hour intervals or as directed by a veterinarian. Item No. Tri-Hist Granules oz DEA List 1 chemical Organic Iodide Powder For animals in iodine depleted zones. Organic Iodide Powder is a palatable sugarbased iodine supplement. Each lb (454 g) contains: Ethylenediamine Dihydroiodide g (Equivalent to 1.3 g per oz) Sucrose... q.s. Add to (protein, grain, or salt mix) in proportions to provide 10 mg per head per day. Protein Mix: Add ½ lb per ton of protein mix and feed at a rate of not more than 2 lbs of mix per head per day. Grain Mix: Add 1 oz per ton of grain and feed at a rate of not more than 16 lbs of mix per head per day. Salt Mix: Add 1 lb per 130 lbs of feeding salt and feed 1 oz per head per day. Do not administer to pregnant, lactating or nursing animals, including dairy cattle in production. Item No. Organic Iodide Powder lb ThyroKare Powder, Aspirin, Tri-Hist and Organic Iodide Powder are made in the U.S.A. To order, call 800/ (USA/Canada) inform@neogen.com 11

14 UNIPRIM TRIMETHOPRIM/SULFADIAZINE For use against a wide range of bacterial infections in horses. UNIPRIM Powder is a combination of trimethoprim and sulfadiazine in the ratio of 1 part to 5 parts by weight, which provides effective antibacterial activity. UNIPRIM Powder contains 67 mg trimethoprim and 333 mg sulfadizine per gram. Label Respiratory tract infections Wounds and abscesses Acute strangles Acute urogenital infections Why choose UNIPRIM? FDA approved, fast-acting, powerful antibiotic. Convenient, ready-to-use, once-daily dosing. Dosing is easy, customizable and accurate. Choice of 2 flavors (apple and non-flavored) and 6 sizes. Extremely palatable. Made in the USA. One packet or two scoops treat a 1,100 lb horse. Adjusted dose is 1 tsp per 100 lbs. Administer once daily for 5 to 7 days. May be used alone or in conjunction with intravenous dosing. Water should be readily available during treatment. Item No. UNIPRIM Powder UP g, Jar AUP g, Jar, Apple Flavor UP g, Jar AUP g, Jar, Apple Flavor UP g, Jar AUP g, Jar, Apple Flavor UP g, Pail AUP g, Pail, Apple Flavor UP g, Packet UP g, Packet ANADA# , Approved by the FDA 12 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

15 Injectables To order, call 800/ (USA/Canada) 13

16 Thiamine Hydrochloride Vitamin B 1, Sterile Solution For use as a supplemental source of thiamine in dogs, cats, and horses. Each ml of sterile solution contains: Thiamine Hydrochloride mg Disodium Edetate % w/v Benzyl Alcohol (preservative)...1.5% v/v Water for Injection...q.s. ph adjusted with hydrochloric acid or sodium hydroxide (IV, IM) Horses, dogs, cats: For intravenous or intramuscular use as determined by veterinarian. Item No. Thiamine Hydrochloride mg, 100 ml Vial NeogenVet Injectables are made in the U.S.A. Vitamin B Complex 150 Sterile Solution For use in the treatment of B-complex vitamin deficiencies in cattle, sheep, and horses. Each ml of sterile solution contains: Thiamine Hydrochloride mg Riboflavin 5 Sodium Phosphate, USP...2 mg Niacinamide mg d-panthenol...10 mg Pyridoxine HCL...10 mg Inositol...20 mg Choline Chloride...20 mg Benzyl Alcohol (preservative)...2% v/v Water for Injection... q.s. (IV, IM, SC) Horses, cattle and sheep: Administer by intramuscular, subcutaneous, or intravenous injection. Dosage may be repeated once or twice weekly as needed. 1 3 ml per 100 lbs of body weight. Item No. Vitamin B Complex ml Vial 14 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

17 Cyanocobalamin 3000 mcg Vitamin B 12, Sterile Solution For use in managing vitamin B 12 deficiencies associated with cobalt deficiency, inadequate intake, or intestinal malabsorption in cattle, horses, sheep, swine, dogs, and cats. (IV, IM, SC) Inject subcutaneously or intramuscularly. May be injected intravenously at the discretion of the veterinarian. Horses and cattle: 0.4 to 0.7 ml Sheep and swine: 0.2 ml Dogs: 0.1 to 0.2 ml Cats: 0.1 ml Item No. Cyanocobalamin 3000 mcg ml Vial Cyanocobalamin 5000 mcg Vitamin B 12, Sterile Solution For use in managing vitamin B 12 deficiencies associated with cobalt deficiency, inadequate intake, or intestinal malabsorption in cattle, horses, sheep, and swine. (IV, IM, SC) Inject subcutaneously or intramuscularly. May be injected intravenously at the discretion of the veterinarian. Horses and cattle: 0.2 to 0.4 ml Sheep and swine: 0.1 ml Dosage may be repeated at weekly intervals if necessary. Item No. Cyanocobalamin 5000 mcg ml Vial Liver 7 Vitamin B Injection, Sterile Solution For treatment and prevention of deficiencies of B vitamins in horses, cattle, sheep, swine, dogs, and cats. Each ml of sterile solution contains: Crude Liver Extract...10 mg Cyanocobalamin mcg Thiamine HCl...10 mg Riboflavin 5 Sodium Phosphate, USP...2 mg Pyridoxine HCl...10 mg Niacinamide...10 mg d-panthenol...10 mg Benzyl Alcohol (preservative)... 2% v/v Water for Injection... q.s. (IV, IM) Horses, cattle, sheep and swine: 1 ml to 2 ml per 100 lbs body weight by intravenous or intramuscular injection. Dogs and cats: 0.1 ml to 0.2 ml per 10 lbs body weight by intravenous or intramuscular injection. Item No. Liver ml Vial To order, call 800/ (USA/Canada) inform@neogen.com 15

18 Phos-Aid Phosphorus, Sterile Solution For parenteral use as a supplemental source of nutritional phosphorus while the ration is being.corrected in areas where feeding rations are inadequate to supply all phosphorus needs for cattle. Each ml of sterile solution contains: Sodium salt of 4-dimethylamino-2-methyl-phenyl phosphinic acid mg Propylene Glycol mg Phenylethanol...6 mg Sodium Sulfite...2 mg Water for Injection...q.s. ph adjusted with sodium carbonate (IV, IM) Injectable phosphorus may be administered by intravenous or deep intramuscular injection. Divide high intramuscular doses between two injection sites. Cattle: 1 ml per 50 to 100 lbs body weight; standard dose range in cattle is 10 ml to 20 ml. Two injections are sufficient if the ration deficiency is immediately corrected. Item No. Phos-Aid ml Vial 16 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

19 Natural E-300 Injectable d-alpha-tocopherol, Sterile Solution For use as an aid in the prevention and treatment of vitamin E deficiencies in swine, cattle, and sheep. Natural E-300 injectable tocopherol (natural-source vitamin E) is a clear, sterile water emulsifiable solution of d-alpha-tocopherol, which is intended as a supplemental source of natural vitamin E. Each ml of sterile solution contains: Vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) IU Benzyl Alcohol (preservative)... 2% v/v (IM, SC) Intramuscular or subcutaneous administration only. May be repeated as needed. If dose is greater than 5 ml, equally divide the dose and inject at two different sites. See chart to the right for dosing information. Item No. Natural E ml Vial Natural E-300 ml SWINE Sows and Gilts 2 weeks pre-partum weeks pre-breeding 4 6 Pigs At birth 1 2 At weaning 2 3 CATTLE (Dairy and Beef) 2 3 weeks pre-partum 8 10 Cows and Heifers At calving 8 10 End of lactation Calves At birth 4 6 At weaning 4 6 Yearlings 5 6 SHEEP Ewes 2 3 weeks pre-partum 4 5 At lambing 4 5 Lambs At birth 2 3 At weaning 2 3 Finishing Lambs 3 4 Natural E-AD Injectable d-alpha-tocopherol with AD, Sterile Solution For use as a supplemental source of vitamins A, D, and E. Natural E-AD injectable d-alpha tocopherol with AD is a clear, sterile water emulsifiable solution of vitamin A, vitamin D 3, and vitamin E. Each ml of sterile solution contains: Vitamin E (as d-alpha-tocopherol, a natural source of vitamin E) IU Vitamin A propionate ,000 IU Vitamin D ,000 IU Benzyl Alcohol (preservative)...2% v/v (IM, SC) Intramuscular or subcutaneous administration only. May be repeated as needed. If dose is greater than 5 ml, equally divide the dose and inject at two different sites. See chart to the right for dosing information. Item No. Natural E-AD ml Vial Natural E-AD ml SWINE Sows and Gilts 2 weeks pre-partum weeks pre-breeding 4 6 Pigs At birth 1 2 At weaning 2 3 CATTLE (Dairy and Beef) 2 3 weeks pre-partum 8 10 Cows and Heifers At calving 8 10 End of lactation 8 10 Calves At birth 4 6 At weaning 4 6 Yearlings 5 6 SHEEP Ewes 2 3 weeks pre-partum 4 5 At lambing 4 5 Lambs At birth 2 3 At weaning 2 3 Finishing Lambs 3 4 To order, call 800/ (USA/Canada) inform@neogen.com 17

20 Sodium Ascorbate Vitamin C, Sterile Solution For use as a nutritive supplement of vitamin C in cattle, horses, sheep, swine, dogs, and cats. Each ml of sterile solution contains: Sodium Ascorbate mg Monothioglycerol...0.5% w/v Edetate Disodium...0.1% w/v Methylparaben (preservative) % w/v Propylparaben (preservative) % w/v (IM) Horses, cattle, sheep, swine, dogs, and cats: Administer intramuscularly 1 to 10 ml, depending on condition, species, and body weight. Repeat daily or as indicated by desired response. Item No. Sodium Ascorbate ml Vial Vita-15 Vitamin-Amino Acid Injection, Sterile Solution For use in horses as a source of nutritional factors. Each ml of sterile solution contains: Pyridoxine HCl mg Riboflavin 5 PO 4 -Na USP mg d-panthenol mg Niacinamide mg Inositol mg Choline Chloride mg Biotin...10 mcg L-Lysine HCl mg Glycine mg Cobalt Gluconate 8 H 2 O... 2 mg Benzyl Alcohol (preservative)...2% v/v Water for Injection...q.s. Sodium Bicarbonate 8.4% Sterile Solution For the treatment of metabolic acidosis. The total osmolar concentration of this product is approximately 2,000 MOsm/L. Each ml of sterile solution contains: Sodium Bicarbonate (equal to 1 meq/ml)...84 mg Water for Injection...q.s. (IV) Inject intravenously. Use caution in emergencies where very rapid infusion of large quantities of bicarbonate is indicated, such as cardiac arrest. Sodium bicarbonate solutions are hypertonic and may produce an undesirable rise in plasma sodium concentration during the process of correction of metabolic acidosis. During cardiac arrest, however, the risks from acidosis exceed those of hypernatremia. In cattle and horses, 200 to 300 ml of 8.4% solution may be given undiluted by rapid infusion using a needle and syringe. Sodium Bicarbonate 8.4% solution is often added to other intravenous fluids for the less urgent forms of metabolic acidosis. The amount of bicarbonate to be given over a 4 to 8 hour period is approximately 2 to 5 meq per kg of body weight (1-2.5 ml/body weight) depending upon the severity of the acidosis as judged by the lowering of total CO 2 content, blood ph, and clinical condition of the animal. Bicarbonate therapy should always be planned in stepwise fashion since the degree of response from a given dose is not precisely predictable. Initially, an infusion of 2 to 5 meq per kg of body weight over a period of 4 to 8 hours will produce a measurable improvement in the abnormal acid-base status of the blood. Completion of therapy is dependent upon the clinical response of the animal. If severe symptoms have abated, the frequency and size of the doses should be reduced. Item No. Sodium Bicarbonate 8.4% ml Vial (IV, IM) Horse: 1 ml per 100 lbs body weight. Repeat once or twice weekly, or as indicated. Item No. Vita ml Vial 18 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

21 Vitamin K 1 Injection Phytonadione, Sterile Solution To treat hypoprothrombinemia induced by ingestion of anticoagulant rodenticides in cattle, horses, swine, sheep, goats, dogs, and cats. It is also used to treat hypoprothrombinemia caused by consumption of bishydroxycoumarin found in spoiled and moldy sweet clover. Each ml of sterile solution contains: Phytonadione...10 mg Emulphor EL mg Dextrose H 2 O mg Benzyl Alcohol (preservative) % v/v Water for Injection...q.s. (IV, IM, SC) Cattle, Calves, Horses, Swine, Sheep, and Goats: Acute hypoprothrombinemia (with hemorrhage) intravenously, mg/kg body weight, at a rate not to exceed 10 mg/minute in mature animals and 5 mg/minute in newborn and very young animals. Nonacute hypoprothrombinemia Intramuscularly or subcutaneously, mg/kg per body weight. Mannitol Injection 20% Diuretic, Sterile Solution For use as an osmotic diuretic in dogs. Mannitol is essentially inert metabolically. When given parenterally, it is freely filtered at the glomerulus which produces osmotic diuresis as more than 90% of the mannitol injected escapes reabsorption. Each 100 ml of sterile solution contains: Mannitol USP...20 g Water for Injection...q.s. This solution contains 1098 mosmols/liter (IV) Dogs: The usual canine dosage administered intravenously is g per kg body weight given over a 30 minute period. This is approximately ml/lb of body weight. Item No. Mannitol Injection 20% ml Vial Dogs and Cats: Acute hypoprothrombinemia (with hemorrhage) and non-acute hypoprothrombinemia mg/kg subcutaneously OR intramuscularly. Use higher end of dose for second generation rodenticides. Item No. Vitamin K ml Vial George Beneli To order, call 800/ (USA/Canada) inform@neogen.com 19

22 Wound Care Buddy 20 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

23 CHONDROPROTEC Polysulfated Glycosaminoglycan, Sterile Solution CHONDROPROTEC is a sterile 10 ml solution containing 1000 mg of polysulfated glycosaminoglycan (100 mg/ml). For use on dogs, cats, and horses. Partial and full Pressure ulcers (Stages I-IV) thickness wounds Surgical incisions Secreting and bleeding Donor sites dermal lesions Venous stasis ulcers 1 st and 2 nd degree burns Directions for use Irrigate wound with normal saline solution. Either pour contents of vial or dispense from syringe to withdraw solution and cover wound site. Cover with a non-adherent dressing such as polyurethane film or Telfa. Note: Subsequent applications can be injected through the dressing as to not disturb the wound bed. Reapply daily and redress wound site every 5 7 days or as needed. Features 1000 mg of PSGAG in a 10 ml vial (100 mg/ml) Derived from bovine trachea Preservative free Patented technology Made in the U.S.A. Item No. CHONDROPROTEC mg, 10 ml Vial Brick HYCOAT Hyaluronate Sodium, Sterile Solution HYCOAT 10 ml is a sterile solution containing 50 mg of sodium hyaluronate (5 mg/ml), having a ph of The average relative molecular weight of HYCOAT 10 ml/50 mg exceeds 1.0 mm daltons. HYCOAT 2 ml is a sterile solution containing 20 mg of sodium hyaluronate 10 mg/ml, having a ph of The average relative molecular weight of HYCOAT 2 ml/20 mg is mm daltons. For use on dogs, cats, and horses. Topical wound management solution. Features Sterile when unopened Synthetically derived Low viscosity and highly consistent Time-tested and safe Preservative free Patented technology Made in the U.S.A. Directions for use Cleanse wound/surgical site Withdraw the HA solution Dispense topically onto the wound site Cover wound area with a non-adherent dressing Change dressing as needed, repeating application of HYCOAT. Item No. HYCOAT mg, 10 ml Vial mg, 2 ml Vial To order, call 800/ (USA/Canada) inform@neogen.com 21

24 Additional Salmonella Testing Salmonella Assay A simple, specific, scalable diagnostic assay for Salmonella detection Highly specific nucleic acid based detection Exhibits no cross-reactivity with other enteric bacteria Microwell format allows flexible handling No amplification steps = faster and easier processing than PCR Why Choose NeogenVet Salmonella Assay: Receive environmental sample testing result in 9 hours Compare with: Typical enrichment method - 48 hours Traditional methods - 72 hours Item No. Salmonella Assay 6700 Salmonella Assay Kit Pyrantel Pamoate Suspension Anthelmintic (dewormer) used for the treatment of pinworms. Each 1 ml contains: Pyrantel base (as Pyrantel Pamoate)...50 mg Made in the U.S.A. Item No. Pyrantel Pamoate oz oz Moe 22 Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

25 Product Index Aspirin USP...10 BotVax B... 4 CHONDROPROTEC Cyanocobalamin 3000 mcg and 5000 mcg EqStim... 5 HYCOAT ImmunoRegulin... 5 Mannitol Injection 20%...19 Natural E Natural E-AD Neogen Vet Salmonella Assay Organic Iodide Powder PanaKare Plus Powder and Tablets... 7 Phos-Aid Pyrantel Pamoate Suspension RenaKare Powder, Tablets and Gel... 8 Sodium Ascorbate Sodium Bicarbonate 8.4% Thiamine Hydrochloride ThyroKare Powder ThyroKare Tablets... 9 Tri-Hist Granules UNIPRIM...12 Vita Vitamin B Complex Vitamin K To order, call 800/ (USA/Canada) inform@neogen.com 23

26 Ordering Information, Terms and Conditions General Sales Policies Neogen s sales policies adhere to the guidelines set forth by the Food, Drug, and Cosmetic Act, which restricts the sale or order of prescription (Rx) veterinary products to a licensed veterinarian. Neogen reserves the right to limit quantity at any time. All prices are subject to change without notice. Product pricing on orders will be determined at current list price at the time of order placement. Ordering Procedures Orders can be placed by: 1. Contacting your Neogen sales professional at 800/ USA/ Canada or 859/ Faxing your orders 24 hours a day, 7 days a week to Neogen at 877/ USA/Canada or 859/ Contacting one of our certified veterinary distributors. Terms 1. All prices are subject to change without prior notice. 2. All product prices are quotes in U.S. funds. 3. An invoice will be issued for each shipment. 4. The gross amount of all purchases is due in full 30 days from the date of invoice. 5. A finance charge may be added to all balances not paid within 60 days of invoice date. For additional information, contact your Neogen sales professional. Payments Please make check payable to: Neogen Corporation Payment with remittance stub should be mailed to: Neogen Corporation Network Place Chicago, IL Wire transfers to: JP Morgan Chase Bank, N.A. ABA# Neogen Corporation Acct. # Swift Code - CHASUS33 For your convenience, we accept Visa, MasterCard, and American Express. Please provide card number upon placement of the order. Freight Terms See current price list for freight terms. Return Goods Policy 1. All returns must be approved in advance by Neogen Corporation. Contact your sales professional at 800/ USA/Canada or 859/ for a Return Goods Authorization. Returns made to Neogen Corporation without approval become the property of Neogen. We reserve the right to declare no credit value. 2. All approved returns must contain a letter stating the product(s) being returned, the lot number(s), and quantity of those products, and a statement that the items have not been subjected to improper storage conditions including extremes in temperature, humidity, smoke, fumes, pressures, age, or radiation due to natural disasters, fires, accidents, or equipment failures. 3. Outdated products may NOT be returned. 4. Special order products or discounted items are non-refundable and non-returnable. 5. No-Charge goods, which may be denoted as Free Goods, Samples, Premium Goods, or Replacement Goods, are non-returnable for replacement, credit or refund. 6. Return freight charges are the responsibility of the customer unless the product was received in error from us, or the product was damaged through shipment. 7. All returns must be received by Neogen as unopened and unmarked selling units (the smallest unit of an item that can be purchased from Neogen). 8. Returns will be accepted from the original purchaser only. 9. The replacement or credit value of a returned product will be issued at the net value when the purchase included a promotional or program special. 10. BotVax B, EqStim, and ImmunoRegulin may not be returned for any reason. 11. Any approved returns are subject to a 20% restocking fee and the customer must sign a letter verifying the proper storage of the returned products. Products Received in Error Errors made by Neogen in accepting, preparing, or shipping any product must be reported by contacting your sales professional within 48 hours from the date of receipt. Products received as a result of these errors may be returned for full credit. Neogen will issue a pick-up and pay all necessary freight. Damage or Shortage During Shipping When damage or shortage is observed at the time of delivery, the carrier s delivery receipt must indicate the specific damage or shortage at the time of receipt. Claims for damage or shortage must be reported by contacting your sales professional at 800/ USA/Canada or 859/ within 48 hours of delivery date. If damage or shortage is observed after signing of the receipt, the customer must notify the carrier and report concealed damage or shortage to Neogen within 48 hours. Neogen will issue a pick-up for these items and will pay the necessary freight. Adverse Reaction or Product Performance Complaints Any adverse reactions or product performance complaints must be reported to Neogen by contacting Technical Services at 800/ USA/Canada or 859/ Neogen Corporation 944 Nandino Blvd. Lexington, KY 40511

27 2014, Neogen Corporation. Neogen, Ag-Tek, BotVax, EqStim, GeneSeek, Ideal, Igenity, ImmunoRegulin, Tri-Hist and UNIPRIM are registered trademarks and PanaKare, RenaKare, ThyroKare, and Vita-15 are trademarks of Neogen Corporation, Lansing MI. HYCOAT and CHONDROPROTEC are registered trademarks of The HyMed Group Corporation. All other trademarks are properties of their respective owners. L

28 944 Nandino Blvd. Lexington, KY / or 800/