Guard against intestinal worms with Palatable All-wormer

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1 Guard against intestinal worms with Palatable All-wormer WHIPWORMS HOOKWORMS TAPEWORMS ROUNDWORMS Palatable All-wormer, for superior, flexible protection of dogs and cats. GENTLE ON PETS, TOUGH ON WORMS. Shaping the future of animal health

2 The endoparasite market presents an exciting opportunity to your clinic. Many of your clients will not understand the importance of a regular worming regime for their pets, nor of the possible disease these parasites can cause in their pet and family if left untreated. Palatable All-Wormer is a unique, flexible product to help you combat endoparasites and inform your clients of the importance of regular worming. Protect your client s pets and family with All-Wormer Palatable PUP ADULT ROUNDWORM PARATENIC HOST E.G. RODENT MATURES TRANS-PLACENTAL TRANS-MAMMARY EGG BITCH LARVAE IN TISSUE LARVAE INFECTIVE 2nd STAGE MAN VISCERAL LARVA MIGRANS Zoonotic potential Roundworms > Ingestion of eggs from unwashed hands after patting animals or ingestion of contaminated soil > Hatched larvae may migrate through the tissues > Visceral larval migrans fever, eosinophilia, enlarged liver > Ocular larval migrans migration to the retina Hookworms > Transcutaneous penetration of larvae cutaneous larval migrans Hydatids* > Hydatid Cysts commonly affect the lungs and liver *New Zealand is currently Provisionally Free from hydatids after many years under an official control programme.

3 Why? Efficacy > Combination of Oxibendazole and Praziquantel to ensure protection against all gastrointestinal parasites of importance in dogs and cats in New Zealand Peace of mind > Gentle mode of action of active ingredients > Can be used in puppies and kittens from two weeks of age > Wide safety margin of active ingredients > Blistered to ensure quality Flexibility > Same tablet for dogs and cats > Dispensing bags to ensure easy prescription > Available in four weight ranges including a 20kg tablet to enable accurate dosing > Tablets quarter scored* > Blistering allows for easy mailing in rural dog runs Compliance > Liver flavoured for palatability > Quarter scored for flexible administration in multi-pet households* *5kg tablet is half scored *5kg tablet is half scored Palatable All-Wormer, for superior protection of dogs and cats!

4 Gentle on pets Mode of action contains Oxibendazole and Praziquantel. Oxibendazole acts by inhibiting or destroying cytoplasmic microtubules in the nematode intestinal or absorptive cells. This in turn inhibits glucose uptake by the parasites and consequently depletion of glycogen stores leading to death of the worms up to several days later. Worms die by being unable to absorb glucose and subsequent depletion of glycogen stores. > As the worms die slowly in situ there is less chance of gastrointestinal upsets in treated animals. > Clients will not be upset by live worms being expelled. > This gentle mode of action enables Palatable All-Wormers to be used on puppies and kittens from two weeks of age, ensuring early treatment of roundworms. Table of efficacy Studies performed in Australia treating dogs with a single dose of Oxibendzole at 22.5mg/kg as a combination wormer with Praziquantel (5mg/kg), confirm the efficacy against roundworms (ascarids), hookworms and whipworms 1 NUMBER OF CASES REDUCTION IN WORM EGGS IN FAECES Ascarid % Hookworm % Whipworm 10 95% 1 Data on file at Virbac A worm count study conducted on 12 dogs in Canberra showed Praziquantel at 5.0mg/kg to be 99% efficacious in the treatment against Echinococcus granulosus infestation in dogs. NUMBER OF S TREATED % EFFICACY Echinococcus granulosus %

5 Tough on worms! Palatable All-Wormer treats and controls all gastrointestinal parasites of importance in New Zealand. ROUNDWORM HOOKWORM TAPEWORM WHIPWORM Dipylidium caninum (Flea Tapeworm), Taenia Toxocara canis, Anclyostoma ovis (Sheep Measles Toxocara cati & caninum & Uncinaria Tapeworm), other Taenia Trichuris vulpis Toxascaris leonina stenocephala species and Echinococcus granulosus* (Hydatid Tapeworm) INFECTION ROUTES Oral, transmammary, transplacental, ingestion of paratenic host Oral, transmammary, transplacental, skin penetration Ingestion of an intermediate host, fleas (Flea Tapeworm), cattle, pigs & sheep Oral Young animals: Cause disease in the CLINICAL SIGNS Poor condition, dull coat, potbellied appearance, vomiting, diarrhoea and occasionally coughing Diarrhoea (tarry coloured or may have frank blood), pale mucus membranes, loss of intermediate host. eg: Sheep Measles in sheep meat, Hydatid Cysts in cattle. The Flea Tapeworm causes anal irritation Diarrhoea, loss of condition, poor coat and possibly abdominal pain condition, death in dogs *New Zealand is currently Provisionally Free from hydatids after many years under an official control programme.

6 Palatable All-wormers for Flexibility Quarter scored* Presented with all necessary dispensing materials *5kg tablet is half scored Available in four convenient weight ranges SMALL AND CAT MEDIUM LARGE EXTRA LARGE Same tablet for dogs and cats! 2.5kg 5kg 10kg 20kg 35kg >35kg 5kg 1/ kg 1/4 1/ /2 20kg 1/4 1/ /4 1/20kg 35kg 1 1/35kg

7 100mg Praziquantel > A higher concentration per tablet enables easy dosing for working dogs. > Available in pottles of 100 tablets. Dispensing bags are available from your wholesaler or Area Sales Manager. > Excellent for rural dog runs for monthly dosing in between treatments. Indicated for the treatment of Tapeworms including Taenia ovis (Sheep Measles Tapeworm).

8 FOR MORE INFORMATION ABOUT, WORMICIDE TAPE AND OTHER VIRBAC PRODUCTS CONTACT YOUR VIRBAC AREA SALES MANAGER Virbac New Zealand Ltd Freephone: Visit us at ACVM Registration No. A7263 Shaping the future of animal health

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