European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes *
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1 European Treaty Series - No. 123 European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes * Strasbourg, 18.III.1986 Appendix B Statistical tables and Explanatory notes for their completion (in fulfilment of the requirements in Articles 27 and 28 of the Convention) Introduction General Under Article 27 and 28 of the Convention, each Party shall collect statistical information relating to certain aspects of procedures coming under the Conven tion and communicate this information to the Secretary General of the Council of Europe who shall publish the information received. The method used to collect the information is for each Party to decide and, of course, any additional statistical information may be collected to satisfy national requirements. However, in order to facilitate the work of the Secretary General, the information supplied to him must be comparable and in accordance with the attached tables. Data shall be collected per calendar year. The animals to be counted are those which will be put to a use which may cause them pain, suffering, distress or lasting harm (see Article 1.2.c of the Convention). The counting shall take place when the animals are put to use in a procedure. Each animal shall be counted once only in the same table. Animals not subject to procedures as defined in Article 1.2.c shall not be counted for the purpose of collecting statistical information in the context of this Convention. The very nature of biological research makes it inevitable that occasions will arise when it is difficult to decide in which column of a table an animal being used in a procedure should be recorded. There is no right or wrong method of solving the problem, which is one of individual choice. Subject to such directives as the competent authorities may give, it is for the scientist to decide where to record his animal. It is, however, essential to ensure that no animal is counted twice in the same table. Table 1 The number and kinds of animals used in procedures In this table the total number of animals used in procedures shall be given, this total being broken down by types or classes of animal.
2 Table 2 The number of animals used in procedures for selected purposes This table is intended to show the number of animals used in the broad areas of: fundamental research, development of new products, safety evaluation, diagnosis of disease, and education and training. In column 1, medical includes veterinary medicine. Table 3 The number of animals used in procedures for selected purposes for the protection of man, animals and the environment by toxicological or other safety evaluations This table is intended to give a more detailed breakdown of procedures carried out for the general protection of man, animals and the environment excluding medical purposes. Column 6 includes harmful radiation. Table 4 The number of animals used in procedures concerned with diseases and disorders This table is intended to illustrate the number of animals used for medical purposes, including veterinary medicine, with special reference to three areas of human disease which are of particular public concern. Table 5 The number of animals used in procedures required by law An entry in the column Party only shall be made when the procedure is required by the law of the Party in which the procedure takes place, including international obligations into which that Party has entered (for example as a Party to the Convention on the Elaboration of a European Pharmacopoeia or as a member State of the European Communities). An entry in the column Other Parties only shall be made where the aim of the procedure is specifically to meet requirements, including trade requirements, in countries other than the Party, including also requirements of conventions to which the latter is not a party. Both shall be used where the procedure is intended to meet requirements of both groups; in this case no entry shall be made in either of the other two columns. 2
3 TABLE 1 The number and kinds of animals used in procedures Mice (Mus musculus) Rats (Rattus norvegicus) Guinea pigs (Cavia porcellus) Other rodents (other Rodentia) Rabbits (Oryctolagus cuniculus) Apes (Hominoidea) Other simians (Cercopithecoidea & Ceboidea) Prosimians (Prosimia) Dogs (Canis familiaris) (Felis catus) Other carnivores (other Carnivora) Horses, donkeys and cross-breds (Equidae) Pigs (Sus) Goats and sheep (Capra & Ovis) Cattle (Bos) Other mammals (other Mammalia) Birds (Aves) Reptiles (Reptilia) Amphibians (Amphibia) Fish (Pisces) Total 3
4 TABLE 2 The number of animals used in procedures for selected purposes All species and rabbits 1 Biological (including medical) studies of a fundamental nature 2 Discovery, development and quality control (including safety evaluation) of products or appliances for human and veterinary medicine 3 Diagnosis of disease 4 Protection of man, animals and the environment by toxicological or other safety evaluations 5 Education and training 4
5 TABLE 3 The number of animals used in procedure for selected purposes for the protection of man, animals and the environment by toxicological or other safety evaluations Further classification of Item 4 of Table 2 All species and rabbits 1 Substances used or intended to be used mainly in agriculture 2 Substances used or intended to be used mainly in industry 3 Substances used or intended to be used mainly in households 4 Substances used or intended to be used mainly as cosmetics or toiletries 5 Substances used or intended to be used mainly as additives in food for human consumption 6 Potential or actual hazards of contaminants in the general environment 5
6 TABLE 4 The number of animals used in procedures concerned with diseases and disorders All species and rabbits 1 Cancer (excluding evaluations of carcinogenic hazards) 2 Cardiovascular diseases 3 Nervous and mental disorders 4 Other human and animal diseases Note: When a procedure covers cancer under any item from 2 to 4, the cancer classification should take precedence. 6
7 TABLE 5 The number of animals used in procedures required by law All species and rabbits Party only Other Parties only Both 7
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